Frederick Lief Ruberg MD

Professor, Cardiovascular Medicine

Professor, Radiology

75 E. Newton St | (617) 638-8968
Frederick Ruberg
Sections

Cardiovascular Medicine

Centers

Whitaker Cardiovascular Institute

Amyloidosis Center

Biography

Dr. Ruberg's clinical and research expertise is in the field of cardiac imaging including echocardiography and cardiovascular magnetic resonance imaging (CMR). Dr. Ruberg applies imaging in research designed to facilitate improved diagnosis and management of the infiltrative cardiomyopathy cardiac amyloidosis.

Other Positions

Education

Medicine-Internal, MD, University of Pennsylvania School of Medicine

Psychology, BA, Haverford College

Publications

Published on 6/10/2024

Thel MC, Cochran JD, Teruya S, Hayashi O, Xie CR, Srinivasan AR, Chavkin NW, Arai Y, Sano S, Mirabal Santos A, De Los Santos J, Fine D, Sabogal N, Ullah I, Helmke S, Rodriguez C, Prokaeva T, Foster RH, Spencer BH, Izumiya Y, Maurer MS, Walsh K, Ruberg FL. Mosaic Loss of the Y Chromosome Is Enriched in Patients With Wild-Type Transthyretin Cardiac Amyloidosis and Associated With Increased Mortality. Circ Heart Fail. 2024 Jun 10; e011681. PMID: 38853760.

Published on 6/4/2024

Maurer MS, Miller EJ, Ruberg FL. Addressing Health Disparities-The Case for Variant Transthyretin Cardiac Amyloidosis Grows Stronger. JAMA. 2024 Jun 04; 331(21):1809-1811. PMID: 38734953.

Published on 6/4/2024

Maurer MS, Soman P, Hernandez A, Garcia-Pavia P, Signorovitch J, Wei LJ, Hanna M, Ruberg FL, Kittleson M, Kazi D, Dorbala S, Hsu K, Lousada I, Adigun R, Dunnmon P, Kelly J, Gillmore J. Advancing Transthyretin Amyloidosis Drug Development in an Evolving Treatment Landscape: Amyloidosis Forum Meeting Proceedings. Adv Ther. 2024 Jul; 41(7):2723-2742. PMID: 38833142.

Published on 5/30/2024

Katznelson E, Jerosch-Herold M, Cuddy SAM, Clerc OF, Benz DC, Taylor A, Rao S, Kijewski MF, Liao R, Landau H, Yee AJ, Ruberg FL, Di Carli MF, Falk RH, Kwong RY, Dorbala S. Mechanisms of left ventricular systolic dysfunction in light chain amyloidosis: a multiparametric cardiac MRI study. Front Cardiovasc Med. 2024; 11:1371810. PMID: 38873265.

Published on 5/11/2024

Wardhere A, Bampatsias D, Cohn E, Fine D, Freitas C, Gallegos C, Helmke S, Ionescu N, Ivrose J, Rodriguez C, Sabogal N, Fils S, Henry T, Teruya S, Ullah I, Kurian D, Raiszadeh F, Miller EJ, Ruberg FL, Maurer MS. Unlocking Diversity in Cardiovascular Clinical Research: Lessons from the Screening for Cardiac Amyloidosis With Nuclear Imaging in a Minority Populations Study. J Card Fail. 2024 May 11. PMID: 38740174.

Published on 4/30/2024

Datar Y, Clerc OF, Cuddy SAM, Kim S, Taylor A, Neri JC, Benz DC, Bianchi G, Yee AJ, Sanchorawala V, Ruberg FL, Landau H, Liao R, Kijewski MF, Jerosch-Herold M, Kwong RY, Di Carli MF, Falk RH, Dorbala S. Quantification of right ventricular amyloid burden with 18F-florbetapir positron emission tomography/computed tomography and its association with right ventricular dysfunction and outcomes in light-chain amyloidosis. Eur Heart J Cardiovasc Imaging. 2024 Apr 30; 25(5):687-697. PMID: 38193678.

Published on 3/16/2024

Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Bawa PS, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. bioRxiv. 2024 Mar 16. PMID: 38558967.

Published on 3/5/2024

Ruberg FL, Maurer MS. Cardiac Amyloidosis Due to Transthyretin Protein: A Review. JAMA. 2024 Mar 05; 331(9):778-791. PMID: 38441582.

Published on 2/22/2024

Datar Y, Cuddy SAM, Ovsak G, Giblin GT, Maurer MS, Ruberg FL, Arnaout R, Dorbala S. Myocardial Texture Analysis of Echocardiograms in Cardiac Transthyretin Amyloidosis. J Am Soc Echocardiogr. 2024 May; 37(5):570-573. PMID: 38395112.

Published on 2/20/2024

Ruberg FL, Gropler RJ. In This Issue of the Journal. Circ Cardiovasc Imaging. 2024 Feb; 17(2):e016675. PMID: 38377239.

View full list of 137 publications.