Ivana Delalle, MD, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Ivana Delalle is a Professor of Pathology and Laboratory Medicine and Professor of Neurology at Boston University (BU) Chobanian and Avedisian School of Medicine and a Neuropathologist at the Department of Pathology and Laboratory Medicine at Boston Medical Center. Dr. Delalle conducts research bridging basic and clinical science to advance the understanding of the pathogenesis of neurodegenerative diseases. Her present focus, supported by the by National Institutes of Health (NIH) / National Institute of Aging (NIA) is on novel, early, and reliable biomarkers of Alzheimer’s Disease.
Dr. Delalle attended the Zagreb University School of Medicine, Zagreb, Croatia, where she received her MD in 1988 and, in 1992, her PhD in the Developmental Neuroanatomy Laboratory headed by Professor Ivica Kostovic, a pioneer in the understanding of transient layers in the developing human cortex. Dr. Delalle subsequently joined Developmental Neurobiology Laboratory headed by Professor Verne Caviness at Massachusetts General Hospital (MGH) in Boston where she elucidated the expression of cell cycle regulators in relation to the cortical development. After completing her Research Fellowship in Neurology at Harvard Medical School in 1997, Dr. Delalle pursued further postgraduate training as a resident in Anatomic Pathology and Neuropathology in the Department of Pathology at MGH. She became board certified by the American Board of Pathology in Anatomic Pathology and Neuropathology in 2001. Dr. Delalle worked in the teaching hospitals of Harvard Medical School and BU Chobanian and Avedisian School of Medicine as a scientist investigating neurodegenerative and neuropsychiatric diseases, as a neuropathologist with expertise in neurooncology in the clinical arena, and as a teacher and mentor committed to the education of medical students, residents, and neuropathology fellows. Dr. Delalle was the Director of Neuropathology Service at Rhode Island Hospital (2019 -2023) and a Professor of Pathology at Warren Alpert Medical School of Brown University (2020-2023).

Publications

  • Published 1/27/2025

    Fischer A, Nho K, Saykin AJ, Delalle I. Response to the Letter, "Circulating small RNAs shed light on dementia risk," by Anthony S. Zannas. Alzheimers Dement. 2025 Feb; 21(2):e14404. PMID: 39868847.

    Read at: PubMed

  • Published 9/18/2024

    Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714. PMID: 39291737.

    Read at: PubMed

  • Published 9/18/2024

    Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A. The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. Alzheimers Dement. 2024 Nov; 20(11):7479-7494. PMID: 39291752.

    Read at: PubMed

  • Published 8/29/2024

    Schröder S, Fuchs U, Gisa V, Pena T, Krüger DM, Hempel N, Burkhardt S, Salinas G, Schütz AL, Delalle I, Sananbenesi F, Fischer A. PRDM16-DT is a novel lncRNA that regulates astrocyte function in Alzheimer's disease. Acta Neuropathol. 2024 Aug 29; 148(1):32. PMID: 39207536.

    Read at: PubMed

  • Published 7/1/2024

    Schröder S, Fuchs U, Gisa V, Pena T, Krüger DM, Hempel N, Burkhardt S, Salinas G, Schütz AL, Delalle I, Sananbenesi F, Fischer A. PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer's Disease. bioRxiv. 2024 Jul 01. PMID: 39005272.

    Read at: PubMed

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Other Positions

  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University

Websites

Education

  • University of Zagreb, MD
  • University of Zagreb, PhD

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