Research Week 2022 – Christopher Valente, MD
Title:
Physical Performance in Black and Hispanic Outpatients with Heart Failure: The SCAN-MP Study
Authors:
Christopher J. Valente, MD,a Cody Chiuzan, PhD,b Rabah Alreshq, MD,c Tori Blot,c Denise Fine,c Stephen Helmke,d Carlos Rodriguez,d Natalia Sabogal,c Sergio Teruya,d Morgan Winburn,c Damian Kurian, MD,e Farbod Raiszadeh MD, PhD,e Mathew S. Maurer, MD,d Frederick L. Ruberg, MDc
aBoston University School of Medicine/ Boston Medical Center, Department of Medicine, Boston, MA; bColumbia University, Mailman School of Public Health, New York, NY; cBoston University School of Medicine/ Boston Medical Center, Section of Cardiovascular Medicine, Department of Medicine, Boston, MA; dColumbia University Irving Medical Center, Section of Cardiovascular Medicine, Department of Medicine, New York, NY; and eDivision of Cardiology, Harlem Hospital Center. New York City Health and Hospital Corporation, New York, NY
Abstract
BACKGROUND: Physical function and poor quality of life are associated with adverse health outcomes, however, there are limited data informing the association of these assessments among Black and Hispanic outpatients with heart failure.
METHODS: The multicenter, prospective, Screening for Cardiac Amyloidosis in Minority Populations (SCAN-MP) study identified Black and Hispanic subjects with heart failure, collected baseline characteristics, and measured SPPB. Subjects were followed by telephone and by review of the electronic health record to ascertain outcomes, including heart failure hospitalization and death.
RESULTS: Of 320 participants, 227 (70.9%) had physical deficits, defined by SPPB ≤ 9. Patients with severe physical deficits reported overall lower quality of life scores compared to those with SPPB > 9 (KCCQ Overall Score 57.0 vs. 72.4, p < 0.0001). Patients with worse SPPB-assessed functional deficits also had a greater risk of the composite outcome of heart failure-related hospitalizations or death (severe 19.2% vs. mild 14.6% vs. none 4.3%, p = 0.0067).
CONCLUSIONS: Reduced physical performance, as determined by the SPPB, is highly prevalent among Black and Hispanic outpatients with heart failure, and is associated with overall KCCQ score, as well as an increased risk for the composite outcome of heart failure-related hospitalization or death. These findings suggest that targeted interventions to improve patients’ physical performance may broadly benefit quality of life, as well as reduce hospitalizations and mortality in this population.