GSI 2012 Research Symposium

November 14th, 2012 in Uncategorized

The 2012 Annual Genome Science Institute Research Symposium held on Monday, October 22 was a resounding sucess with participation from both Boston University campuses and seven technology partners.

Seed Grant Recipients for 2012

November 13th, 2012 in Uncategorized

The 2012 Seed Grant Recipients were:

Matthew Jones, PhD, Pulmonary

Collaborators:  Kenneth H. Albrecht, PhD, Medicine, Genetics and Genomic; Caryn L. Navarro, PhD, Medicine


  • To determine whether ZCCHC11 deficiency affects the content level and uridylation of testicular sncRNAs using deep sequencing, mRNA expression using microarrays, and retrotransposon expression using qRT-PCR.
  • To how and when ZCCHC11 deficiency causes germ cell loss leading to infertility by analyzing morphology and marker gene expression in Zcchc11 mutant gonads.

Cesar A. Sommer, PhD, Gastroenterology

Collaborator:  Gustavo Mostoslavsky, PhD, Gastroenterology


  • To interrogate the transcriptome of GIP-expressing K-cells in order to identify genes that define their molecular profile.
  • To investigate the ability of K-cell “identity genes” to modulate the production of GIP and the development of K-cells in vitro.

Sam Thiagalingam, PhD, Biomedical Genetics

Collaborator: Maria I. Ramirez, PhD, Pulmonary Center


  • To test the effect of SDPR over-expression/knock down in in vitro model systems and screening for SDPR expression in tissue microarrays (TMA)
  • In vivo analysis of candidate metastasis suppressor gene, SDPR.

Next Gen Sequencing Working Group

January 26th, 2011 in Uncategorized

The inaugural meeting of the Next Gen Sequencing working group took place on January 24th.  Over 30 individuals attended to discuss the needs of the university for next gen sequencing from library preparation to result analysis.

For the next meeting Andi Broka will present on the LinGA High Performance Compute Cluster and its analytical capabilities and software resources. Additionally, a survey will be prepared to help categorize the university’s needs to help guide the future direction of the working group.

If you are interested in joining the working group, please email to be added to the email list for future events and opportunities.

Next Gen Sequencing Working Group
Computational Resources at BU

Speaker: Andi Broka

February 15th, 3pm-4pm

EBRC Rm X714
650 Albany St
Boston, MA

The Green High Performance Computing Center (GHPCC): How Will It Impact Research Computing at BUMC ?

November 30th, 2010 in Uncategorized

On November 30, John Goodhue, Glenn Bresnahan, and Tracy Shroeder came to BUMC to discuss the Massachusetts Green High Performance Computer Center. This new initiative from five universities wil help keep Boston at the cutting edge of computational research.

For those who were not able to attend the meeting in person or online, you can download the slides from the presentation below.

Update:  The slides from the meeting have been taken down.  If you would like to discuss the GHPCC initiative, please contact

BUSM/BUSPH Study Links Genes to Puberty Timing and Body Fat in Women

November 23rd, 2010 in Uncategorized

“Scientists, including a Boston University School of Public Health (BUSPH) researcher, have discovered 30 new genes that control the age of sexual maturation in women. Notably, many of these genes also act on body weight regulation or biological pathways related to fat metabolism.

The study, which appears in Nature Genetics, was co-authored by Kathryn Lunetta, a BUSPH professor of biostatistics. The study was a collaborative effort by the international ReproGen consortium, which included 175 scientists from 104 worldwide institutions, including Boston University School of Medicine (BUSM) and BUSPH.” ~From BU School of Public Health: The Insider

For the full article, please visit The Insider’s website.

NRC Finds Flaws in Draft of NEIDL Risks

November 19th, 2010 in Uncategorized

From Art Jahnke, BU Today~

“The National Research Council has raised concerns in a letter posted on its website yesterday about the methodology used in an ongoing study of the risks associated with the National Emerging Infectious Diseases Laboratories (NEIDL) on the Boston University Medical Campus.

The NRC found that the risk assessment, which is being supervised by the National Institutes of Health and conducted by the consultancy Tetra Tech, had yet to respond to a recommendation for tiered quantitative and qualitative analyses and that its researchers erred when they used expert opinions as a substitute for absence of actual data on 13 pathogens in a modeling process. The NRC committee, whose concerns stem from a scheduled review of a preliminary draft of the risk assessment, urged Tetra Tech to make a “midcourse correction” and use actual data rather than the opinions of experts.”

For the full article, please visit BU Today.

2nd Annual GSI Research Symposium a Huge Success

October 18th, 2010 in Uncategorized

The 2nd Annual GSI Research Symposium has come and gone this October.  Hundreds of faculty, staff, and students stopped by the Heibert Lounge to support genetic and genomic research at Boston University.

Dozens of posters lined the walls of the 14th floor of the L-Building on the Medical Campus.  Graduate and undergraduate students as well as postdoctoral fellows and faculty were all presenting posters.

Awards were given out to the best student and postdoctoral fellow presenters in multiple categories.


The GSI Symposium Awards Recipients: (top row) Elizabeth Tanner, Badri Vardarajan, Stephanie Correa, Rebecca Kusko, Constantina Christodoulou, Kristen Ott, Stephanie Schneider, Daniel Dworkis; (front row) Catalina Perdomo, Irene Degano, Stephanie van Veen, Cody MacDonald.

Adrienne Cupples receives prestigious award

August 18th, 2010 in Uncategorized

Click below to read about Adrienne’s selection as the most recent recipient of the Janet L. Norwood award.

Longevity Linked to Genes

July 7th, 2010 in Uncategorized

GSI members along with other faculty at Boston University have collaborated to identify genes that can predict longevity.  “The scientists, lead by Paola Sebastiani at the School of Public Health and Thomas Perls at the School of Medicine, have found 150 genetic markers that predict with 77 percent accuracy whether people will live extremely long lives” writes Boston University’s Rich Barlow and Lisa Chedekel.

For the full story, please visit BU Today here.

GSI Faculty Meeting

June 18th, 2010 in Uncategorized

Held last Tuesday, June 15th, in the Evans Biomedical Research Center,  the GSI Faculty Meeting was quite a success.  For those of you who were unable to attend and share your thoughts on the future evolution of genetics and genomics at BU with us, you can find the slides from the presentation here.   Any comments or suggestions can be directed to