Haiyan Gong, MD, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Glaucoma is a leading cause of blindness worldwide. A primary risk factor for the development and progression of primary open-angle glaucoma (POAG) is elevation of intraocular pressure (IOP), which resulted from increased aqueous outflow resistance. However, the cause of this elevated aqueous outflow resistance in POAG remains unknown. The research in our laboratory is focused on understanding the mechanisms that regulate aqueous humor outflow resistance in normal eyes and how this resistance is increased in POAG in order to provide new insights for developing new therapeutic strategies to lower IOP.

Publications

  • Published 12/2/2024

    Acott TS, Fautsch MP, Mao W, Ethier CR, Huang AS, Kelley MJ, Aga M, Bhattacharya SK, Borras T, Bovenkamp D, Chowdhury UR, Clark AF, Dibas MI, Du Y, Elliott MH, Faralli JA, Gong H, Herberg S, Johnstone MA, Kaufman PL, Keller KE, Kelly RA, Krizaj D, Kuehn MH, Li HL, Lieberman R, Lin SC, Liu Y, McDonnell FS, McDowell CM, McLellan GJ, Mzyk P, Nair KS, Overby DR, Peters DM, Raghunathan V, Rao PV, Roddy GW, Sharif NA, Shim MS, Sun Y, Thomson BR, Toris CB, Willoughby CE, Zhang HF, Freddo TF, Fuchshofer R, Hill KR, Karimi A, Kizhatil K, Kopcyznski CC, Liton P, Patel G, Peng M, Pattabiraman PP, Prasanna G, Reina-Torres E, Samples EG, Samples JR, Steel CL, Strohmaier CA, Subramanian P, Sugali CK, van Batenburg-Sherwood J, Wong C, Youngblood H, Zode GS, White E, Stamer WD. Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Invest Ophthalmol Vis Sci. 2024 Dec 02; 65(14):32. PMID: 39693082.

    Read at: PubMed

  • Published 11/29/2024

    Karimi A, Razaghi R, Stanik A, Daniel D'costa S, Mirafzal I, Kelley MJ, Acott TS, Gong H. High-resolution modeling of aqueous humor dynamics in the conventional outflow pathway of a normal human donor eye. Comput Methods Programs Biomed. 2025 Mar; 260:108538. PMID: 39644783.

    Read at: PubMed

  • Published 10/1/2024

    Chung YG, Fan S, Gulati V, Li HL, Gong H, Toris CB, Prausnitz MR, Ethier CR. IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space. Transl Vis Sci Technol. 2024 Oct 01; 13(10):14. PMID: 39377753.

    Read at: PubMed

  • Published 4/17/2024

    Karimi A, Aga M, Khan T, D'costa SD, Thaware O, White E, Kelley MJ, Gong H, Acott TS. Comparative analysis of traction forces in normal and glaucomatous trabecular meshwork cells within a 3D, active fluid-structure interaction culture environment. Acta Biomater. 2024 May; 180:206-229. PMID: 38641184.

    Read at: PubMed

  • Published 12/1/2023

    Li HL, Ren R, Gong H. Segmental Unconventional Outflow in Mouse Eyes. Invest Ophthalmol Vis Sci. 2023 Dec 01; 64(15):26. PMID: 38117243.

    Read at: PubMed

View All 92 Publications:   View Full Profile in BUMC

Other Positions

  • Professor, Anatomy & Neurobiology
    Boston University Chobanian & Avedisian School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Nanchang University, MD
  • Boston University School of Medicine, PhD
  • Peking Union Medical College, MS

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