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Published 3/12/2025
Goldstein SI, Fan AC, Wang Z, Naineni SK, Cencic R, Garcia-Gutierrez SB, Patel K, Huang S, Brown LE, Emili A, Porco JA. Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays. J Proteome Res. 2025 Apr 04; 24(4):2026-2039. PMID: 40077831.
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Published 2/10/2025
Conley JF, Brown LE, McNeely JH, Pelletier J, Porco JA, Allen KN. Structural Basis for the Improved RNA Clamping of Amidino-Rocaglates to eIF4A1. ACS Omega. 2025 Feb 18; 10(6):5795-5808. PMID: 39989799.
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Published 2/1/2025
Oo A, Borge A, Lee RCH, Salim CK, Wang W, Ricca M, Fong DY, Alonso S, Brown LE, Porco JA, Chu JJH. In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains. J Med Virol. 2025 Feb; 97(2):e70228. PMID: 39921602.
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Published 11/21/2024
Avancha A, Hoyt H, Bhave K, Medeiros M, Cho D, Brown LE, Fernández González D, Porco JA, Forman SA. Glabridin Hypnosis in Zebrafish Larvae Is Associated With Effects on Multiple Anesthetic Target Receptors. Anesth Analg. 2024 Nov 21. PMID: 39773742.
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Published 8/8/2024
Wang Z, Thakare RP, Chitale S, Mishra AK, Goldstein SI, Fan AC, Li R, Zhu LJ, Brown LE, Cencic R, Huang S, Green MR, Pelletier J, Malonia SK, Porco JA. Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells. ACS Cent Sci. 2024 Aug 28; 10(8):1640-1656. PMID: 39220711.