Weimin Guo, MD, PhD

Research Assistant Professor (previously held), Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Weimin Guo is a Research Assistant Professor of Pathology & Laboratory Medicine at Boston University Chobanian & Avedisian School of Medicine. His research focuses on how dietary and nutritional interventions influence lifespan and healthspan, with particular emphasis on the mechanisms underlying colon cancer, immune regulation, obesity, and age-related metabolic dysfunction. Recent studies in his lab explore the effects of Mediterranean and plant-rich diets, zinc supplementation, and gut microbiota on tumor development, systemic inflammation, and healthy aging using preclinical models.

Publications

  • Published 3/28/2026

    Guo W, Carretero Santos L, Yee Koh G, Malamy M, Hawley A, Beachy H, Whelpley B, Wang J, Dempsey DR, Crott JW. Identification and characterization of a lipopolysaccharide binding, anti-inflammatory protein from Parabacteroides distasonis. Gut Microbes. 2026 Dec 31; 18(1):2650007. PMID: 41904604.

    Read at: PubMed

  • Published 1/15/2026

    Guo W, Meydani SN, Wu D. Bioactive Phytochemicals in Experimental Models of Multiple Sclerosis: Mechanisms, Efficacy, and Translational Potential. Nutrients. 2026 Jan 15; 18(2). PMID: 41599891.

    Read at: PubMed

  • Published 10/22/2025

    Guo W, Shukitt-Hale B, Wu D, Li L, Meydani SN. Dietary fruits and vegetables mitigate cognitive impairment in mice with high-fat diet-induced obesity: a pilot study. Nutr Neurosci. 2025 Oct 22; 1-10. PMID: 41123496.

    Read at: PubMed

  • Published 2/6/2025

    Guo W, Crossland N, Crott JW. Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice. Exp Mol Pathol. 2025 Mar; 141:104953. PMID: 39919552.

    Read at: PubMed

  • Published 8/21/2024

    Guo W, Wu D, Li L, Lewis ED, Meydani SN. Increased Fruit and Vegetable Consumption Prevents Dysregulated Immune and Inflammatory Responses in High-Fat Diet-Induced Obese Mice. J Nutr. 2024 Oct; 154(10):3144-3150. PMID: 39154866.

    Read at: PubMed

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Websites

Education

  • Shanghai Jiao Tong University, PhD
  • Henan Medical University, MMS/MMSc
  • Henan Medical University, BM/BMus

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