Frederick Lief Ruberg MD
Professor, Cardiovascular Medicine
Professor, Radiology
75 E. Newton St | (617) 638-8968f.ruberg@bmc.org
frederick.ruberg@bmc.org
frruberg@bu.edu
![Frederick Ruberg](/medicine/files/2020/06/Frederick-Ruberg-1.jpg)
Sections
Cardiovascular Medicine
Centers
Whitaker Cardiovascular Institute
Amyloidosis Center
Biography
Dr. Ruberg's clinical and research expertise is in the field of cardiac imaging including echocardiography and cardiovascular magnetic resonance imaging (CMR). Dr. Ruberg applies imaging in research designed to facilitate improved diagnosis and management of the infiltrative cardiomyopathy cardiac amyloidosis.
Other Positions
Education
Medicine-Internal, MD, University of Pennsylvania School of Medicine
Psychology, BA, Haverford College
Publications
Thel MC, Cochran JD, Teruya S, Hayashi O, Xie CR, Srinivasan AR, Chavkin NW, Arai Y, Sano S, Mirabal Santos A, De Los Santos J, Fine D, Sabogal N, Ullah I, Helmke S, Rodriguez C, Prokaeva T, Foster RH, Spencer BH, Izumiya Y, Maurer MS, Walsh K, Ruberg FL. Mosaic Loss of the Y Chromosome Is Enriched in Patients With Wild-Type Transthyretin Cardiac Amyloidosis and Associated With Increased Mortality. Circ Heart Fail. 2024 Jun 10; e011681. PMID: 38853760.
Published on 6/4/2024Maurer MS, Miller EJ, Ruberg FL. Addressing Health Disparities-The Case for Variant Transthyretin Cardiac Amyloidosis Grows Stronger. JAMA. 2024 Jun 04; 331(21):1809-1811. PMID: 38734953.
Published on 6/4/2024Maurer MS, Soman P, Hernandez A, Garcia-Pavia P, Signorovitch J, Wei LJ, Hanna M, Ruberg FL, Kittleson M, Kazi D, Dorbala S, Hsu K, Lousada I, Adigun R, Dunnmon P, Kelly J, Gillmore J. Advancing Transthyretin Amyloidosis Drug Development in an Evolving Treatment Landscape: Amyloidosis Forum Meeting Proceedings. Adv Ther. 2024 Jul; 41(7):2723-2742. PMID: 38833142.
Published on 5/30/2024Katznelson E, Jerosch-Herold M, Cuddy SAM, Clerc OF, Benz DC, Taylor A, Rao S, Kijewski MF, Liao R, Landau H, Yee AJ, Ruberg FL, Di Carli MF, Falk RH, Kwong RY, Dorbala S. Mechanisms of left ventricular systolic dysfunction in light chain amyloidosis: a multiparametric cardiac MRI study. Front Cardiovasc Med. 2024; 11:1371810. PMID: 38873265.
Published on 5/11/2024Wardhere A, Bampatsias D, Cohn E, Fine D, Freitas C, Gallegos C, Helmke S, Ionescu N, Ivrose J, Rodriguez C, Sabogal N, Fils S, Henry T, Teruya S, Ullah I, Kurian D, Raiszadeh F, Miller EJ, Ruberg FL, Maurer MS. Unlocking Diversity in Cardiovascular Clinical Research: Lessons from the Screening for Cardiac Amyloidosis With Nuclear Imaging in a Minority Populations Study. J Card Fail. 2024 May 11. PMID: 38740174.
Published on 4/30/2024Datar Y, Clerc OF, Cuddy SAM, Kim S, Taylor A, Neri JC, Benz DC, Bianchi G, Yee AJ, Sanchorawala V, Ruberg FL, Landau H, Liao R, Kijewski MF, Jerosch-Herold M, Kwong RY, Di Carli MF, Falk RH, Dorbala S. Quantification of right ventricular amyloid burden with 18F-florbetapir positron emission tomography/computed tomography and its association with right ventricular dysfunction and outcomes in light-chain amyloidosis. Eur Heart J Cardiovasc Imaging. 2024 Apr 30; 25(5):687-697. PMID: 38193678.
Published on 3/16/2024Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Bawa PS, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. bioRxiv. 2024 Mar 16. PMID: 38558967.
Published on 3/5/2024Ruberg FL, Maurer MS. Cardiac Amyloidosis Due to Transthyretin Protein: A Review. JAMA. 2024 Mar 05; 331(9):778-791. PMID: 38441582.
Published on 2/22/2024Datar Y, Cuddy SAM, Ovsak G, Giblin GT, Maurer MS, Ruberg FL, Arnaout R, Dorbala S. Myocardial Texture Analysis of Echocardiograms in Cardiac Transthyretin Amyloidosis. J Am Soc Echocardiogr. 2024 May; 37(5):570-573. PMID: 38395112.
Published on 2/20/2024Ruberg FL, Gropler RJ. In This Issue of the Journal. Circ Cardiovasc Imaging. 2024 Feb; 17(2):e016675. PMID: 38377239.
Media Mentions
Published on 7/1/2024
New study shows a relationship between heart disease and spontaneous loss of Y chromosome
Published on 7/1/2024
Concerning link discovered between heart disease and disappearance of the Y chromosome
Published on 6/27/2024
Published on 5/8/2024
6 Signs of Heart Problems Even Young People Should Know
Published on 8/17/2023
Staying Active Safely: Exercise Tips If You Have ATTR-CM
Published on 1/7/2022
Heart Failure Imaging: Where Are We Now?
Published on 9/4/2019
Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations
Published on 6/4/2019
Cardiac Transthyretin Amyloidosis Often Diagnosed Late
Published on 10/15/2018
Carpal Tunnel Surgery a Chance to Catch Amyloid Heart Disease
View full list of 9 media mentions.