William Edward Boden MD

Professor, Cardiovascular Medicine

Lecturer in Medicine

150 S Huntington Avenue | (857) 364-4201
William Boden

Cardiovascular Medicine


I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.

I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.

Other Positions


Medicine-Internal, MD, State University of New York at Brockport, 1974

Biology, BS, Le Moyne College, 1970


Published on 10/2/2021

Arbab-Zadeh A, Zeger SL, Blumenthal RS, Weintraub WS, Boden WE. Advancing high value health care the rising urgency to pivot back Towards hippocratic medicine. Am J Med. 2021 Oct 02. PMID: 34610297.

Published on 9/15/2021

Newman JD, Anthopolos R, Mancini GBJ, Bangalore S, Reynolds HR, Kunichoff DF, Senior R, Peteiro J, Bhargava B, Garg P, Escobedo J, Doerr R, Mazurek T, Gonzalez-Juanatey J, Gajos G, Briguori C, Cheng H, Vertes A, Mahajan S, Guzman LA, Keltai M, Maggioni AP, Stone GW, Berger JS, Rosenberg YD, Boden WE, Chaitman BR, Fleg JL, Hochman JS, Maron DJ. Outcomes of Participants with Diabetes in the ISCHEMIA Trials. Circulation. 2021 Sep 15. PMID: 34521217.

Published on 9/13/2021

Lopez-Sendon JL, Cyr DD, Mark DB, Bangalore S, Huang Z, White HD, Alexander KP, Li J, Nair RG, Demkow M, Peteiro J, Wander GS, Demchenko EA, Gamma R, Gadkari M, Poh KK, Nageh T, Stone PH, Keltai M, Sidhu M, Newman JD, Boden WE, Reynolds HR, Chaitman BR, Hochman JS, Maron DJ, O'Brien SM. Effects of initial invasive vs. initial conservative treatment strategies on recurrent and total cardiovascular events in the ISCHEMIA trial. Eur Heart J. 2021 Sep 13. PMID: 34514494.

Published on 9/1/2021

White HD, O'Brien SM, Alexander KP, Boden WE, Bangalore S, Li J, Manjunath CN, Lopez-Sendon JL, Peteiro J, Gosselin G, Berger JS, Maggioni AP, Reynolds HR, Hochman JS, Maron DJ. Comparison of Days Alive Out of Hospital With Initial Invasive vs Conservative Management: A Prespecified Analysis of the ISCHEMIA Trial. JAMA Cardiol. 2021 Sep 01; 6(9):1023-1031. PMID: 33938917.

Published on 8/18/2021

Boden WE, Caterina R, Taggart DP. Is there equivalence between PCI and CABG surgery in long-term survival of patients with diabetes? Importance of interpretation biases and biological plausibility. Eur Heart J. 2021 Aug 18. PMID: 34405227.

Published on 7/8/2021

Khan SU, Lone AN, Khan MS, Virani SS, Blumenthal RS, Nasir K, Miller M, Michos ED, Ballantyne CM, Boden WE, Bhatt DL. Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. EClinicalMedicine. 2021 Aug; 38:100997. PMID: 34505026.

Published on 7/6/2021

Boden WE, Gersh BJ. Defining the Proper SYNTAX for Long-Term Benefit of Myocardial Revascularization With Optimal Medical Therapy. J Am Coll Cardiol. 2021 07 06; 78(1):39-41. PMID: 34210412.

Published on 6/10/2021

Brown DL, Boden WE. Impact of revascularisation on outcomes in chronic coronary syndromes: a new meta-analysis with the same old biases? Eur Heart J. 2021 Jun 10. PMID: 34110408.

Published on 5/4/2021

Boden WE. RESPONSE: The Exit Interview-of a Professional Lifetime. J Am Coll Cardiol. 2021 May 04; 77(17):2256-2257. PMID: 33926662.

Published on 4/19/2021

Shah R, Nayyar M, Le FK, Labroo A, Nasr A, Rashid A, Davis DA, Weintraub WS, Boden WE. A meta-analysis of optimal medical therapy with or without percutaneous coronary intervention in patients with stable coronary artery disease. Coron Artery Dis. 2021 Apr 19. PMID: 33878073.

View full list of 348 publications.