William Edward Boden MD
Professor, Cardiovascular Medicine
Lecturer in Medicine
150 S Huntington Avenue | (857) 364-4201william.boden@va.gov
Sections
Cardiovascular Medicine
Biography
I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.
I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.
Other Positions
Education
Medicine-Internal, MD, State University of New York at Brockport
Biology, BS, Le Moyne College
Publications
Huded CP, Spertus JA, Jones PG, O'Brien SM, Mark DB, Bangalore S, Stone GW, Williams DO, White HD, Boden WE, Reynolds HR, Hochman JS, Maron DJ. Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA. Circulation. 2025 Sep 23; 152(12):846-858. PMID: 40910165.
Published on 8/29/2025De Caterina R, Bhatt DL, Boden WE. Optimal medical therapy for initial management of stable angina: a call to action. Eur Heart J. 2025 Aug 29. PMID: 40878861.
Published on 8/26/2025Barili F, Dib N, Redberg RF, Boden WE, Kaul S, Parolari A, Anselmi A. From the Hazards of Death to the Hazards of Indication Creep for TAVR. J Am Coll Cardiol. 2025 Aug 26; 86(8):e75-e76. PMID: 40835371.
Published on 6/27/2025De Caterina R, Budoff M, Boden WE. Editorial: Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins. Front Cardiovasc Med. 2025; 12:1597062. PMID: 40656769.
Published on 6/24/2025Barili F, Pollari F, Marin-Cuartas M, Anselmi A, de la Cuesta M, Brophy JM, Boden WE, De Caterina R, Dayan V, Roda JR, Uva MS, Almeida RMS, Tomasi J, Verhoye JP, Musumeci F, Mandrola J, Kaul S, Papatheodorou S, Parolari A. Time-to-event analysis of the long-term outcome in trials comparing transcatheter and surgical aortic valve implantation: A meta-analysis. Int J Cardiol. 2025 Nov 01; 438:133524. PMID: 40571128.
Published on 5/20/2025White HD, O'Brien SM, Boden WE, Fremes SE, Bangalore S, Reynolds HR, Stone GW, Ali ZA, Parakh N, Lopez-Sendon JL, Wang Y, Chen YQ, Mark DB, Chaitman BR, Spertus JA, Maron DJ, Hochman JS. Use of coronary artery bypass graft surgery and percutaneous coronary intervention and associated outcomes in the ISCHEMIA trial. Am Heart J. 2025 Nov; 289:78-94. PMID: 40404111.
Published on 5/2/2025Gorog DA, de Silva R, Boden WE. The year in cardiovascular medicine 2024: the top 10 papers in ischaemic heart disease. Eur Heart J. 2025 May 02; 46(17):1579-1581. PMID: 39995250.
Published on 4/28/2025Boden WE, Kaski JC, Bairey Merz CN, Marzilli M, Pepine CJ, Crea F, De Caterina R. Myocardial Ischaemic Syndromes: Shifting from a Coronary-centric to a Substrate-based Nomenclature is More Accurate and Inclusive. Eur Cardiol. 2025; 20:e12. PMID: 40343144.
Published on 4/1/2025Maron DJ, Newman JD, Anthopolos R, Lu Y, Stevens S, Boden WE, Mavromatis K, Linefsky J, Nair RG, Bockeria O, Gosselin G, Perna GP, Demchenko E, Foo D, Shapiro MD, Champagne MA, Ballantyne C, McCullough P, Lopez-Sendon JL, Rockhold F, Harrell F, Rosenberg Y, Stone GW, Bangalore S, Reynolds HR, Spertus JA, Hochman JS. Guideline-Directed Medical Therapy and Outcomes in the ISCHEMIA Trial. J Am Coll Cardiol. 2025 Apr 01; 85(12):1317-1331. PMID: 40139888.
Published on 3/1/2025Moinul S, Urina-Jassir M, Rodriguez-Taveras J, Peralta AO, Hoffmeister PS, Kinlay S, Yarmohammadi H, Boden WE, Joseph J, Yuyun MF. Meta-Analysis of Racial and Ethnic Disparities in Rhythm Control Strategies for Atrial Fibrillation in the United States. Am J Cardiol. 2025 Jun 15; 245:1-10. PMID: 40032171.
Media Mentions
Published on 6/25/2025
Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins
Published on 2/19/2024
Published on 5/9/2023
Enough PCI ‘Versus’ CABG—Time to Focus on Understudied Groups
Published on 1/25/2022
Optimal Medical Therapy for Stable Angina: Which Drugs? How Long?
Published on 6/28/2021
'Profound' Benefit Found for Staying on Meds Long After Coronary Revascularization
Published on 5/27/2021
Contentious ISCHEMIA Deep Dive: Extent of Revascularization Key?
Published on 5/19/2021
Meta-analysis Muses Over ISCHEMIA Message Had Trial Lasted Longer
Published on 1/5/2021
Stable CAD With High-Risk Anatomy Warrants PCI or CABG, APPROACH Suggests
Published on 6/26/2020
Economic value of alirocumab good if LDL greater than 100 mg/dL
Published on 1/25/2019
A Conversation With William E. Boden, MD, FACC, FAHA
View full list of 11 media mentions.