William E. Boden, MD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.

I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.

Publications

  • Published 5/2/2025

    Gorog DA, de Silva R, Boden WE. The year in cardiovascular medicine 2024: the top 10 papers in ischaemic heart disease. Eur Heart J. 2025 May 02; 46(17):1579-1581. PMID: 39995250.

    Read at: PubMed

  • Published 4/1/2025

    Maron DJ, Newman JD, Anthopolos R, Lu Y, Stevens S, Boden WE, Mavromatis K, Linefsky J, Nair RG, Bockeria O, Gosselin G, Perna GP, Demchenko E, Foo D, Shapiro MD, Champagne MA, Ballantyne C, McCullough P, Lopez-Sendon JL, Rockhold F, Harrell F, Rosenberg Y, Stone GW, Bangalore S, Reynolds HR, Spertus JA, Hochman JS. Guideline-Directed Medical Therapy and Outcomes in the ISCHEMIA Trial. J Am Coll Cardiol. 2025 Apr 01; 85(12):1317-1331. PMID: 40139888.

    Read at: PubMed

  • Published 3/1/2025

    Moinul S, Urina-Jassir M, Rodriguez-Taveras J, Peralta AO, Hoffmeister PS, Kinlay S, Yarmohammadi H, Boden WE, Joseph J, Yuyun MF. Meta-Analysis of Racial and Ethnic Disparities in Rhythm Control Strategies for Atrial Fibrillation in the United States. Am J Cardiol. 2025 Jun 15; 245:1-10. PMID: 40032171.

    Read at: PubMed

  • Published 12/20/2024

    Hashem C, Altin SE, Guyton JR, Boden WE. Nonlinearity of the inverse relationship between high-density lipoprotein (HDL) cholesterol and incident cardiovascular risk: Is it time to revisit the "HDL hypothesis"? J Clin Lipidol. 2025; 19(2):238-246. PMID: 39934033.

    Read at: PubMed

  • Published 12/17/2024

    Reynolds HR, Page CB, Shaw LJ, Berman DS, Chaitman BR, Picard MH, Kwong RY, Min JK, Leipsic J, Mancini GBJ, Budoff MJ, Hague CJ, Senior R, Szwed H, Bhargava B, Celutkiene J, Gadkari M, Bainey KR, Doerr R, Ramos RB, Ong P, Naik SR, Steg PG, Goetschalckx K, Chow BJW, Scherrer-Crosbie M, Phillips L, Mark DB, Spertus JA, Alexander KP, O'Brien SM, Boden WE, Bangalore S, Stone GW, Maron DJ, Hochman JS. Relationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial. Circ Cardiovasc Interv. 2024 Dec; 17(12):e013743. PMID: 39689188.

    Read at: PubMed

View All 412 Publications:   View Full Profile in BUMC

Other Positions

  • Lecturer in Medicine
    Harvard Medical School
  • Physician Research Lead & Scientific Director, MAVERIC Center
    VA Boston Healthcare System

Websites

Education

  • State University of New York at Brockport, MD
  • Le Moyne College, BS

View all profiles