Hugo J. Aparicio, MD, MPH

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Aparicio's research interests include the identification of lifestyle risk factors, biomarkers, neuroimaging markers and genetic influences associated with cerebrovascular diseases. He is particularly interested in the contributions of vascular risk factors to stroke, brain injury and aging, cognitive dysfunction and the development of Alzheimer’s disease and the influence of social determinants of health on these outcomes.

Publications

  • Published 1/19/2026

    Romero JR, Pinheiro A, Demissie S, Aparicio HJ, Lioutas VA, Charidimou A, Beiser A, Ekenze O, Himali JJ, DeCarli C, Seshadri S, Mohammed S. Lifelong trajectories of modifiable vascular risk factors and relation to cerebral small vessel disease in the Framingham Heart Study. medRxiv. 2026 Jan 19. PMID: 41646706.

    Read at: PubMed

  • Published 11/6/2025

    Pinheiro A, Aparicio H, Lioutas VA, Beiser A, Ekenze O, DeCarli C, Seshadri S, Demissie S, Romero JR. Higher Burden of Cerebral Small Vessel Disease Is Associated With Risk of Incident Stroke in Community-Dwelling Individuals. J Am Heart Assoc. 2025 Nov 18; 14(22):e040263. PMID: 41195792.

    Read at: PubMed

  • Published 9/15/2025

    Pinheiro A, Ekenze O, Aparicio HJ, Beiser AS, Decarli CS, Demissie S, Seshadri S, Romero JR. Multimarker Cerebral Small Vessel Disease Score and Risk of Incident Dementia in the Framingham Heart Study. Neurology. 2025 Oct 07; 105(7):e214113. PMID: 40953349.

    Read at: PubMed

  • Published 9/12/2025

    Sheehy S, Aparicio HJ, Delp L, Lioutas VA, Shulman J, Xu NN, Rosenberg L. Association of a History of Preterm Delivery With Stroke Risk in the Black Women's Health Study. Neurology. 2025 Oct; 105(7):e214102. PMID: 40939127.

    Read at: PubMed

  • Published 8/21/2025

    Araujo-Contreras R, Pinheiro AA, Ekenze O, Sisto J, Aparicio HJ, Beiser A, Himali JJ, Lioutas V, DeCarli C, Seshadri S, Demissie S, Romero JR. Multi-marker cerebral small vessel disease score and risk of incident depression: The Framingham Heart Study. J Affect Disord. 2026 Jan 01; 392:120089. PMID: 40848767.

    Read at: PubMed

View All 103 Publications:   View Full Profile in BUMC

Other Positions

  • Investigator
    Framingham Heart Study

Websites

Education

  • University of Pennsylvania School of Medicine, MD
  • Harvard School of Public Health, MPH
  • Emory University, BA

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