Arjun Guha PhD

Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine

72 E. Concord Street | (617) 638-4860
Arjun Guha
Sections

Pulmonary, Allergy, Sleep & Critical Care Medicine

Centers

Evans Center for Interdisciplinary Biomedical Research

Biography

Research Interests: Cell fate specification and cellular plasticity in lung development and repair, Non-classical stem cell hierarchies, Pulmonary neuroepithelial cells and their microenvironment, and Notch signaling

Education

Cell & Molecular Biology, PhD, Manipal University, 2002

Biology, BS, Wabash College, 1995

Publications

Published on 10/8/2021

Kizhedathu A, Chhajed P, Yeramala L, Sain Basu D, Mukherjee T, Vinothkumar KR, Guha A. Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts. Elife. 2021 Oct 08; 10. PMID: 34622778.

Published on 9/2/2020

Kizhedathu A, Kunnappallil RS, Bagul AV, Verma P, Guha A. Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts. Elife. 2020 09 02; 9. PMID: 32876044.

Published on 4/16/2018

Kizhedathu A, Bagul AV, Guha A. Negative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and tracheal hypertrophy in Drosophila. Elife. 2018 04 16; 7. PMID: 29658881.

Published on 4/11/2017

Guha A, Deshpande A, Jain A, Sebastiani P, Cardoso WV. Uroplakin 3a+ Cells Are a Distinctive Population of Epithelial Progenitors that Contribute to Airway Maintenance and Post-injury Repair. Cell Rep. 2017 Apr 11; 19(2):246-254. PMID: 28402849.

Published on 10/22/2015

Rao PR, Lin L, Huang H, Guha A, Roy S, Kornberg TB. Developmental compartments in the larval trachea of Drosophila. Elife. 2015 Oct 22; 4. PMID: 26491942.

Published on 7/16/2015

Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S. Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16; 15:72. PMID: 26178733.

Published on 2/21/2014

Guha A, Vasconcelos M, Zhao R, Gower AC, Rajagopal J, Cardoso WV. Analysis of Notch signaling-dependent gene expression in developing airways reveals diversity of Clara cells. PLoS One. 2014; 9(2):e88848. PMID: 24586412.

Published on 7/13/2012

Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV. Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12592-7. PMID: 22797898.

Published on 9/12/2009

Guha A, Lin L, Kornberg TB. Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis. Dev Biol. 2009 Nov 15; 335(2):317-26. PMID: 19751719.

Published on 7/29/2008

Guha A, Lin L, Kornberg TB. Organ renewal and cell divisions by differentiated cells in Drosophila. Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31):10832-6. PMID: 18664581.

View full list of 12 publications.