Weiming Xia, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Xia completed his graduate studies at the University of Texas Medical School at Houston where he earned his MS and PhD degrees (Biochemistry and Molecular Biology). He completed his postdoctoral training in Alzheimer’s disease (AD) at Brigham and Women’s Hospital, Harvard Medical School. In 1999 he became Assistant Professor of Neurology at Harvard Medical School and established a NIH-funded research lab to study AD. In 2012 he joined Department of Veterans Affairs Bedford VA Medical Center, and he leads an independent lab to explore molecular mechanism and biomarkers for AD.

Dr. Xia’s research interests involve target identification, characterization, validation and early stage drug development, with exploration of clinical biomarkers for AD. He has established multiple platforms to quantify pathological proteins like amyloid ß protein (Aß), Tau, neuroinflammatory factors, and related biomarkers. He also develops Mass Spectrometry-based analytic approaches to explore biomarkers for AD and other central nervous system disorders.

Publications

  • Published 8/6/2025

    Ness S, Sampani K, Tuz-Zahra F, Aytan N, Alluri S, Fiorello MG, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML. Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease. Sci Rep. 2025 Aug 06; 15(1):28720. PMID: 40770000.

    Read at: PubMed

  • Published 5/6/2025

    Berlowitz D, Wang Y, Reisman J, Miller D, Morin PJ, Arasa VCA, Mittler B, Zhang R, Tahami Monfared AA, Irizarry M, Zhang Q, Xia W. Feasibility of Identifying Acute Nontraumatic Intracerebral Hemorrhage Events Using Diagnostic Coding Among Veterans with Mild Cognitive Impairment or Alzheimer's Dementia. Neurol Ther. 2025 Aug; 14(4):1287-1298. PMID: 40325265.

    Read at: PubMed

  • Published 4/16/2025

    Mittler B, Cambi X, Biskach M, Reisman J, Wang Y, Berlowitz D, Morin P, Miller DR, Brandao-Viruet K, Clare SJ, Xia KZ, Tahami Monfared AA, Irizarry M, Zhang Q, Xia W. Patient journey and decision processes for anti-amyloid therapy in Alzheimer's disease. J Neurol. 2025 Apr 16; 272(5):341. PMID: 40237866.

    Read at: PubMed

  • Published 10/20/2023

    Collu R, Giunti E, Daley S, Chen M, Xia W. Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice. Biomed Pharmacother. 2023 Dec; 168:115756. PMID: 37865996.

    Read at: PubMed

  • Published 9/25/2023

    Aguilar BJ, Miller D, Jasuja G, Li X, Shishova E, O'Connor MK, Nguyen A, Morin P, Berlowitz D, Zhang R, Monfared AAT, Zhang Q, Xia W. Rule-Based Identification of Individuals with Mild Cognitive Impairment or Alzheimer's Disease Using Clinical Notes from the United States Veterans Affairs Healthcare System. Neurol Ther. 2023 Dec; 12(6):2067-2078. PMID: 37747662.

    Read at: PubMed

View All 131 Publications:   View Full Profile in BUMC

Websites

Education

  • University of Texas Health Science Center at Houston, PhD
  • University of Texas Health Science Center at Houston, MS
  • Fudan University, BS

View all profiles