Nir Ayalon MD

Clinical Associate Professor, Cardiovascular Medicine

Attending Physician, Cardiovascular Medicine

75 E. Newton St | (617) 638-8767
Nir Ayalon

Cardiovascular Medicine


Dr. Nir Ayalon is an Interventional Cardiologist with special interests in Heart Failure, Pulmonary Hypertension, and Invasive Hemodynamics, as well as in new medical technologies and healthcare innovation. Dr. Ayalon is the Co-Director of the Invasive Physiology and Hemodynamics Lab (IPH-Lab), offering a customizable invasive test to diagnose unexplained dyspnea, allowing an early diagnosis of Exercise-induced Heart Failure and Pulmonary Hypertension. Dr. Ayalon is the Director of the Heart Failure Remote Monitoring program, utilizing Pulmonary pressure sensors (Abbott's CardioMEMS) to prevent Heart Failure hospitalizations. Dr. Ayalon had completed his medical school in Israel, had served as a physician in unique and classified units in the Israeli Defense Forces, and had completed his Internal Medicine Residency at Tel-Aviv Medical Center. Dr. Ayalon was trained at Boston University/Boston Medical Center and completed a general cardiology fellowship, a heart failure and cardiomyopathy clinical and research fellowship and an Interventional cardiology fellowship. Dr. Ayalon is now a Clinical Associate Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine and practices as an attending physician in Interventional Cardiology, Cardiac Intensive Care, and Heart Failure services and the IPH-Lab at Boston University and Boston Medical Center.

Other Positions


MD, Ben-Gurion University of the Negev

Medical Science, BMedSc, Ben-Gurion University of the Negev


Published on 6/20/2023

Ayalon N, Jacobs AK. Enhancing Regional ST-Segment-Elevation Myocardial Infarction Care: A Shock to the System. Circ Cardiovasc Interv. 2023 Jun; 16(6):e013177. PMID: 37339238.

Published on 6/10/2023

Li Y, Gray A, Xue L, Farb MG, Ayalon N, Andersson C, Ko D, Benjamin EJ, Levy D, Vasan RS, Larson MG, Rong J, Xanthakis V, Liu C, Fetterman JL, Gopal DM. Metabolomic Profiles, Ideal Cardiovascular Health, and Risk of Heart Failure and Atrial Fibrillation: Insights From the Framingham Heart Study. J Am Heart Assoc. 2023 Jun 20; 12(12):e028022. PMID: 37301766.

Published on 11/2/2022

Moreira JD, Gower AC, Xue L, Alekseyev Y, Smith KK, Choi SH, Ayalon N, Farb MG, Tenan K, LeClerc A, Levy D, Benjamin EJ, Lenburg ME, Mitchell RN, Padera RF, Fetterman JL, Gopal DM. Systematic dissection, preservation, and multiomics in whole human and bovine hearts. Cardiovasc Pathol. 2023; 63:107495. PMID: 36334690.

Published on 4/2/2019

Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 04 02; 8(7):e011100. PMID: 30929550.

Published on 7/24/2017

Ho JE, Rahban Y, Sandhu H, Hiremath PG, Ayalon N, Qin F, Perez AJ, Downing J, Gopal DM, Cheng S, Colucci WS. Preclinical Alterations in Myocardial Microstructure in People with Metabolic Syndrome. Obesity (Silver Spring). 2017 Sep; 25(9):1516-1522. PMID: 28737258.

Published on 2/8/2016

Ayalon N, Jacobs AK. Incomplete Revascularization in Patients Treated With Percutaneous Coronary Intervention: When Enough Is Enough. JACC Cardiovasc Interv. 2016 Feb 8; 9(3):216-8. PMID: 26847113.

Published on 7/14/2015

Wang YC, Liang CS, Gopal DM, Ayalon N, Donohue C, Santhanakrishnan R, Sandhu H, Perez AJ, Downing J, Gokce N, Colucci WS, Ho JE. Preclinical Systolic and Diastolic Dysfunctions in Metabolically Healthy and Unhealthy Obese Individuals. Circ Heart Fail. 2015 Sep; 8(5):897-904. PMID: 26175540.

Published on 3/10/2015

Gopal DM, Santhanakrishnan R, Wang YC, Ayalon N, Donohue C, Rahban Y, Perez AJ, Downing J, Liang CS, Gokce N, Colucci WS, Ho JE. Impaired right ventricular hemodynamics indicate preclinical pulmonary hypertension in patients with metabolic syndrome. J Am Heart Assoc. 2015 Mar; 4(3):e001597. PMID: 25758604.

Published on 7/1/2014

Ayalon N, Gopal DM, Mooney DM, Simonetti JS, Grossman JR, Dwivedi A, Donohue C, Perez AJ, Downing J, Gokce N, Miller EJ, Liang CS, Apovian CM, Colucci WS, Ho JE. Preclinical left ventricular diastolic dysfunction in metabolic syndrome. Am J Cardiol. 2014 Sep 15; 114(6):838-42. PMID: 25084691.

Published on 4/28/2013

Ayalon N, Flore LA, Christensen TG, Sam F. Mitochondrial encoded NADH dehydrogenase 5 (MT-ND5) gene point mutation presents as late onset cardiomyopathy. Int J Cardiol. 2013 Sep 1; 167(5):e143-5. PMID: 23628297.

View full list of 14 publications.