Michael L. Alosco, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Alosco is a licensed clinical neuropsychologist and serves as the co-director of the Boston University Alzheimer’s Disease Research Center Clinical Core and is a lead investigator of the BU CTE Center. He also oversees Neuropsychology for the Memory and Aging Clinic at Boston Medical Center. He completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus on neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. Dr. Alosco completed his post-doctoral studies in neuropsychology via NIH-funded training Awards (T32, F32) at the Boston University Alzheimer’s Disease Research Center and CTE Center. In 2018, he became an Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine and he was promoted to Associate Professor in 2019. Dr. Alosco has >150 peer-reviewed publications, is the PI of multiple NIH funded grants, is the recipient of an NIH/NINDS K23 Award, is the Project Lead of an NIH-funded multisite U54 grant, and serves as aco-investigator on numerous federal and non-federal funded grants. He has also written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders which was published by Oxford University Press in 2019.

Dr. Alosco has an active and established research program that has a thematic focus on three areas: (1) the relationship between repetitive head impacts (RHI) and traumatic brain injury (TBI) with a later-life cognitive and neuropsychiatric decline, as well as neurodegenerative disease(s); (2) the contribution of cerebrovascular disease to the clinical and neuropathological expression of CTE, AD, and AD-related dementias (ADRD); and (3) in vivo biomarker development for CTE, AD, and ADRD with a focus on tau PET imaging, structural MRI, and blood-based biomarkers.

Publications

  • Published 4/22/2025

    Ding H, Madan S, Searls E, McNulty M, Low S, Li Z, Ho K, Rahman S, Igwe A, Popp Z, Hwang PH, De Anda-Duran I, Kolachalama VB, Mez J, Alosco ML, Thomas RJ, Au R, Lin H. Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform. Sleep Med. 2025 Jul; 131:106532. PMID: 40306226.

    Read at: PubMed

  • Published 4/21/2025

    van Amerongen S, Peskind ER, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Alosco ML, Katz D, Banks SJ, Barr WB, Cantu RC, Dodick DW, Geda YE, Mez J, Wethe JV, Weller JL, Daneshvar DH, Palmisano J, Fagle T, Holleck M, Kossow B, Pulukuri S, Tuz-Zahra F, Colasurdo E, Sikkema C, Iliff J, Li G, Shenton ME, Reiman EM, Cummings JL, Stern RA. Catecholamine Dysregulation in Former American Football Players: Findings From the DIAGNOSE CTE Research Project. Neurology. 2025 May 27; 104(10):e213584. PMID: 40258206.

    Read at: PubMed

  • Published 4/9/2025

    Han X, Zhang Y, Petrosky JN, Bald S, Sherva RM, Labadorf A, Cherry JD, Chung J, Farrell K, Abdolmohammadi B, Durape S, Martin BM, Palmisano JN, Farrell JJ, Alvarez VE, Huber BR, Dwyer B, Daneshvar DH, Dams-O'Connor K, Jun GR, Lunetta KL, Goldstein LE, Katz DI, Cantu RC, Shenton ME, Cummings JL, Reiman EM, Stern RA, Alosco ML, Tripodis Y, Farrer LA, Stein TD, Crary JF, McKee AC, Mez J. A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes. Cell Rep Med. 2025 Apr 09; 102084. PMID: 40239644.

    Read at: PubMed

  • Published 4/1/2025

    Cao Y, Salvati LR, Chen J, Ragab A, Mez J, Satizabal CL, Alosco ML, Fang Y, Qiu WQ, Lunetta KL, Murabito JM, Doyle MF. The Association of Circulating Immune Cells with Cognitive Function, Brain Imaging, and Incident all-cause and Alzheimer's Dementia: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2025 Apr 01. PMID: 40168089.

    Read at: PubMed

  • Published 3/28/2025

    Labonte J, Sugarman MA, Pettway E, Zetterberg H, Blennow K, Ashton NJ, Karikari TK, Aparicio HJ, Frank B, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkin I, Farrer LA, Jun GR, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Stern RA, Stein TD, McKee AC, Qiu WQ, Mez J, Banks SJ, Alosco ML. Sex differences on tau, astrocytic, and neurodegenerative plasma biomarkers. J Alzheimers Dis. 2025 Mar 28; 13872877251329468. PMID: 40151917.

    Read at: PubMed

View All 241 Publications:   View Full Profile in BUMC

Websites

Education

  • Kent State University, PhD
  • Kent State University, MA
  • Providence College, BA

View all profiles