Eosinophilia

Today’s resident report focused on the workup of peripheral eosinophilia and pulmonary infiltrates. The patient is a 41 yo F from Haiti presenting with repeated asthma exacerbations and 38% Eos on differential. Broad categories for the differential diagnosis are:

• Infectious (parasitic, fungal)
• Hematologic (hyper-eosinophil syndrome)
• Autoimmune (Churg-Strauss syndrome, eosinophilic pneumonia)
• Allergic Reaction/Hypersensitivity Reaction

Here are some links:

• Churg-Strauss Review
• Evidence that sarcoidosis can sometimes present with peripheral eosoinophilia

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