Research Efforts

Boston Trauma Institute (BTI) is committed to advancing the care of trauma patients through research – both basic science as well as public health and disparities research.

Prior projects have examined how social determinants of health—education, neighborhood, employment, social support networks, access to health care—impact victims of violence and have utilized this data to develop and implement initiatives that will enhance care delivery for these patients and their families. In addition, the BTI has committed prior efforts towards educating the next generation of trauma surgeons, the public, and policymakers about the role that social determinants and addiction play in violence and traumatic injury. Through advocacy related to addressing the current level of gun violence and other issues at the local and national levels, the BTI is positioned to effect change and contribute to the care of trauma victims on a larger scale.

The following information highlights some – not all – of the current projects performed by the Boston Trauma Institute:

  • The role of heparin in sepsis induced coagulation disorders – A Murine Model 
    • To utilize a murine model of sepsis to determine if heparin will protect organs from injury and improve overall survival
  • Pelvic Angioembolization: A Prospective multi-institutional study 
    • To determine if embolization of patients without an identified arterial source of bleeding, negative angiogram, would aid in hemorrhage control. When the angiogram is positive, to determine which level of embolization, nonselective or selective, is superior? This is an observational study only, and participation should not influence treatment decisions or care in any capacity.
  • Subtotal cholecystectomy for complicated acute cholecystitis: a multicenter prospective observational study
    • To determine the safety and efficacy of subtotal cholecystectomy for treatment of complicated cholecystitis. Additionally, evaluation of the effect of fenestrating vs reconstituting subtypes will be carried out; further elucidating any significant difference the chosen technique has on patient outcomes.
  • Contemporary Management of Right Upper Quadrant Gunshot Wounds
    • To conduct a multi-center retrospective analysis of prospectively-collected data on the contemporary management of isolated right-upper quadrant (RUQ) gunshot wounds

Share this: