Our Lupus and Autoimmune multidisciplinary center at Boston Medical Center was established in 2013, in collaboration with Rheumatology, Dermatology and OBGYN departments. We currently follow 450 patients with lupus, of them 160 patients with lupus nephritis. We are seeing our patients on Thursdays morning together with our rheumatology and dermatology partners. Once a month we have a designated clinic for new patients as well as for patients with severe disease activity and multiorgan involvement that require complex multidisciplinary care. The coordination of care is done by our lupus patient navigator, who provides our patients with educational materials, and helps to establish their care and social services at BMC. For the purpose of our translational research in order to better understand lupus pathogenesis, we established lupus registry of patients and sample repository where we have collected, annotated, and stored renal biopsy samples, samples for genetic testing, serum and peripheral blood mononuclear cells from patients both at times of high disease activity and during remission. We participate in lupus and lupus nephritis multicenter clinical trials, as we have strong commitment to identify better therapeutic targets for our patients.