Nicole L Spartano, PhD
Assistant Professor, Medicine
Biography
Nicole Spartano, PhD is an Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Chobanian and Avedisian School of Medicine. She serves as the Director of the Glucose Monitoring Station at the Framingham Heart Study. This study is funded through an R01 from the National Institute of Diabetes and Digestive and Kidney Diseases (Spartano, PI) to use continuous glucose monitors in a non-diabetic population to measure glucose patterns that may predict the development of diabetes. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer’s Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer’s disease.
Dr. Spartano also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.
Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.
Other Positions
- Investigator, Framingham Heart Study
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Websites
Education
- Tufts University, PhD
- Tufts University, MS
- Syracuse University, BS
Publications
- Published on 3/11/2025
Alexanian SM, Cheney MC, Bello Ramos JC, Spartano NL, Wolpert HA, Steenkamp DW. Impact of Meal Insulin Bolus Timing and Bedtime Snacking on Continuous Glucose Monitoring-Derived Glycemic Metrics in Hospitalized Inpatients. Diabetes Technol Ther. 2025 Mar 11. PMID: 40067436.
Read at: PubMed - Published on 2/12/2025
Spartano NL, Prescott B, Walker ME, Shi E, Venkatesan G, Fei D, Lin H, Murabito JM, Ahn D, Battelino T, Edelman SV, Fleming GA, Freckmann G, Galindo RJ, Joubert M, Lansang MC, Mader JK, Mankovsky B, Mathioudakis NN, Mohan V, Peters AL, Shah VN, Spanakis EK, Waki K, Wright EE, Zilbermint M, Wolpert HA, Steenkamp DW. Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes. J Diabetes Sci Technol. 2025 Feb 12; 19322968251315171. PMID: 39936548.
Read at: PubMed - Published on 12/4/2024
Alexanian SM, Cheney MC, Spartano NL, Bello-Ramos JC, Reddy N, Malik A, Murati J, Wolpert HA, Steenkamp DW. Comparing Postprandial Glycemic Control Using Fiasp vs Insulin Aspart in Hospitalized Patients With Type 2 Diabetes. Endocr Pract. 2025 Mar; 31(3):306-314. PMID: 39643003.
Read at: PubMed - Published on 10/6/2024
Klonoff DC, Freckmann G, Pleus S, Kovatchev BP, Kerr D, Tse CC, Li C, Agus MSD, Dungan K, Voglová Hagerf B, Krouwer JS, Lee WA, Misra S, Rhee SY, Sabharwal A, Seley JJ, Shah VN, Tran NK, Waki K, Worth C, Tian T, Aaron RE, Rutledge K, Ho CN, Ayers AT, Adler A, Ahn DT, Aktürk HK, Al-Sofiani ME, Bailey TS, Baker M, Bally L, Bannuru RR, Bauer EM, Bee YM, Blanchette JE, Cengiz E, Chase JG, Y Chen K, Cherñavvsky D, Clements M, Cote GL, Dhatariya KK, Drincic A, Ejskjaer N, Espinoza J, Fabris C, Fleming GA, Gabbay MAL, Galindo RJ, Gómez-Medina AM, Heinemann L, Hermanns N, Hoang T, Hussain S, Jacobs PG, Jendle J, Joshi SR, Koliwad SK, Lal RA, Leiter LA, Lind M, Mader JK, Maran A, Masharani U, Mathioudakis N, McShane M, Mehta C, Moon SJ, Nichols JH, O'Neal DN, Pasquel FJ, Peters AL, Pfützner A, Pop-Busui R, Ranjitkar P, Rhee CM, Sacks DB, Schmidt S, Schwaighofer SM, Sheng B, Simonson GD, Sode K, Spanakis EK, Spartano NL, Umpierrez GE, Vareth M, Vesper HW, Wang J, Wright E, Wu AHB, Yeshiwas S, Zilbermint M, Kohn MA. The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. J Diabetes Sci Technol. 2024 Nov; 18(6):1346-1361. PMID: 39369312.
Read at: PubMed - Published on 9/11/2024
Spartano NL, Sultana N, Lin H, Cheng H, Lu S, Fei D, Murabito JM, Walker ME, Wolpert HA, Steenkamp DW. Defining continuous glucose monitor time in range in a large community-based cohort without diabetes. J Clin Endocrinol Metab. 2024 Sep 11. PMID: 39257191.
Read at: PubMed - Published on 7/24/2024
Spartano NL, Zhang Y, Liu C, Chernofsky A, Lin H, Trinquart L, Borrelli B, Pathiravasan CH, Kheterpal V, Nowak C, Vasan RS, Benjamin EJ, McManus DD, Murabito JM. Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study. JMIR Biomed Eng. 2024 Jul 24; 9:e54631. PMID: 39047284.
Read at: PubMed - Published on 6/24/2024
Grech J, Nkambule BB, Thibord F, Chan MV, Lachapelle AR, Vasan R, Spartano NL, Chen MH, Nayor M, Lewis GD, Johnson AD. Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity. Med Sci Sports Exerc. 2024 Nov 01; 56(11):2195-2202. PMID: 38913957.
Read at: PubMed - Published on 6/13/2024
Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676. PMID: 38870519.
Read at: PubMed - Published on 6/3/2024
Alver SK, Pan S, Mossavar-Rahmani Y, Sotres-Alvarez D, Evenson KR, Floyd JS, Xanthakis V, Lin J, Cuthbertson C, Gallo LC, Cai J, Penedo FJ, Llabre MM, Matsushita K, Talavera GA, Pirzada A, Spartano N, Daviglus ML, Vasan RS, Kaplan RC. Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults. JAMA Netw Open. 2024 Jun 03; 7(6):e2415094. PMID: 38842811.
Read at: PubMed - Published on 1/1/2024
Gonzales MM, Kojis D, Spartano NL, Thibault EG, DeCarli CS, El Fakhri G, Johnson KA, Beiser AS, Seshadri S. Associations of Physical Activity Engagement with Cerebral Amyloid-ß and Tau from Midlife. J Alzheimers Dis. 2024; 100(3):935-943. PMID: 39031362.
Read at: PubMed
View 61 more publications: View full profile at BUMC