**Please note, these are just some of the many electives offered through the Division of Graduate Medical Sciences and BUSM that previous MSCI students have taken.
GMS CI 660 Good Clinical Practices in Clinical Research
Prereq: consent of instructor. Introduces regulatory responsibilities of sponsors, monitors, and investigators conducting clinical trials. Practical information and exercises are designed on GCP compliance fro m an industrial perspective. Topics include: selecting qualified investigators; obtaining ethical approval for patients, and initiating sites successfully. Group discussions and guest speakers help students learn practical skills. Malikova. 4 cr, Summer II.
GMS CI 680 Ethical Issues in Clinical Research
Prereq: consent of instructor Students examine the development and implementation of regulatory as well as ethical issues involved with conducting clinical trials. Topics covered include: protection of human subjects, privacy and confidentiality, conflicts of interest, negativity toward clinical trials, research on vulnerable subjects, genetic testing and genetic research. Also included are discussions of current ethical issues in clinical research within the media. Baedorf-Kassis, 2 cr, Spring.
GMS CI 671 Applied regression analysis with Computing
Prereq: CI 670. This course covers analytic and computational methods for modeling and regression analysis in the biomedical sciences. Emphasis is on fitting exploratory and inferential models to data in epidemiology and clinical trials. Topics include tabular and graphical summary; the linear, logistic, and Poisson regression models; the Kaplan-Meier method and Cox proportional hazards analysis; power calculation; estimation of effect size. Analyses are presented and completed using the SAS and R software packages. Lecture and laboratory exercises are structured around worked examples from the recent biomedical literature. Evaluation is via homework assignments, a midterm examination, and a final project and presentation. Travison. 3 cr, Spring sem.
GMS CI 793 Professionalism & Thesis Development
Prereq: CI 675 & CI 790 To provide CI students with knowledge of and experience in professional standards, and (2) guidance in developing a thesis proposal and writing a masters level thesis. Topics will include professionalism & professional standards including professional communication, networking and resume and cover letter writing; formal and scientific writing skills, guidance in developing a research topic, and writing a thesis proposal and thesis. The primary aim of this course is to help students adjust from an informal writing style to that required for scientific communication, presentations and theses. Hess Pino, 2 cr, Summer I
GMS CI 691 or 692 Directed Studies in Clinical Investigation
Directed study provides the opportunity for students to explore a special topic of interest under the direction of a MSCI faculty member. Students may register for 2 credits of directed study by submitting a paper registration form, after the MSCI faculty member has agreed to work with the student on a specific project. Directed studies with a non-MSCI faculty member or adjunct member must first be approved by and assigned to the Director or Assistant Director of MSCI as Faculty Sponsor. Directed-Study-Form
GMS CI 801 or 802 Thesis Research in Clinical Investigation
Prereq: 32 credits of course work. The clinical research thesis provides a culminating experience and applies the principles and methods learned in the coursework to a real-life clinical study. To demonstrate the student’s understanding of the clinical research process from both a theoretical and a practical point of view. Hess Pino, 2 cr, variable
GMS MS 621 Bench to Bedside: Translating Biomedical Innovation from Laboratory to the Marketplace
Prereq: consent of instructor. This course covers intellectual property, licensing, and the core aspects of planning, creating, funding, and building new entrepreneurial ventures. Cross disciplinary teams are formed to evaluate current BU translational research projects and their potential as the basis for a start-up company. Gupta 4 cr, Fall.
GMS MM 710 Molecules to Molecular Therapeutics
Prereq: consent of the instructor. This course is designed to provide instruction in all aspects of the translation of basic research observations into clinical applications, using a case study model. The first case study will focus on sickle cell anemia. Lectures will review the molecular genetics of the disease and explore animal models for study of sickle cell anemia and will include laboratory exercises as appropriate.
The course will address treatment strategies for sickle cell disease, including pharmacologic manipulation of globin gene expression, structural biology and rational drug design, and gene therapy. Additional topics related to clinical trials development will be covered including ethical issues, regulatory affairs, statistical considerations in clinical research, and outcome analysis. Required of all molecular medicine graduate students. Seldin, Steinberg. 4 cr, Spring.
GMS AN 715 Professional Skills for Students in the Biomedical Sciences
Prereq: consent of instructor. This course discusses many of the professional skills and ethical issues that are part of an academic biomedical career. Some of the topics include funding mechanisms, determination of authorship, intellectual property, conflict of interest, human and animal subject protection, reviewing responsibilities and mentoring. Zucker. 2 cr, Spring.
GMS PM 730 Introduction to Medical Pharmacology
Prereq: consent of instructor. Principles of pharmacology are covered and several major classes of therapeutic agents, with attention to their mechanisms of action. Issues of current and future concern in medical pharmacology are addressed including problems of drug abuse, the ethics of human experimentation, the pricing of new drugs, and new biotechnological approaches to drug design and development. Walsh, staff. 4 cr, Fall.
GMS PM 800 Advanced General Pharmacology
Prereq: consent of instructor. Lectures and discussions on the major classes of pharmacologic agents, with special attetnion to molecular, cellular, and physiologial mechanisms of therapeutic effects. Boyde, staff. 2 cr, Fall.
GMS PM 881 Drug Discovery and Development
Prereq: consent of instructor. This course will address the discovery and development process for small molecule and protein drug products. Topics will include target identification and validation, lead optimization and selection of drug candidates for clinical testing, and the objectives and design of clinical trials. Williams and Farb. 2 cr, Spring
Fundamentals of Medical Biotechnology
Biotechnology is emerging as one of the fast growing and dominant technologies of the 21st century. It represents a bridging of innovation between physical, biological and medical sciences and depends on entrepreneurship and public acceptance. Medical biotechnology involves the rapid and prudent transformation of basic scientific and medical discoveries into products for the marketplace. This fast-paced transformation creates an urgent need for qualified, capable individuals to promote and manage the rapidly-evolving innovative technologies in a highly complex and competitive ethical, legal, and regulatory environment. Professionals who aspire to become leaders and managers in the emerging field of medical biotechnology must develop a profound understanding of the complexity of medical biotechnology and acquire the needed tools to steer it to a successful outcome. This course introduces students an awareness of the complexities and drivers of medical biotechnology. Franzblau & Traish, 2 cr, Fall
A wide variety of research related courses are available through the Division of Graduate Medical Sciences (GMS Research) and Boston University Medical Campus. The complete course catalog for the Division is available. Please be sure to consult with your adviser before registering for any elective courses.