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Published 7/31/2025
Thirman HL, Grider-Hayes MJ, Geben LC, Ihrie RA, Brown LE, Porco JA, Irish JM. Connecting chemical structure to single cell signaling profiles. Commun Biol. 2025 Jul 31; 8(1):1137. PMID: 40745386.
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Published 6/11/2025
Laflamme B, Blackman C, Loranger M, Trilles R, Doytchinova-Weil K, Scully SS, Blackburn JM, Kanegesuku ALG, Roizen JL, Bengtson S, Brown LE, Porco JA, Yoshioka K, Whitesell L, Subramaniam R, Robbins N, Cowen LE. A cationic amphiphilic drug synergizes with strobilurin fungicides to control fungal-borne plant diseases. Cell Chem Biol. 2025 Jun 19; 32(6):872-884.e7. PMID: 40505661.
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Published 3/12/2025
Goldstein SI, Fan AC, Wang Z, Naineni SK, Cencic R, Garcia-Gutierrez SB, Patel K, Huang S, Brown LE, Emili A, Porco JA. Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays. J Proteome Res. 2025 Apr 04; 24(4):2026-2039. PMID: 40077831.
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Published 2/10/2025
Conley JF, Brown LE, McNeely JH, Pelletier J, Porco JA, Allen KN. Structural Basis for the Improved RNA Clamping of Amidino-Rocaglates to eIF4A1. ACS Omega. 2025 Feb 18; 10(6):5795-5808. PMID: 39989799.
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Published 2/1/2025
Oo A, Borge A, Lee RCH, Salim CK, Wang W, Ricca M, Fong DY, Alonso S, Brown LE, Porco JA, Chu JJH. In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains. J Med Virol. 2025 Feb; 97(2):e70228. PMID: 39921602.