Ivana Delalle, MD, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Ivana Delalle is a Professor of Pathology and Laboratory Medicine and Professor of Neurology at Boston University (BU) Chobanian and Avedisian School of Medicine and a Neuropathologist at the Department of Pathology and Laboratory Medicine at Boston Medical Center. Dr. Delalle conducts research bridging basic and clinical science to advance the understanding of the pathogenesis of neurodegenerative diseases. Her present focus, supported by the by National Institutes of Health (NIH) / National Institute of Aging (NIA) is on novel, early, and reliable biomarkers of Alzheimer’s Disease.
Dr. Delalle attended the Zagreb University School of Medicine, Zagreb, Croatia, where she received her MD in 1988 and, in 1992, her PhD in the Developmental Neuroanatomy Laboratory headed by Professor Ivica Kostovic, a pioneer in the understanding of transient layers in the developing human cortex. Dr. Delalle subsequently joined Developmental Neurobiology Laboratory headed by Professor Verne Caviness at Massachusetts General Hospital (MGH) in Boston where she elucidated the expression of cell cycle regulators in relation to the cortical development. After completing her Research Fellowship in Neurology at Harvard Medical School in 1997, Dr. Delalle pursued further postgraduate training as a resident in Anatomic Pathology and Neuropathology in the Department of Pathology at MGH. She became board certified by the American Board of Pathology in Anatomic Pathology and Neuropathology in 2001. Dr. Delalle worked in the teaching hospitals of Harvard Medical School and BU Chobanian and Avedisian School of Medicine as a scientist investigating neurodegenerative and neuropsychiatric diseases, as a neuropathologist with expertise in neurooncology in the clinical arena, and as a teacher and mentor committed to the education of medical students, residents, and neuropathology fellows. Dr. Delalle was the Director of Neuropathology Service at Rhode Island Hospital (2019 -2023) and a Professor of Pathology at Warren Alpert Medical School of Brown University (2020-2023).

Publications

  • Published 3/25/2026

    Pradhan R, Sakib MS, Kaurani L, Krüger DM, Pena T, Burkhardt S, Schütz AL, Kronenberg-Versteeg D, Delalle I, Sananbenesi F, Fischer A. lncRNA Glelr modulates microglia inflammatory programs in association with PU.1. Neurobiol Dis. 2026 May; 222:107366. PMID: 41895620.

    Read at: PubMed

  • Published 3/14/2026

    Pradhan R, Petrovic Z, Sadman Sakib M, Schröder S, Manfred Krüger D, Pena T, Diniz E, Burkhardt S, Schütz AL, Gisa V, Grzadzielewska I, Toischer K, Stein TD, Blusztajn JK, Delalle I, Radulovic J, Sananbenesi F, Fischer A. Neuid: A Novel Neuron-Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease. Adv Sci (Weinh). 2026 May; 13(29):e14972. PMID: 41831315.

    Read at: PubMed

  • Published 11/1/2025

    Pradhan R, Sadman Sakib M, Kaurani L, Krüger DM, Pena T, Burkhardt S, Schütz AL, Kronenberg-Versteeg D, Delalle I, Sananbenesi F, Fischer A. lncRNA 3222401L13Rik/ENSG00000272070 modulates microglial inflammatory programs in association with PU.1. bioRxiv. 2025 Nov 01. PMID: 41278800.

    Read at: PubMed

  • Published 10/9/2025

    Yu D, Germann J, Murtaza G, Hajdarovic KH, Babcock KR, Dehkordi SK, Jackson AC, Delalle I, Orr ME, Zare H, Singh R, Noble WS, Vlassenko AG, Goyal MS, Webb AE. HypoAD: volumetric and single-cell analysis reveals changes in the human hypothalamus in aging and Alzheimer's disease. bioRxiv. 2025 Oct 09. PMID: 41279643.

    Read at: PubMed

  • Published 6/3/2025

    Pradhan R, Petrovic Z, Sakib MS, Schröder S, Krüger DM, Pena T, Diniz E, Burckhardt S, Schütz AL, Grzadzielewska I, Toischer K, Stein TD, Blusztajn JK, Delalle I, Radulovic J, Sananbenesi F, Fischer A. NeuID, a novel neuron-specific lncRNA, resolves a key epigenetic mechanism linking gene silencing to Alzheimer's disease. bioRxiv. 2025 Jun 03. PMID: 40501786.

    Read at: PubMed

View All 65 Publications:   View Full Profile in BUMC

Other Positions

  • Professor, Neurology
    Boston University Chobanian & Avedisian School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University

Websites

Education

  • University of Zagreb, MD
  • University of Zagreb, PhD

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