Richard M. Sherva, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

My primary interest is in exploring the genetic epidemiology of complex disease using linkage and association methods. I’ve worked on cardiovascular phenotypes including hypertension, metabolic syndrome, and stroke, as well as psychiatric diseases including addiction and ADHD, with a focus on gene x (gene, environment, drug treatment) interactions. My future work will likely involve pharmacogenetics and personalized medicine, with specific focus on Alzheimer’s disease.

Publications

  • Published 4/9/2025

    Han X, Zhang Y, Petrosky JN, Bald S, Sherva RM, Labadorf A, Cherry JD, Chung J, Farrell K, Abdolmohammadi B, Durape S, Martin BM, Palmisano JN, Farrell JJ, Alvarez VE, Huber BR, Dwyer B, Daneshvar DH, Dams-O'Connor K, Jun GR, Lunetta KL, Goldstein LE, Katz DI, Cantu RC, Shenton ME, Cummings JL, Reiman EM, Stern RA, Alosco ML, Tripodis Y, Farrer LA, Stein TD, Crary JF, McKee AC, Mez J. A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes. Cell Rep Med. 2025 Apr 09; 102084. PMID: 40239644.

    Read at: PubMed

  • Published 3/14/2025

    Pierce ME, Logue M, Sherva R, Miller M, Huber BR, Milberg W, Hayes JP. Association of Alzheimer's disease genetic risk with age-dependent changes in plasma amyloid-ß42:40 in Veterans. J Alzheimers Dis. 2025 Apr; 104(4):1006-1012. PMID: 40084666.

    Read at: PubMed

  • Published 2/13/2025

    Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez J, Farrer LA. Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures. medRxiv. 2025 Feb 13. PMID: 39990565.

    Read at: PubMed

  • Published 12/18/2024

    Merritt VC, Zhang R, Sherva R, Ly MT, Marra D, Panizzon MS, Tsuang DW, Hauger RL, Logue MW. Curation and validation of electronic medical record-based dementia diagnoses in the VA Million Veteran Program. J Alzheimers Dis. 2025 Jan; 103(1):180-193. PMID: 39692476.

    Read at: PubMed

  • Published 10/1/2024

    Belloy ME, Le Guen Y, Stewart I, Williams K, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD. Role of the X Chromosome in Alzheimer Disease Genetics. JAMA Neurol. 2024 Oct 01; 81(10):1032-1042. PMID: 39250132.

    Read at: PubMed

View All 86 Publications:   View Full Profile in BUMC

Other Positions

  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Member, Genome Science Institute
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • University of Minnesota, PhD
  • University of Minnesota, MPH
  • Gustavus Adolphus College, BA

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