Diana F. Clarke, PharmD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Diana Clarke, Pharm.D., is an Assistant Professor of Pediatrics in Infectious Diseases at the Chobanian and Avedisian School of Medicine and Pediatric HIV Pharmacotherapy Specialist at Boston Medical Center. She works in the Pediatric ID clinic and the High-Risk OB clinic where she is actively involved in the management of children and pregnant women living with HIV. Her commitment to pediatrics is demonstrated through her memberships to the WHO Pediatric Antiretroviral Working Group and as a Consultant, Human Resources and Services Administration, HIV/AIDS Bureau (HRSA) for the DHHS Pediatric and Perinatal HIV Guidelines Committees. Her research interests include neonatal pharmacokinetics of antiretroviral agents and pharmacokinetics of anti-infectives in pregnant women. She is currently Chair of several IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials Network, NIH) protocols and a member of the IMPAACT Scientific Treatment Committee.

Publications

  • Published 1/20/2025

    Rozen Eisenberg I, Campbell JI, Clarke D, Cooper ER, Pelton SI, Vuppula SS. Practice Variability in Uptake and Implementation of New U.S. DHHS Guidelines for Feeding of HIV-Exposed Infants. J Pediatric Infect Dis Soc. 2025 Jan 20; 14(1). PMID: 39726301.

    Read at: PubMed

  • Published 10/16/2024

    Brooks KM, Baltrusaitis K, Clarke DF, Nachman S, Jao J, Purswani MU, Agwu A, Beneri C, Deville JG, Powis KM, Stek AM, Eke AC, Shapiro DE, Capparelli E, Greene E, George K, Yin DE, Jean-Philippe P, Chakhtoura N, Bone F, Bacon K, Johnston B, Reding C, Kersey K, Humeniuk R, Best BM, Mirochnick M, Momper JD. Pharmacokinetics and Safety of Remdesivir in Pregnant and Nonpregnant Women With COVID-19: Results From IMPAACT 2032. J Infect Dis. 2024 Oct 16; 230(4):878-888. PMID: 38839047.

    Read at: PubMed

  • Published 10/1/2024

    Bekker A, Capparelli EV, Mirochnick M, Clarke DF, Cotton MF, Shapiro R, McCarthy K, Moye J, Violari A, Chokephaibulkit K, Abrams E, Penazzato M, Ruel TD, Cressey TR. Lamivudine dosing for preterm infants exposed to HIV: a population pharmacokinetic modelling and simulation study. J Antimicrob Chemother. 2024 Oct 01; 79(10):2570-2574. PMID: 39092932.

    Read at: PubMed

  • Published 12/18/2022

    Liu XI, Dallmann A, Brooks K, Best BM, Clarke DF, Mirochnick M, van den Anker JN, Capparelli EV, Momper JD. Physiologically-based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID-19. CPT Pharmacometrics Syst Pharmacol. 2023 Feb; 12(2):148-153. PMID: 36479969.

    Read at: PubMed

  • Published 1/1/2022

    Piscitelli J, Nikanjam M, Best BM, Acosta E, Mirochnick M, Clarke DF, Capparelli EV, Momper JD. Optimizing Dolutegravir Initiation in Neonates Using Population Pharmacokinetic Modeling and Simulation. J Acquir Immune Defic Syndr. 2022 01 01; 89(1):108-114. PMID: 34629412.

    Read at: PubMed

Education

  • State University of New York at Buffalo, PharmD
  • University of Rhode Island College of Pharmacy, BS