Deborah Jean Anderson, PhD
Professor, Medicine
Biography
I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.
Other Positions
- Professor, Other OB/GYN, Obstetrics & Gynecology, Boston University Chobanian & Avedisian School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- University of Texas at Austin, PhD
- University of Texas at Austin, MS
- Rice University, BA
Publications
- Published on 2/5/2025
Dohadwala S, Shah P, Farrell M, Politch J, Marathe J, Costello CE, Anderson DJ. Sialidases derived from Gardnerella vaginalis remodel the sperm glycocalyx and impair sperm function. bioRxiv. 2025 Feb 05. PMID: 39975358.
Read at: PubMed - Published on 10/22/2024
Nador E, Mausser E, Marathe JG, Politch JA, Thurman AR, Whaley KJ, Anderson DJ. Antibody-dependent complement-mediated sperm cytotoxicity in the endocervix is a dominant contraceptive mechanism of ZB-06 vaginal film. Fertil Steril. 2025 Mar; 123(3):534-536. PMID: 39447830.
Read at: PubMed - Published on 7/25/2024
Johnson JA, Li JF, Politch JA, Lipscomb JT, Tino AS, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen Under Integrase Strand Transfer Inhibitor-Based Therapy Are Largely Myeloid Cell-Derived and Disparate. J Infect Dis. 2024 Jul 25; 230(1):78-85. PMID: 39052738.
Read at: PubMed - Published on 3/6/2024
Nador E, Xia C, Santangelo PJ, Whaley KJ, Costello CE, Anderson DJ. Platform-Specific Fc N-Glycan Profiles of an Antisperm Antibody. Antibodies (Basel). 2024 Mar 06; 13(1). PMID: 38534207.
Read at: PubMed - Published on 2/13/2024
Johnson JA, Li JF, Politch JA, Lipscomb JT, Santos Tino A, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen under INSTI-based Therapy are Largely Myeloid Cell-Derived and Disparate from Circulating Provirus. J Infect Dis. 2024 Feb 13. PMID: 38356153.
Read at: PubMed - Published on 1/9/2024
Dohadwala S, Geib MT, Politch JA, Anderson DJ. Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy. Front Reprod Health. 2023; 5:1337479. PMID: 38264184.
Read at: PubMed - Published on 6/13/2023
Dohadwala S, Politch JA, Barmine JH, Anderson DJ. A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products. Open Access J Contracept. 2023; 14:83-94. PMID: 37332341.
Read at: PubMed - Published on 4/13/2023
Anderson DJ, Johnston DS. A brief history and future prospects of contraception. Science. 2023 Apr 14; 380(6641):154-158. PMID: 37053322.
Read at: PubMed - Published on 3/30/2023
Mausser E, Nador E, Politch JA, Pauly MR, Marathe JG, Moench TR, Zeitlin L, Whaley KJ, Anderson DJ. LALAPG variant of the Human Contraception Antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity. PLoS One. 2023; 18(3):e0282147. PMID: 36996137.
Read at: PubMed - Published on 3/2/2023
Thurman AR, Moench TR, Hoke M, Politch JA, Cabral H, Mausser E, Nador E, Morton J, Hamorsky K, Swope K, Bratcher B, Anderson DJ, Whaley KJ. ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study. Am J Obstet Gynecol. 2023 Jun; 228(6):716.e1-716.e12. PMID: 36870409.
Read at: PubMed
View 296 more publications: View full profile at BUMC