William Edward Boden MD
Professor, Cardiovascular Medicine
Lecturer in Medicine
150 S Huntington Avenue | (857) 364-4201william.boden@va.gov
Sections
Cardiovascular Medicine
Biography
I am ABIM board-certified in both Internal Medicine and the subspecialty of Cardiovascular Disease. Since 1979, I have held university appointments at Brown University, Wayne State University, Tufts New England Medical Center, Boston University, the University of Connecticut, State University of New York in Buffalo, and Albany Medical College. For the past 27 consecutive years, I have held leadership roles as either a Chief of cardiology or Chief of Medicine at both federal VA facilities and in the academic private sector, all of which have had strong affiliations with their respective academic health centers. In 2016, I re-joined the VA Boston MAVERIC Center as the Scientific Director, Clinical Trials Network, for the VA New England Healthcare System, and as the Research Lead Physician, for VISN 1.
I have extensive prior experience in clinical trials and comparative effectiveness research, and have served in a leadership capacity in several important national and international clinical trials, including as Study Chair for VA CSP-funded VANQWISH and COURAGE Trials, as Study Co-Chair of the NIH-funded AIM-HIGH Trial, and as a national co-PI for the NIH-funded ISCHEMIA Trial. My principal research interests include studies in stable ischemic heart disease, post-MI secondary prevention, acute coronary syndromes, and preventive cardiology.
Other Positions
Education
Medicine-Internal, MD, State University of New York at Brockport
Biology, BS, Le Moyne College
Publications
Gorog DA, de Silva R, Boden WE. The year in cardiovascular medicine 2025: the top 10 papers in ischaemic heart disease. Eur Heart J. 2026 Feb 23. PMID: 41725250.
Published on 2/19/2026Chiu N, Bhatt DL, De Caterina R, Doenst T, Kirov H, Dayan V, Faxon DP, Kaul S, Perera D, Puskas JD, Steg PG, Boden WE. Invasive and medical management approaches to non-acute myocardial ischaemic syndromes. Nat Rev Cardiol. 2026 Feb 19. PMID: 41714707.
Published on 12/30/2025Lopes MS, Boden WE. Early combination therapy for angina pectoris: How COMBINE offers new management insights to an old drug. Int J Cardiol. 2026 Mar 15; 447:134133. PMID: 41478451.
Published on 9/14/2025Kawczynski MJ, Barili F, Brophy JM, De Caterina R, Biondi Zoccai G, Anselmi A, Boden WE, Parolari A, Heuts S. Revascularisation strategies for non-acute myocardial ischaemic syndromes. Heart. 2025 Sep 14. PMID: 40947142.
Published on 9/5/2025Huded CP, Spertus JA, Jones PG, O'Brien SM, Mark DB, Bangalore S, Stone GW, Williams DO, White HD, Boden WE, Reynolds HR, Hochman JS, Maron DJ. Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA. Circulation. 2025 Sep 23; 152(12):846-858. PMID: 40910165.
Published on 8/29/2025De Caterina R, Bhatt DL, Boden WE. Optimal medical therapy for initial management of stable angina: a call to action. Eur Heart J. 2025 Aug 29. PMID: 40878861.
Published on 8/26/2025Barili F, Dib N, Redberg RF, Boden WE, Kaul S, Parolari A, Anselmi A. From the Hazards of Death to the Hazards of Indication Creep for TAVR. J Am Coll Cardiol. 2025 Aug 26; 86(8):e75-e76. PMID: 40835371.
Published on 6/27/2025De Caterina R, Budoff M, Boden WE. Editorial: Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins. Front Cardiovasc Med. 2025; 12:1597062. PMID: 40656769.
Published on 6/24/2025Barili F, Pollari F, Marin-Cuartas M, Anselmi A, de la Cuesta M, Brophy JM, Boden WE, De Caterina R, Dayan V, Roda JR, Uva MS, Almeida RMS, Tomasi J, Verhoye JP, Musumeci F, Mandrola J, Kaul S, Papatheodorou S, Parolari A. Time-to-event analysis of the long-term outcome in trials comparing transcatheter and surgical aortic valve implantation: A meta-analysis. Int J Cardiol. 2025 Nov 01; 438:133524. PMID: 40571128.
Published on 5/20/2025White HD, O'Brien SM, Boden WE, Fremes SE, Bangalore S, Reynolds HR, Stone GW, Ali ZA, Parakh N, Lopez-Sendon JL, Wang Y, Chen YQ, Mark DB, Chaitman BR, Spertus JA, Maron DJ, Hochman JS. Use of coronary artery bypass graft surgery and percutaneous coronary intervention and associated outcomes in the ISCHEMIA trial. Am Heart J. 2025 Nov; 289:78-94. PMID: 40404111.
Media Mentions
Published on 2/4/2026
Experimental cholesterol-lowering pill may offer new option for millions
Published on 6/25/2025
Therapeutic strategies to lower residual dyslipidemic CV risk beyond LDL-C and statins
Published on 2/19/2024
Published on 5/9/2023
Enough PCI ‘Versus’ CABG—Time to Focus on Understudied Groups
Published on 1/25/2022
Optimal Medical Therapy for Stable Angina: Which Drugs? How Long?
Published on 6/28/2021
'Profound' Benefit Found for Staying on Meds Long After Coronary Revascularization
Published on 5/27/2021
Contentious ISCHEMIA Deep Dive: Extent of Revascularization Key?
Published on 5/19/2021
Meta-analysis Muses Over ISCHEMIA Message Had Trial Lasted Longer
Published on 1/5/2021
Stable CAD With High-Risk Anatomy Warrants PCI or CABG, APPROACH Suggests
Published on 6/26/2020
Economic value of alirocumab good if LDL greater than 100 mg/dL
View full list of 12 media mentions.