Joseph Anthony Politch PhD
Research Associate Professor, Infectious Diseases
670 Albany St | (617) 414-8482joseph.politch@bmc.org
politch@bu.edu

Sections
Infectious Diseases
Education
Psychology, PhD, Temple University
Experimental Psychology, MS, Bucknell University
Psychology, BS, University of Scranton
Publications
Nador E, Mausser E, Marathe JG, Politch JA, Thurman AR, Whaley KJ, Anderson DJ. Antibody-dependent complement-mediated sperm cytotoxicity in the endocervix is a dominant contraceptive mechanism of ZB-06 vaginal film. Fertil Steril. 2024 Oct 22. PMID: 39447830.
Published on 7/25/2024Johnson JA, Li JF, Politch JA, Lipscomb JT, Tino AS, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen Under Integrase Strand Transfer Inhibitor-Based Therapy Are Largely Myeloid Cell-Derived and Disparate. J Infect Dis. 2024 Jul 25; 230(1):78-85. PMID: 39052738.
Published on 2/13/2024Johnson JA, Li JF, Politch JA, Lipscomb JT, Santos Tino A, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen under INSTI-based Therapy are Largely Myeloid Cell-Derived and Disparate from Circulating Provirus. J Infect Dis. 2024 Feb 13. PMID: 38356153.
Published on 1/9/2024Dohadwala S, Geib MT, Politch JA, Anderson DJ. Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy. Front Reprod Health. 2023; 5:1337479. PMID: 38264184.
Published on 6/13/2023Dohadwala S, Politch JA, Barmine JH, Anderson DJ. A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products. Open Access J Contracept. 2023; 14:83-94. PMID: 37332341.
Published on 3/30/2023Mausser E, Nador E, Politch JA, Pauly MR, Marathe JG, Moench TR, Zeitlin L, Whaley KJ, Anderson DJ. LALAPG variant of the Human Contraception Antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity. PLoS One. 2023; 18(3):e0282147. PMID: 36996137.
Published on 3/2/2023Thurman AR, Moench TR, Hoke M, Politch JA, Cabral H, Mausser E, Nador E, Morton J, Hamorsky K, Swope K, Bratcher B, Anderson DJ, Whaley KJ. ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study. Am J Obstet Gynecol. 2023 Jun; 228(6):716.e1-716.e12. PMID: 36870409.
Published on 11/5/2021Handal-Orefice RC, McHale M, Friedman AM, Politch JA, Kuohung W. Impact of race versus ethnicity on infertility diagnosis between Black American, Haitian, African, and White American women seeking infertility care: a retrospective review. F S Rep. 2022 May; 3(2 Suppl):22-28. PMID: 35937451.
Published on 7/10/2021Baldeon-Vaca G, Marathe JG, Politch JA, Mausser E, Pudney J, Doud J, Nador E, Zeitlin L, Pauly M, Moench TR, Brennan M, Whaley KJ, Anderson DJ. Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women. EBioMedicine. 2021 Jul; 69:103478. PMID: 34256345.
Published on 2/3/2021Politch JA, Cu-Uvin S, Moench TR, Tashima KT, Marathe JG, Guthrie KM, Cabral H, Nyhuis T, Brennan M, Zeitlin L, Spiegel HML, Mayer KH, Whaley KJ, Anderson DJ. Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial. PLoS Med. 2021 02; 18(2):e1003495. PMID: 33534791.