Caroline M. Apovian, MD
Professor, Medicine
Biography
Dr. Apovian’s focus is on clinical research in obesity and diabetes. Her group investigates weight loss and its effects on endothelial cell function, adipose cell metabolism and inflammation, research in the bariatric surgery population and novel pharmacotherapeutic antiobesity agents. She has become an expert in the technique for subcutaneous adipose tissue aspirations, and has been performing these aspirations on research subjects at Boston University for over 5 years. Other research projects include dietary and physical activity interventions in underserved post-partum women and the investigation into the effects of increased dietary protein on lean body mass, maximal voluntary muscle strength and power in older men with mobility limitations.
Other Positions
- Professor, Diabetes & Endocrinology, Pediatrics, Boston University School of Medicine
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
- Active Staff Privileges, Endocrinology, Diabetes, Nutrition & Weight Management, Medicine, Boston Medical Center
Education
- University of Medicine and Dentistry of New Jersey, MD
- Barnard College, BA
Publications
- Published on 8/1/2019
Nicholas DA, Proctor EA, Agrawal M, Belkina AC, Van Nostrand SC, Panneerseelan-Bharath L, Jones AR, Raval F, Ip BC, Zhu M, Cacicedo JM, Habib C, Sainz-Rueda N, Persky L, Sullivan PG, Corkey BE, Apovian CM, Kern PA, Lauffenburger DA, Nikolajczyk BS. Fatty Acid Metabolites Combine with Reduced ß Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes. Cell Metab. 2019 Sep 03; 30(3):447-461.e5. PMID: 31378464.
Read at: PubMed - Published on 6/1/2019
Karki S, Farb MG, Sharma VM, Jash S, Zizza EJ, Hess DT, Carmine B, Carter CO, Pernar LI, Apovian CM, Puri V, Gokce N. Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity. J Am Heart Assoc. 2019 Jun 04; 8(11):e011431. PMID: 31433737.
Read at: PubMed - Published on 5/13/2019
Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Martinez JA, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM. Erratum: A Randomized, Double-Blind, Placebo-Controlled Study of Gelesis100: A Novel Nonsystemic Oral Hydrogel for Weight Loss. Obesity (Silver Spring). 2019 Jul; 27(7):1210. PMID: 31231960.
Read at: PubMed - Published on 5/2/2019
Thompson CC, Abu Dayyeh BK, Kushnir V, Kushner RF, Jirapinyo P, Schorr AB, Aronne LJ, Amaro A, Jaffe DL, Schulman AR, Early D, Stein AC, Sharaiha R, Edmundowicz SA, Bohning JM, Jensen MD, Shukla AP, Apovian C, Kim DW, Tran D, Zarrinpar A, Ryan MB, Young M, Lowe A, Haas M, Goldsmith H, McCrea J, Sullivan S. Aspiration therapy for the treatment of obesity: 4-year results of a multicenter randomized controlled trial. Surg Obes Relat Dis. 2019 Aug; 15(8):1348-1354. PMID: 31302000.
Read at: PubMed - Published on 5/1/2019
Wee CC, Fleishman A, McCarthy AC, Hess DT, Apovian C, Jones DB. Decision Regret up to 4 Years After Gastric Bypass and Gastric Banding. Obes Surg. 2019 May; 29(5):1624-1631. PMID: 30796614.
Read at: PubMed - Published on 4/2/2019
Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 Apr 02; 8(7):e011100. PMID: 30929550.
Read at: PubMed - Published on 3/22/2019
Fujioka K, Malhotra M, Perdomo C, Apovian CM. Effect of lorcaserin in different age groups: a post hoc analysis of patients from the BLOOM, BLOSSOM and BLOOM-DM studies. Obes Sci Pract. 2019 Apr; 5(2):120-129. PMID: 31019729.
Read at: PubMed - Published on 3/20/2019
Godfrey C, Bremer A, Alba D, Apovian C, Koethe JR, Koliwad S, Lewis D, Lo J, McComsey GA, Eckard A, Srinivasa S, Trevillyan J, Palmer C, Grinspoon S. Obesity and Fat Metabolism in HIV-infected Individuals: Immunopathogenic Mechanisms and Clinical Implications. J Infect Dis. 2019 Mar 20. PMID: 30893434.
Read at: PubMed - Published on 3/5/2019
Tsai AG, Apovian C, Kaplan L. Weight Loss Interventions in Adults. JAMA. 2019 03 05; 321(9):900. PMID: 30835301.
Read at: PubMed - Published on 2/1/2019
Srivastava G, Fox CK, Kelly AS, Jastreboff AM, Browne AF, Browne NT, Pratt JSA, Bolling C, Michalsky MP, Cook S, Lenders CM, Apovian CM. Clinical Considerations Regarding the Use of Obesity Pharmacotherapy in Adolescents with Obesity. Obesity (Silver Spring). 2019 Feb; 27(2):190-204. PMID: 30677262.
Read at: PubMed
View 177 more publications: View full profile at BUMC