Dr.Koo’s research interests span the areas of neuroimaging, particularly the development of multi-modal magnetic resonance imaging (MRI) and analysis methods. Neuroimaging commonly aims to identify difference between healthy and unhealthy brains in a quantitative way. However, due to the complexity of the human brain, it is extremely difficult to analyze early stage or slow disease progressions from visually inspecting the image. Dr.Koo’s work focuses on developing novel imaging protocols and mapping methods with better sensitivities on monitoring neurological and functional changes in the brain. Dr.Koo also serves as an imaging core director at National Emerging Infectious Disease Laboratories (NEIDL). The goal is to develop multimodal imaging protocol that allows in-vivo monitoring on different stages of tissue inflammatory/immune responses.
- Faculty, National Emerging Infectious Disease Lab, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
- Hanyang University, PhD
- Hanyang University, MS
- Hanyang University, BS
- Published on 5/8/2020
Guo W, Koo BB, Kim JH, Bhadelia RA, Seo DW, Hong SB, Joo EY, Lee S, Lee JI, Cho KR, Shon YM. Defining the optimal target for anterior thalamic deep brain stimulation in patients with drug-refractory epilepsy. J Neurosurg. 2020 May 08; 1-10. PMID: 32384279.
- Published on 10/17/2019
Naeser MA, Ho MD, Martin PI, Hamblin MR, Koo BB. Increased Functional Connectivity Within Intrinsic Neural Networks in Chronic Stroke Following Treatment with Red/Near-Infrared Transcranial Photobiomodulation: Case Series with Improved Naming in Aphasia. Photobiomodul Photomed Laser Surg. 2020 Feb; 38(2):115-131. PMID: 31621498.
- Published on 7/4/2018
Koo BB, Calderazzo S, Bowley BGE, Kolli A, Moss MB, Rosene DL, Moore TL. Long-term effects of curcumin in the non-human primate brain. Brain Res Bull. 2018 09; 142:88-95. PMID: 29981358.
- Published on 8/4/2017
Koo BB, Michalovicz LT, Calderazzo S, Kelly KA, Sullivan K, Killiany RJ, O'Callaghan JP. Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness. Brain Behav Immun. 2018 Jan; 67:42-46. PMID: 28782715.
- Published on 7/10/2017
Farrar DC, Mian AZ, Budson AE, Moss MB, Koo BB, Killiany RJ. Retained executive abilities in mild cognitive impairment are associated with increased white matter network connectivity. Eur Radiol. 2018 Jan; 28(1):340-347. PMID: 28695358.
- Published on 7/5/2017
Drew DA, Koo BB, Bhadelia R, Weiner DE, Duncan S, la Garza MM, Gupta A, Tighiouart H, Scott T, Sarnak MJ. White matter damage in maintenance hemodialysis patients: a diffusion tensor imaging study. BMC Nephrol. 2017 Jul 05; 18(1):213. PMID: 28676035.
- Published on 6/21/2017
Bauer CM, Zajac LE, Koo BB, Killiany RJ, Merabet LB. Age-related changes in structural connectivity are improved using subject-specific thresholding. J Neurosci Methods. 2017 Aug 15; 288:45-56. PMID: 28647426.
- Published on 4/6/2017
Zajac L, Koo BB, Bauer CM, Killiany R, Behalf Of The Alzheimer's Disease Neuroimaging Initiative. Seed Location Impacts Whole-Brain Structural Network Comparisons between Healthy Elderly and Individuals with Alzheimer's Disease. Brain Sci. 2017 Apr 06; 7(4). PMID: 28383490.
- Published on 3/22/2017
Bauer CM, Hirsch GV, Zajac L, Koo BB, Collignon O, Merabet LB. Multimodal MR-imaging reveals large-scale structural and functional connectivity changes in profound early blindness. PLoS One. 2017; 12(3):e0173064. PMID: 28328939.
- Published on 1/1/2017
Corinna M. Bauer, Lauren E. Zajac, Bang-Bon Koo, Ronald J. Killiany, Lotfi B. Merabet. Age-related changes in structural connectivity are improved using subject-specific thresholding. Journal of Neuroscience Methods. 2017; 288:45-56.
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