2016 PhD Publications

Use of an informed search space maximizes confidence of site-specific assignment of glycoprotein glycosylation. Khatri K, Klein JA, Zaia J. Anal Bioanal Chem. 2017 Jan;409(2):607-618. doi: 10.1007/s00216-016-9970-5.

Complete Molecular Weight Profiling of Low-Molecular Weight Heparins Using Size Exclusion Chromatography-Ion Suppressor-High-Resolution Mass Spectrometry. Zaia J, Khatri K, Klein J, Shao C, Sheng Y, Viner R. Anal Chem. 2016 Nov 1;88(21):10654-10660.

Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions. Khatri K, Klein JA, White MR, Grant OC, Leymarie N, Woods RJ, Hartshorn KL, Zaia J. Mol Cell Proteomics. 2016 Jun;15(6):1895-912. doi: 10.1074/mcp.M116.058016.

A review of methods for interpretation of glycopeptide tandem mass spectral data. Hu H, Khatri K, Klein J, Leymarie N, Zaia J. Glycoconj J. 2016 Jun;33(3):285-96. doi: 10.1007/s10719-015-9633-3. Review.

Algorithms and design strategies towards automated glycoproteomics analysis. Hu H, Khatri K, Zaia J. Mass Spectrom Rev. 2016 Jan 4. doi: 10.1002/mas.21487. [Epub ahead of print] Review.

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PE, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, Wolozin B. Cell Rep. 2016 May 17;15(7):1455-66. doi: 10.1016/j.celrep.2016.04.045.

RNF121 Inhibits Angiogenic Growth Factor Signaling by Restricting Cell Surface Expression of VEGFR-2. Maghsoudlou A, Meyer RD, Rezazadeh K, Arafa E, Pudney J, Hartsough E, Rahimi N. Traffic. 2016 Mar;17(3):289-300. doi: 10.1111/tra.12353.

Novel DLK-independent neuronal regeneration in Caenorhabditis elegans shares links with activity-dependent ectopic outgrowth. Chung SH, Awal MR, Shay J, McLoed MM, Mazur E, Gabel CV. Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2852-60. doi: 10.1073/pnas.1600564113.

Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. Goodliffe JW, Olmos-Serrano JL, Aziz NM, Pennings JL, Guedj F, Bianchi DW, Haydar TF. J Neurosci. 2016 Mar 9;36(10):2926-44. doi: 10.1523/JNEUROSCI.2513-15.2016.

Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson’s disease. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Nat Commun. 2016 Jan 12;7:10332. doi: 10.1038/ncomms10332

Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90. Nazari B, Rice LM, Stifano G, Barron AM, Wang YM, Korndorf T, Lee J, Bhawan J, Lafyatis R, Browning JL. Am J Pathol. 2016 Oct;186(10):2650-64. doi: 10.1016/j.ajpath.2016.06.020.

Glutaredoxin-1 deficiency causes fatty liver and dyslipidemia by inhibiting sirtuin-1. Shao D, Han J, Hou X, Fry JL, Behring JB, Seta F, Long M, Roy H, Cohen RA, Matsui R, Bachschmid MM. Antioxid Redox Signal. 2016 Dec 13.

Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson’s Disease. Gorelenkova Miller O, Behring JB, Siedlak SL, Jiang S, Matsui R, Bachschmid MM, Zhu X, Mieyal JJ. Antioxid Redox Signal. 2016 Dec 20;25(18):967-982.

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. JCI Insight. 2016 Nov 17;1(19):e86934.

Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods. Frederiksen R, Nymark S, Kolesnikov AV, Berry JD, Adler L 4th, Koutalos Y, Kefalov VJ, Cornwall MC. J Gen Physiol. 2016 Jul;148(1):1-11. doi: 10.1085/jgp.201511538.

Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods. Berry J, Frederiksen R, Yao Y, Nymark S, Chen J, Cornwall C. J Neurosci. 2016 Jun 29;36(26):6973-87. doi: 10.1523/JNEUROSCI.3544-15.2016.

Representation of memories in the cortical-hippocampal system: Results from the application of population similarity analyses. McKenzie S, Keene CS, Farovik A, Bladon J, Place R, Komorowski R, Eichenbaum H. Neurobiol Learn Mem. 2016 Oct;134 Pt A:178-91. doi: 10.1016/j.nlm.2015.12.008. Review.

Complementary Functional Organization of Neuronal Activity Patterns in the Perirhinal, Lateral Entorhinal, and Medial Entorhinal Cortices. Keene CS, Bladon J, McKenzie S, Liu CD, O’Keefe J, Eichenbaum H. J Neurosci. 2016 Mar 30;36(13):3660-75. doi: 10.1523/JNEUROSCI.4368-15.2016.

Insights into the architecture of the eIF2Bα/β/δ regulatory subcomplex. Bogorad AM, Xia B, Sandor DG, Mamonov AB, Cafarella TR, Jehle S, Vajda S, Kozakov D, Marintchev A. Biochemistry. 2014 Jun 3;53(21):3432-45.

Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Biol Psychiatry. 2016 Oct 25. pii: S0006-3223(16)32940-7. doi: 10.1016/j.biopsych.2016.10.021. [Epub ahead of print]

The interplay between centrosomes and the Hippo tumor suppressor pathway. Bolgioni AF, Ganem NJ. Chromosome Res. 2016 Jan;24(1):93-104. doi: 10.1007/s10577-015-9502-8. Review.

A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes. Chu NK, Shabbir W, Bove-Fenderson E, Araman C, Lemmens-Gruber R, Harris DA, Becker CF. J Biol Chem. 2014 Oct 24;289(43):30144-60. doi: 10.1074/jbc.M114.587345.

The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. Zeldich E, Chen CD, Colvin TA, Bove-Fenderson EA, Liang J, Tucker Zhou TB, Harris DA, Abraham CR. J Biol Chem. 2014 Aug 29;289(35):24700-15. doi: 10.1074/jbc.M114.567321.

Membranous nephropathy: Pilot study of a novel regimen combining cyclosporine and Rituximab. Waldman M, Beck LH Jr, Braun M, Wilkins K, Balow JE, Austin HA 3rd. Kidney Int Rep. 2016 Jul;1(2):73-84.

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms. Brennan MS, Patel H, Allaire N, Thai A, Cullen P, Ryan S, Lukashev M, Bista P, Huang R, Rhodes KJ, Scannevin RH. Antioxid Redox Signal. 2016 Jun 20;24(18):1058-71. doi: 10.1089/ars.2015.6622.

Sensory coding and cognitive processing of sound in Veterans with blast exposure. Bressler S, Goldberg H, Shinn-Cunningham B. Hear Res. 2016 Nov 2. pii: S0378-5955(16)30300-8. doi: 10.1016/j.heares.2016.10.018. [Epub ahead of print]

OS 11-01 Afferent renal nerve modulation of sodium homeostasis and blood pressure: A sodium sensitive PVN Gαi2 protein dependent mechanism countering the development of salt-sensitive hypertension? Wainford R, Carmichael C, Walsh K. J Hypertens. 2016 Sep;34 Suppl 1 – ISH 2016 Abstract Book:e74.

Renal Afferents. Frame AA, Carmichael CY, Wainford RD. Curr Hypertens Rep. 2016 Sep;18(9):69. doi: 10.1007/s11906-016-0676-z. Review.

Inhibition of Ubc13-mediated ubiquitination by GPS2 regulates multiple stages of B cell development. Lentucci C, Belkina A,  Cederquist CT, Chan M, Johnson HE, Prasad S, Lopacinski A, Nikolajczyk BS, Monti S, Snyder Cappione J, Tanasa B, Cardamone MD, Perissi V. J Biol Chem. 2016 Dec 30. pii: jbc.M116.755132.

NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. Chamberland JP, Antonow LT, Dias Santos M, Ritter B. J Cell Sci. 2016 Jul 1;129(13):2625-37. doi: 10.1242/jcs.173708.

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.

Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. JCI Insight. 2016 Nov 17;1(19):e86934.

Objective Measure of Nasal Air Emission Using Nasal Accelerometry. Cler MJ, Lien YS, Braden MN, Mittelman T, Downing K, Stepp CE. J Speech Lang Hear Res. 2016 Oct 1;59(5):1018-1024. doi: 10.1044/2016_JSLHR-S-15-0407.

Surface electromyographic control of a novel phonemic interface for speech synthesis. Cler MJ, Nieto-Castañón A, Guenther FH, Fager SK, Stepp CE. Augment Altern Commun. 2016 Jun;32(2):120-30.

Multiple Running Speed Signals in Medial Entorhinal Cortex. Hinman JR, Brandon MP, Climer JR, Chapman GW, Hasselmo ME. Neuron. 2016 Aug 3;91(3):666-79. doi: 10.1016/j.neuron.2016.06.027.

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells. Coughlan KA, Valentine RJ, Sudit BS, Allen K, Dagon Y, Kahn BB, Ruderman NB, Saha AK. J Biol Chem. 2016 Mar 11;291(11):5664-75. doi: 10.1074/jbc.M115.696849.

SMARCAL1 Resolves Replication Stress at ALT Telomeres. Cox KE, Maréchal A, Flynn RL.Cell Rep. 2016 Feb 9;14(5):1032-40. doi: 10.1016/j.celrep.2016.01.011. Erratum in: Cell Rep. 2016 Mar 22;14(11):2763.

Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. Alsofi L, Daley E, Hornstra I, Morgan EF, Mason ZD, Acevedo JF, Word RA, Gerstenfeld LC, Trackman PC. Calcif Tissue Int. 2016 Feb;98(2):172-85.

Structural stability and local dynamics in disease-causing mutants of human apolipoprotein a-I: what makes the protein amyloidogenic? Das M, Wilson CJ, Mei X, Wales T, Engen JR, Gursky O. Amyloid. 2016 Dec 31:1-2. doi: 10.1080/13506129.2016.1269737. [Epub ahead of print] No abstract available.

Effect of Patient Navigation With or Without Financial Incentives on Viral Suppression Among Hospitalized Patients With HIV Infection and Substance Use: A Randomized Clinical Trial. Metsch LR, Feaster DJ, Gooden L, Matheson T, Stitzer M, Das M, Jain MK, Rodriguez AE, Armstrong WS, Lucas GM, Nijhawan AE, Drainoni ML, Herrera P, Vergara-Rodriguez P, Jacobson JM, Mugavero MJ, Sullivan M, Daar ES, McMahon DK, Ferris DC, Lindblad R, VanVeldhuisen P, Oden N, Castellón PC, Tross S, Haynes LF, Douaihy A, Sorensen JL, Metzger DS, Mandler RN, Colfax GN, del Rio C. JAMA. 2016 Jul 12;316(2):156-70. doi: 10.1001/jama.2016.8914.

Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic? Das M, Wilson CJ, Mei X, Wales TE, Engen JR, Gursky O. J Mol Biol. 2016 Jan 29;428(2 Pt B):449-62. doi: 10.1016/j.jmb.2015.10.029.

Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets. Berdan CA, Erion KA, Burritt NE, Corkey BE, Deeney JT. PLoS One. 2016 Feb 11;11(2):e0149008. doi: 10.1371/journal.pone.0149008

Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks. Frame NM, Gursky O. Amyloid. 2016 Dec 31:1-2. doi: 10.1080/13506129.2016.1270930. [Epub ahead of print] No abstract available.

Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks. Frame NM, Gursky O. FEBS Lett. 2016 Mar;590(6):866-79.

Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Biol Psychiatry. 2016 Oct 25. pii: S0006-3223(16)32940-7.

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination. Olmos-Serrano JL, Kang HJ, Tyler WA, Silbereis JC, Cheng F, Zhu Y, Pletikos M, Jankovic-Rapan L, Cramer NP, Galdzicki Z, Goodliffe J, Peters A, Sethares C, Delalle I, Golden JA, Haydar TF, Sestan N. Neuron. 2016 Mar 16;89(6):1208-22. doi: 10.1016/j.neuron.2016.01.042.

Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. Goodliffe JW, Olmos-Serrano JL, Aziz NM, Pennings JL, Guedj F, Bianchi DW, Haydar TF. J Neurosci. 2016 Mar 9;36(10):2926-44.

MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling. McNew KL, Whipple WJ, Mehta AK, Grant TJ, Ray L, Kenny C, Singh A. Mol Cancer Res. 2016 Dec;14(12):1204-1216.

Molecular Pathogenesis of Pancreatic Cancer. Grant TJ, Hua K, Singh A. Prog Mol Biol Transl Sci. 2016;144:241-275. doi: 10.1016/bs.pmbts.2016.09.008.

Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia. Shaikho EM, Habara AH, Alsultan A, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Patra PK, Sebastiani P, Baltrusaitis K, Farrell JJ, Jiang Z, Luo HY, Chui DH, Al-Ali AK, Steinberg MH. Blood Cells Mol Dis. 2016 Jul;59:49-51.

Minireview: Genetic basis of heterogeneity and severity in sickle cell disease. Habara A, Steinberg MH. Exp Biol Med (Maywood). 2016 Apr;241(7):689-96.

O-fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii. Bandini G, Haserick JR, Motari E, Ouologuem DT, Lourido S, Roos DS, Costello CE, Robbins PW, Samuelson J. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11567-11572.

Saliva and Serum Protein Exchange at the Tooth Enamel Surface. Heller D, Helmerhorst EJ, Oppenheim FG. J Dent Res. 2016 Nov 22. pii: 0022034516680771. [Epub ahead of print]

Microbial Diversity in the Early In Vivo-Formed Dental Biofilm. Heller D, Helmerhorst EJ, Gower AC, Siqueira WL, Paster BJ, Oppenheim FG. Appl Environ Microbiol. 2016 Jan 8;82(6):1881-8. doi: 10.1128/AEM.03984-15.

Physiological Properties of Neurons in Bat Entorhinal Cortex Exhibit an Inverse Gradient along the Dorsal-Ventral Axis Compared to Entorhinal Neurons in Rat. Heys JG, Shay CF, MacLeod KM, Witter MP, Moss CF, Hasselmo ME. J Neurosci. 2016 Apr 20;36(16):4591-9. doi: 10.1523/JNEUROSCI.1791-15.2016.

TAZ activation drives fibroblast spheroid growth, expression of pro-fibrotic paracrine signals, and context dependent ECM gene expression. Jorgenson AJ, Choi KM, Sicard D, Smith KM, Hiemer SE, Varelas X, Tschumperlin DJ. Am J Physiol Cell Physiol. 2016 Nov 23:ajpcell.00205.2016.

Novel microRNA discovery using small RNA sequencing in post-mortem human brain. Wake C, Labadorf A, Dumitriu A, Hoss AG, Bregu J, Albrecht KH, DeStefano AL, Myers RH. BMC Genomics. 2016 Oct 4;17(1):776.

microRNA Profiles in Parkinson’s Disease Prefrontal Cortex. Hoss AG, Labadorf A, Beach TG, Latourelle JC, Myers RH. Front Aging Neurosci. 2016 Mar 1;8:36. doi: 10.3389/fnagi.2016.00036.

The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy. Hsieh IN, Hartshorn KL. Pharmaceuticals (Basel). 2016 Sep 6;9(3). pii: E53.

Disorder Amidst Membrane Order: Standardizing Laurdan Generalized Polarization and Membrane Fluidity Terms. Jay AG, Hamilton JA. J Fluoresc. 2016 Oct 13. [Epub ahead of print] Review.

The enigmatic membrane fatty acid transporter CD36: New insights into fatty acid binding and their effects on uptake of oxidized LDL. Jay AG, Hamilton JA. Prostaglandins Leukot Essent Fatty Acids. 2016 May 20. pii: S0952 3278(16)30029-1.

Extracellular Redox Regulation of Intracellular Reactive Oxygen Generation, Mitochondrial Function and Lipid Turnover in Cultured Human Adipocytes. Jones IV AR, Meshulam T, Oliveira MF, Burritt N, Corkey BE. PLoS One. 2016 Oct 14;11(10):e0164011. doi: 10.1371/journal.pone.0164011.

Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated. Kijewski SD, Akiyama H, Feizpour A, Miller CM, Ramirez NG, Reinhard BM, Gummuluru S. Virology. 2016 Oct;497:328-36.

Central Ghrelin Resistance Permits the Overconsolidation of Fear Memory. Harmatz ES, Stone L, Lim SH, Lee G, McGrath A, Gisabella B, Peng X, Kosoy E, Yao J, Liu E, Machado NJ, Weiner VS, Slocum W, Cunha RA, Goosens KA. Biol Psychiatry. 2016 Nov 29. pii: S0006-3223(16)33053-0.

Nuclear envelope rupture drives genome instability in cancer. Lim S, Quinton RJ, Ganem NJ. Mol Biol Cell. 2016 Nov 1;27(21):3210-3213.

Cognitive and neural consequences of memory suppression in major depressive disorder. Sacchet MD, Levy BJ, Hamilton JP, Maksimovskiy A, Hertel PT, Joormann J, Anderson MC, Wagner AD, Gotlib IH. Cogn Affect Behav Neurosci. 2016 Sep 20. [Epub ahead of print]

Auditory Spatial Coding Flexibly Recruits Anterior, but Not Posterior, Visuotopic Parietal Cortex. Michalka SW, Rosen ML, Kong L, Shinn-Cunningham BG, Somers DC. Cereb Cortex. 2016 Mar;26(3):1302-8.

Cognitive Control Network Contributions to Memory-Guided Visual Attention. Rosen ML, Stern CE, Michalka SW, Devaney KJ, Somers DC. Cereb Cortex. 2016 May;26(5):2059-73.

Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated. Kijewski SD, Akiyama H, Feizpour A, Miller CM, Ramirez NG, Reinhard BM, Gummuluru S. Virology. 2016 Oct;497:328-36.

Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis. Orkaby AR, Ozonoff A, Reisman JI, Miller DR, Zhao S, Rose AJ. J Am Geriatr Soc. 2016 Dec 30.

Who Gets Testosterone? Patient Characteristics Associated with Testosterone Prescribing in the Veteran Affairs System: a Cross-Sectional Study. Jasuja GK, Bhasin S, Reisman JI, Hanlon JT, Miller DR, Morreale AP, Pogach LM, Cunningham FE, Park A, Berlowitz DR, Rose AJ. J Gen Intern Med. 2016 Dec 19

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Rasouly HM, Kumar S, Chan S, Pisarek-Horowitz A, Sharma R, Xi QJ, Nishizaki Y, Higashi Y, Salant DJ, Maas RL, Lu W. Kidney Int. 2016 Dec;90(6):1262-1273.

SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W. JCI Insight. 2016 Nov 17;1(19):e86934.

Acquisition of morphine conditioned place preference increases the dendritic complexity of nucleus accumbens core neurons. Kobrin KL, Moody O, Arena DT, Moore CF, Heinrichs SC, Kaplan GB. Addict Biol. 2016 Nov;21(6):1086-1096. doi: 10.1111/adb.12273.

The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats. Ferragud A, Howell AD, Moore CF, Ta TL, Hoener MC, Sabino V, Cottone P. Neuropsychopharmacology. 2016 Nov 2.

Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis. Li C, Li N, Liu X, Zhang EY, Sun Y, Masuda K, Li J, Sun J, Morrison T, Li X, Chen Y, Wang J, Karim NA, Zhang Y, Blenis J, Reginato MJ, Henske EP, Yu JJ. JCI Insight. 2016 Nov 17;1(19):e86629.

Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium. Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O’Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. Toxicol Sci. 2017 Jan;155(1):248-257. doi: 10.1093/toxsci/kfw198.

The influence of strategic encoding on false memory in patients with mild cognitive impairment and Alzheimer’s disease dementia. Tat MJ, Soonsawat A, Nagle CB, Deason RG, O’Connor MK, Budson AE. Brain Cogn. 2016 Nov;109:50-58. .

Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. Nelson EV, Schmidt KM, Deflubé LR, Doğanay S, Banadyga L, Olejnik J, Hume AJ, Ryabchikova E, Ebihara H, Kedersha N, Ha T, Mühlberger E. J Virol. 2016 Jul 27;90(16):7268-84. doi: 10.1128/JVI.00459-16.

Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination. Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, McKee AC. J Neuropsychiatry Clin Neurosci. 2016 Aug 19:appineuropsych16030043. [Epub ahead of print]

Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players. Montenigro PH, Alosco ML, Martin BM, Daneshvar DH, Mez J, Chaisson CE, Nowinski CJ, Au R, McKee AC, Cantu RC, McClean MD, Stern RA, Tripodis Y. J Neurotrauma. 2017 Jan 15;34(2):328-340. doi: 10.1089/neu.2016.4413.

Characterization of the Neisseria gonorrhoeae Iron and Fur Regulatory Network. Yu C, McClure R, Nudel K, Daou N, Genco CA. J Bacteriol. 2016 Jul 28;198(16):2180-91. doi: 10.1128/JB.00166-16.

Immunologic environment influences macrophage response to Porphyromonas gingivalis. Papadopoulos G, Shaik-Dasthagirisaheb YB, Huang N, Viglianti GA, Henderson AJ, Kantarci A, Gibson FC 3rd. Mol Oral Microbiol. 2016 Jun 27. doi: 10.1111/omi.12168.

A Nationwide Medical Student Assessment of Oncology Education. Mattes MD, Patel KR, Burt LM, Hirsch AE. J Cancer Educ. 2016 Dec;31(4):679-686.

Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life. Patel KR, Aven L, Shao F, Krishnamoorthy N, Duvall MG, Levy BD, Ai X. Mucosal Immunol. 2016 Nov;9(6):1466-1476.

Cryopreserved Human Precision-Cut Lung Slices as a Bioassay for Live Tissue Banking. A Viability Study of Bronchodilation with Bitter-Taste Receptor Agonists. Bai Y, Krishnamoorthy N, Patel KR, Rosas I, Sanderson MJ, Ai X. Am J Respir Cell Mol Biol. 2016 May;54(5):656-63.

Unstable neurons underlie a stable learned behavior. Liberti WA 3rd, Markowitz JE, Perkins LN, Liberti DC, Leman DP, Guitchounts G, Velho T, Kotton DN, Lois C, Gardner TJ. Nat Neurosci. 2016 Dec;19(12):1665-1671.

Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women. Pickering RT, Lee MJ, Karastergiou K, Gower A, Fried SK. PLoS One. 2016 Dec 22;11(12):e0167337.

Neurogenic Niche Microglia Undergo Positional Remodeling and Progressive Activation Contributing to Age-Associated Reductions in Neurogenesis. Solano Fonseca R, Mahesula S, Apple DM, Raghunathan R, Dugan A, Cardona A, O’Connor J, Kokovay E. Stem Cells Dev. 2016 Apr 1;25(7):542-55. doi: 10.1089/scd.2015.0319.

Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells. Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S. Mol Cancer Res. 2016 Jan;14(1):103-13.

MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling. McNew KL, Whipple WJ, Mehta AK, Grant TJ, Ray L, Kenny C, Singh A. Mol Cancer Res. 2016 Dec;14(12):1204-1216.

A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin. Rice LM, Mantero JC, Stifano G, Ziemek J, Simms RW, Gordon J, Domsic R, Lafyatis R. J Invest Dermatol. 2017 Jan;137(1):62-

Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90. Nazari B, Rice LM, Stifano G, Barron AM, Wang YM, Korndorf T, Lee J, Bhawan J, Lafyatis R, Browning JL. A J Pathol. 2016 Oct;186(10):2650-64.

Local skin gene expression reflects both local and systemic skin disease in patients with systemic sclerosis.Rice LM, Stifano G, Ziemek J, Lafyatis R. Rheumatology (Oxford). 2016 Feb;55(2):377-9.

A Mixed-Methods Study of Patient Views on Reflux Symptoms and Medication Routines. Pisegna JM, Yang S, Purcell A, Rubio A. J Voice. 2016 Sep 16. pii: S0892-1997(16)30195-3. doi: 10.1016/j.jvoice.2016.06.024.

Electroencephalogram Coherence Patterns in Autism: An Updated Review. Schwartz S, Kessler R, Gaughan T, Buckley AW. Pediatr Neurol. 2016 Oct 28. pii: S0887-8994(16)30110-2.

Neural correlate of the construction of sentence meaning. Fedorenko E, Scott TL, Brunner P, Coon WG, Pritchett B, Schalk G, Kanwisher N. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6256-E6262.

A new fun and robust version of an fMRI localizer for the frontotemporal language system. Scott TL, Gallée J, Fedorenko E. Cogn Neurosci. 2016 Jul 7:1-10. [Epub ahead of print]

Pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nucleus of the amygdala induces anxiety via melanocortin receptors. Iemolo A, Seiglie M, Blasio A, Cottone P, Sabino V. Psychopharmacology (Berl). 2016 Sep;233(17):3269-77.

Complete Molecular Weight Profiling of Low-Molecular Weight Heparins Using Size Exclusion Chromatography-Ion Suppressor-High-Resolution Mass Spectrometry. Zaia J, Khatri K, Klein J, Shao C, Sheng Y, Viner R. Anal Chem. 2016 Nov 1;88(21):10654-10660.

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans. Dierker T, Shao C, Haitina T, Zaia J, Hinas A, Kjellén L. Sci Rep. 2016 Oct 5;6:34662. doi: 10.1038/srep34662.

The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. Stanford EA, Wang Z, Novikov O, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Seldin DC, Murphy GJ, Sherr DH. BMC Biol. 2016 Mar 16;14:20. doi: 10.1186/s12915-016-0240-y.

Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development. Smith BW, Stanford EA, Sherr DH, Murphy GJ. Stem Cells Int. 2016;2016:2574152.

Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida. Tararina MA, Janda KD, Allen KN. Biochemistry. 2016 Dec 6;55(48):6595-6598.

Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson’s disease. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Nat Commun. 2016 Jan 12;7:10332. doi: 10.1038/ncomms10332.

Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity. Trudeau KM, Colby AH, Zeng J, Las G, Feng JH, Grinstaff MW, Shirihai OS. J Cell Biol. 2016 Jul 4;214(1):25-34.

Murine Mesenchymal Stem Cell Commitment to Differentiation Is Regulated by Mitochondrial Dynamics. Forni MF, Peloggia J, Trudeau K, Shirihai O, Kowaltowski AJ. Stem Cells. 2016 Mar;34(3):743-55. doi: 10.1002/stem.2248.

OS 29-04 Sympathetic Nervous System Regulation Of The Renal Ncc And Blood Pressure During High Dietary Salt Intake. Wainford R, Walsh K. J Hypertens. 2016 Sep;34 Suppl 1 – ISH 2016 Abstract Book:e253-e254.

WNT5A-JNK regulation of vascular insulin resistance in human obesity. Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. Vasc Med. 2016 Dec;21(6):489-496.

OS 11-01 Afferent renal nerve modulation of sodium homeostasis and blood pressure: A sodium sensitive PVN Gαi2 protein dependent mechanism countering the development of salt-sensitive hypertension? Wainford R, Carmichael C, Walsh K. J Hypertens. 2016 Sep;34 Suppl 1 – ISH 2016 Abstract Book:e74.

miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. PLoS One. 2016 Mar 21;11(3):e0151515. doi: 10.1371/journal.pone.0151515.

Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):561-9.

Norepinephrine-evoked salt-sensitive hypertension requires impaired renal sodium chloride cotransporter activity in Sprague-Dawley rats. Walsh KR, Kuwabara JT, Shim JW, Wainford RD. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15;310(2):R115-24. doi: 10.1152/ajpregu.00514.2014.

Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia. Kamata H, Yamamoto K, Wasserman GA, Zabinski MC, Yuen CK, Lung WY, Gower AC, Belkina AC, Ramirez MI, Deng JC, Quinton LJ, Jones MR, Mizgerd JP. Am J Respir Cell Mol Biol. 2016 Sep;55(3):407-18.

Perception of Communicative and Non-communicative Motion-Defined Gestures in Parkinson’s Disease. Jaywant A, Wasserman V, Kemppainen M, Neargarder S, Cronin-Golomb A. J Int Neuropsychol Soc. 2016 May;22(5):540-50.

Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Performed in Acute Perinatal Stroke Reveals Hyperperfusion Associated With Ischemic Injury. Watson CG, Dehaes M, Gagoski BA, Grant PE, Rivkin MJ. Stroke. 2016 Jun;47(6):1514-9. .

Altered Gray Matter in Adolescents with d-Transposition of the Great Arteries. Watson CG, Asaro LA, Wypij D, Robertson RL Jr, Newburger JW, Rivkin MJ. J Pediatr. 2016 Feb;169:36-43.e1.

SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis. Ozturk S, Papageorgis P, Wong CK, Lambert AW, Abdolmaleky HM, Thiagalingam A, Cohen HT, Thiagalingam S. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):638-43.

Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells. Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S. Mol Cancer Res. 2016 Jan;14(1):103-13. doi: 10.1158/1541-7786.MCR-15-0079.

miR-155 in the progression of lung fibrosis in systemic sclerosis. Christmann RB, Wooten A, Sampaio-Barros P, Borges CL, Carvalho CR, Kairalla RA, Feghali-Bostwick C, Ziemek J, Mei Y, Goummih S, Tan J, Alvarez D, Kass DJ, Rojas M, de Mattos TL, Parra E, Stifano G, Capelozzi VL, Simms RW, Lafyatis R. Arthritis Res Ther. 2016 Jul 5;18(1):155.

Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Biol Psychiatry. 2016 Oct 25. pii: S0006-3223(16)32940-7.

MRI assessment of regional differences in phosphorus-31 metabolism and morphological abnormalities of the foot muscles in diabetes. Lin YC, Wu J, Baltzis D, Veves A, Greenman R.J Magn Reson Imaging.2016 Nov;44(5):1132-1142

Anatomy laboratory as an opportunity to educate about skin lesions. Larson AR, Yang CY. Med Teach. 2016 Jun;38(6):637. doi: 10.3109/0142159X.2016.1170791.

Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Biol Psychiatry. 2016 Oct 25. pii: S0006-3223(16)32940-7.

Striatal transcriptome analysis of a congenic mouse line (chromosome 11: 50-60Mb) exhibiting reduced methamphetamine sensitivity. Yazdani N, Shen Y, Johnson WE, Bryant CD. Genom Data. 2016 Apr 11;8:77-80.

RNA-binding proteins, neural development and the addictions. Bryant CD, Yazdani N. Genes Brain Behav. 2016 Jan;15(1):169-86. doi: 10.1111/gbb.12273. Review.