Andrew J. Henderson PhD
Professor, Infectious Diseases
Assistant Dean, Oral Health Sciences
650 Albany St | (617) 414-5240andrew.henderson@bmc.org
hender@bu.edu

Sections
Infectious Diseases
Centers
BU-BMC Cancer Center
Evans Center for Interdisciplinary Biomedical Research
Biography
Research in my laboratory focuses on cellular mechanisms that regulate HIV replication and transcription. Current projects include exploring how signaling influences HIV infection and latency, devising strategies for long-term repression of HIV provirus and characterizing the transcriptional status of HIV provirus in T cell and macrophage subsets. In addition, we are interested in mechanisms that contribute to HIV associated inflammation. I have served on NIH study sections and special emphasis panels and was a member and chair for the NIH AIDS Molecular and Cellular Biology Study Section. In addition to my research, I have always been proactive in undergraduate and graduate training and I am the current co-Director of the BU PREP post-bac program. I also have organized and participated in programs for international students including a summer program with University of Dammam, Saudi Arabia, a short course at Makerere University in Uganda and a Fogarty International Center training grant with the University of Liberia.
Other Positions
Education
Biomedical Sciences, PhD, University of California, Riverside
Biology, MS, University of California, Riverside
Biology, BS, University of California, Riverside
Publications
Kilroy JM, Leal AA, Henderson AJ. Chronic HIV Transcription, Translation, and Persistent Inflammation. Viruses. 2024 May 09; 16(5). PMID: 38793632.
Published on 2/1/2023Basukala B, Rossi S, Bendiks S, Gnatienko N, Patts G, Krupitsky E, Lioznov D, So-Armah K, Sagar M, Cheng C, Henderson AJ. Virally Suppressed People Living with HIV Who Use Opioids Have Diminished Latency Reversal. Viruses. 2023 Feb 01; 15(2). PMID: 36851631.
Published on 6/28/2022Kuniholm J, Coote C, Henderson AJ. Defective HIV-1 genomes and their potential impact on HIV pathogenesis. Retrovirology. 2022 Jun 28; 19(1):13. PMID: 35764966.
Published on 1/12/2022Dalecki AG, Greer BD, Duverger A, Strange EL, Carlin E, Wagner F, Shi B, Lowman KE, Perez M, Tidwell C, Kaczmarek Michaels K, Giattina S, Bossmann SH, Henderson AJ, Hu H, Kutsch O. Host T Cell Dedifferentiation Effects Drive HIV-1 Latency Stability. J Virol. 2022 03 09; 96(5):e0197421. PMID: 35019721.
Published on 12/28/2021Kuniholm J, Armstrong E, Bernabe B, Coote C, Berenson A, Patalano SD, Olson A, He X, Lin NH, Fuxman Bass JI, Henderson AJ. Intragenic proviral elements support transcription of defective HIV-1 proviruses. PLoS Pathog. 2021 12; 17(12):e1009982. PMID: 34962974.
Published on 11/2/2021Ragan EJ, McCallum C, Marathe J, Cole M, Hofman M, Henderson AJ, Flack T, Miller NS, Burks EJ, Zhao GQ, Denis R, Lin NH, Jacobson KR, Andry CD, Pelton SI, Duffy ER, Bhadelia N. Pandemic Response Requires Research Samples: A U.S. Safety-Net Hospital's Experience and Call for National Action. Ann Intern Med. 2021 12; 174(12):1727-1732. PMID: 34724402.
Published on 3/16/2021Pedro KD, Agosto LM, Sewell JA, Eberenz KA, He X, Fuxman Bass JI, Henderson AJ. A functional screen identifies transcriptional networks that regulate HIV-1 and HIV-2. Proc Natl Acad Sci U S A. 2021 03 16; 118(11). PMID: 33836568.
Published on 12/2/2020Santoso CS, Li Z, Lal S, Yuan S, Gan KA, Agosto LM, Liu X, Pro SC, Sewell JA, Henderson A, Atianand MK, Fuxman Bass JI. Comprehensive mapping of the human cytokine gene regulatory network. Nucleic Acids Res. 2020 12 02; 48(21):12055-12073. PMID: 33179750.
Published on 10/12/2020Olson A, Basukala B, Lee S, Gagne M, Wong WW, Henderson AJ. Targeted Chromatinization and Repression of HIV-1 Provirus Transcription with Repurposed CRISPR/Cas9. Viruses. 2020 10 12; 12(10). PMID: 33053801.
Published on 10/1/2020He X, Eddy JJ, Jacobson KR, Henderson AJ, Agosto LM. Enhanced Human Immunodeficiency Virus-1 Replication in CD4+ T Cells Derived From Individuals With Latent Mycobacterium tuberculosis Infection. J Infect Dis. 2020 10 01; 222(9):1550-1560. PMID: 32417884.
Media Mentions
Published on 3/8/2021
Researchers identify basic mechanisms that regulate HIV expression
Published on 3/1/2020
BUSM Professors Receive $1.4 Million Grant
View full list of 2 media mentions.