Karen M. Harnett, PhD
Assistant Professor, Pharmacology, Physiology & Biophysics
Biography
Karen Harnett, PhD, is an Assistant Professor of Pharmacology & Experimental Therapeutics at Chobanian and Avedisian School of Medicine. After completing her postdoc at the University of Rhode Island, she remained in state to teach at Brown University. Over a decade later, she arrived at Boston University. While at Brown University, she earned 10 awards for her teaching and is currently the co-director of Disease and Therapy (DRx) course for second year MD curriculum of Chobanian and Avedisian School of Medicine. She is a member of the American Society for Pharmacology and Experimental Therapeutics and the American Gastroenterological Association. While a member of the American Gastroenterological Association, she has given 10 presentations in the course of her career.
Education
- Boston University School of Medicine, PhD
- Providence College, BS
Classes Taught
- GMSPS719
Publications
- Published on 1/28/2014
Rieder F, Nonevski I, Ma J, Ouyang Z, West G, Protheroe C, DePetris G, Schirbel A, Lapinski J, Goldblum J, Bonfield T, Lopez R, Harnett K, Lee J, Hirano I, Falk G, Biancani P, Fiocchi C. T-helper 2 cytokines, transforming growth factor ß1, and eosinophil products induce fibrogenesis and alter muscle motility in patients with eosinophilic esophagitis. Gastroenterology. 2014 May; 146(5):1266-77.e1-9. PMID: 24486052.
Read at: PubMed - Published on 7/12/2012
Ma J, Altomare A, Guarino M, Cicala M, Rieder F, Fiocchi C, Li D, Cao W, Behar J, Biancani P, Harnett KM. HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1; 303(5):G635-45. PMID: 22790593.
Read at: PubMed - Published on 6/26/2012
Altomare A, Ma J, Guarino MP, Cheng L, Rieder F, Ribolsi M, Fiocchi C, Biancani P, Harnett K, Cicala M. Platelet-activating factor and distinct chemokines are elevated in mucosal biopsies of erosive compared with non-erosive reflux disease patients and controls. Neurogastroenterol Motil. 2012 Oct; 24(10):943-e463. PMID: 22734465.
Read at: PubMed - Published on 9/29/2011
Ma J, Altomare A, Rieder F, Behar J, Biancani P, Harnett KM. ATP: a mediator for HCl-induced TRPV1 activation in esophageal mucosa. Am J Physiol Gastrointest Liver Physiol. 2011 Dec; 301(6):G1075-82. PMID: 21960521.
Read at: PubMed - Published on 9/1/2011
Orlando RC, Paterson WG, Harnett KM, Ma J, Behar J, Biancani P, Guarino MP, Altomare A, Cicala M, Cao W. Esophageal disease: updated information on inflammation. Ann N Y Acad Sci. 2011 Sep; 1232:369-75. PMID: 21950828.
Read at: PubMed - Published on 10/30/2010
Harnett KM, Rieder F, Behar J, Biancani P. Viewpoints on Acid-induced inflammatory mediators in esophageal mucosa. J Neurogastroenterol Motil. 2010 Oct; 16(4):374-88. PMID: 21103419.
Read at: PubMed - Published on 7/8/2010
Ma J, Altomare A, de la Monte S, Tong M, Rieder F, Fiocchi C, Behar J, Shindou H, Biancani P, Harnett KM. HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H2O2 by peripheral blood leukocytes. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G791-8. PMID: 20616304.
Read at: PubMed - Published on 5/6/2010
Guarino MP, Cheng L, Ma J, Harnett K, Biancani P, Altomare A, Panzera F, Behar J, Cicala M. Increased TRPV1 gene expression in esophageal mucosa of patients with non-erosive and erosive reflux disease. Neurogastroenterol Motil. 2010 Jul; 22(7):746-51, e219. PMID: 20456759.
Read at: PubMed - Published on 3/18/2010
Rieder F, Biancani P, Harnett K, Yerian L, Falk GW. Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis. Am J Physiol Gastrointest Liver Physiol. 2010 May; 298(5):G571-81. PMID: 20299604.
Read at: PubMed - Published on 12/3/2009
Ma J, Harnett KM, Behar J, Biancani P, Cao W. Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2010 Feb; 298(2):G233-40. PMID: 19959817.
Read at: PubMed
View 36 more publications: View full profile at BUMC