Esther Landesman, PhD

Instructor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Landesman's research has focused on studying the role of protein kinase CK2, a highly conserved and constitutively expressed serine-threonine kinase. In vitro and transgenic mouse models were used to study the role of CK2 in breast tumorigenesis and the synergism of CK2 with the absence of p53 in lymphoma development. Genetic disruption of the catalytic subunits of CK2: CK2a and CK2a’ have uncovered the impact of CK2 in mouse embryonic development. Current research attempts to characterize the consequences of compounded reduction of CK2 catalytic subunits in mice. In addition, Dr. Landesman is collaborating with Dr. Hui Feng to find targetable vulnerabilities in MYC-related cancers. Dr. Landesman-Bollag obtained her PhD and did her postdoctoral training at Chobanian and Avedisian School of Medicine in the laboratory of the late Dr. David Seldin. She is Instructor of Hematology & Medical Oncology at Chobanian and Avedisian School of Medicine.

Publications

  • Published 7/15/2024

    Sicinska E, Kola VSR, Kerfoot JA, Taddei ML, Al-Ibraheemi A, Hsieh YH, Church AJ, Landesman-Bollag E, Landesman Y, Hemming ML. ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs. Cancer Res. 2024 Jul 15; 84(14):2247-2264. PMID: 38657118.

    Read at: PubMed

  • Published 2/7/2024

    Xiao B, Landesman-Bollag E, Feng H. What value do zebrafish have to anticancer drug discovery? Expert Opin Drug Discov. 2024 Apr; 19(4):369-375. PMID: 38327017.

    Read at: PubMed

  • Published 1/15/2022

    Wang Q, Feng L, Zhang H, Gao J, Mao C, Landesman-Bollag E, Mostoslavsky G, Lunderberg JM, Zheng W, Hao S, Gao W. Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test. Antib Ther. 2022 Jan; 5(1):55-62. PMID: 35146332.

    Read at: PubMed

  • Published 9/23/2021

    Shibad V, Bootwala A, Mao C, Bader H, Vo H, Landesman-Bollag E, Guo C, Rubio A, Near R, Gao W, Challa S, Chukka V, Gao J, Kelly A, Landesman T, VanHelene T, Zhong X. L2pB1 Cells Contribute to Tumor Growth Inhibition. Front Immunol. 2021; 12:722451. PMID: 34630396.

    Read at: PubMed

  • Published 5/1/2021

    Zhou Y, Lian H, Shen N, Korm S, Kwok Ping Lam A, Layton O, Huiting LN, Li D, Miao K, Zeng A, Landesman-Bollag E, Seldin DC, Fu H, Hong L, Feng H. The multifaceted role of protein kinase CK2 in high-risk acute lymphoblastic leukemia. Haematologica. 2021 05 01; 106(5):1461-1465. PMID: 32817283.

    Read at: PubMed

View All 31 Publications:   View Full Profile in BUMC

Websites

Education

  • Boston University, PhD
  • The Hebrew University of Jerusalem, MS
  • The Hebrew University of Jerusalem, BS

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