Victoria M. Bolotina, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Bolotina, Ph.D., is a leading expert in Calcium signaling and ion channels (with over 2000 citations of her work), who is well funded by NIH. The focus of her research is on the molecular mechanisms of Calcium entry and its role in physiological and pathological function.

Publications

  • Published 6/1/2016

    Cohen RA, Murdoch CE, Watanabe Y, Bolotina VM, Evangelista AM, Haeussler DJ, Smith MD, Mei Y, Tong X, Han J, Behring JB, Bachschmid MM, Matsui R. Endothelial Cell Redox Regulation of Ischemic Angiogenesis. J Cardiovasc Pharmacol. 2016 Jun; 67(6):458-64. PMID: 26927696.

    Read at: PubMed

  • Published 1/12/2016

    Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016; 7:10332. PMID: 26755131.

    Read at: PubMed

  • Published 6/11/2014

    Thompson MD, Mei Y, Weisbrod RM, Silver M, Shukla PC, Bolotina VM, Cohen RA, Tong X. Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery. J Biol Chem. 2014 Jul 18; 289(29):19907-16. PMID: 24920669.

    Read at: PubMed

  • Published 10/23/2012

    Evangelista AM, Thompson MD, Bolotina VM, Tong X, Cohen RA. Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration. Free Radic Biol Med. 2012 Dec 15; 53(12):2327-34. PMID: 23089226.

    Read at: PubMed

  • Published 10/5/2012

    Schäfer C, Rymarczyk G, Ding L, Kirber MT, Bolotina VM. Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration. J Biol Chem. 2012 Nov 23; 287(48):40745-57. PMID: 23043102.

    Read at: PubMed

Other Positions

  • Research Professor, Pharmacology, Physiology & Biophysics
    Boston University Chobanian & Avedisian School of Medicine
  • Member, Whitaker Cardiovascular Institute
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Moscow State University, PhD
  • Moscow State University, BSc