Pathology & Laboratory Medicine News Items – Fall 2019
- New Faculty Member Dr. Sara Higgins
- We have a new joint NEIDL/Ex+ histotechnologist, Hans Gertje. Dr. Nick Crossland says they are thrilled to have him on board as our histology supervisor as we begin our BSL4 animal experiments at the NEIDL Hans is a graduate of Washington State University with a B.S. in Genetics and Cell Biology. He is an ASCP certified Histotechnologist with five years of industry experience in clinical and research laboratories, with focus on developing companion diagnostic marker assays and multiplex IHC panels. Hans lives in Saugus, MA with his wife and dog, and is expecting a daughter in October. In his free time he enjoys hiking with his family and watching football
- Dr Ivana Delalle will be leaving and joining the Alpert Medical School of Brown University faculty of Pathology and Laboratory Medicine on November 1, 2019 as the Director of Neuropathology at Brown and Lifespan Academic Medical Center, The Miriam and Rhode Island Hospitals. Dr Delalle was a highly valued member of our department and the BMC and BUSM community at large for 15 years. She will remain as adjunct faculty in the department.
- Dr Mostafa Belghasem will be leaving to serve as an Assistant Professor and biomedical science educator and pathology content expert at the Kaiser Permanente School of Medicine in Pasadena CA. Dr Belghasem has been a wonderful, innovative educator, scientist and administrator for our department, he will remain as an adjunct faculty member with us.
We all wish both colleagues good luck and success with their new opportunities
Nancy S. Miller, MD was an invited speaker at two State venues:
- 1) The Massachusetts State Public Health Laboratory, Bureau of Infectious Disease and Laboratory Sciences (9/5; The impact of the opioid crisis on the clinical microbiology laboratory)
- 2) The Office of the Chief Medical Examiner (9/11; Postmortem/Forensic Microbiology Update)
Dr. Dennis Jones has been named the Ralph Edwards Career Development Professor: http://www.bu.edu/provost/2019/09/17/2019-2020-career-development-professorship-awardees/\
Dr. Nicholas Crossland was awarded an NIH Shared Instrument Grant S10D026983-01 entitled “Ventana Discovery Ultra Research Auostainer”. This equipment will be managed by the Ex+ laboratory and offered as a core service. This machine performs an array of highly multiplexed tissue and cell based assays including both chromogenic and fluorescent immunohistochemistry and in situ hybridization. The success of this proposal reflects a multi-departmental collaboration that includes the following research laboratories in no particular order: Drs. Blusztajn, Chitalia, Remick, Senoo, Sahin-Toth, Jones, Wolozin, Rock, Colpitts, Ikezu, Kramnik, Duprex, Kurosawas, Haydar, Davey, Griffiths, and Mühlberger
Teresa Russell and Elysia Heiling, Masters Students working with Dr. Mostafa Belghasem, both have been selected to participate in the Kidney STARS 2019 trainees program organized by the American Society of Nephrology (ASN). Tersa and Elysia also received a travel grant from ASN to attend Kidney Week 2019
Dr. Ivana Delalle was invited to present a keynote lecture in the Presidential Symposium of the Croatian Neuroscience Meeting, September 12-15, Zadar, Croatia: Her lecture was entitled: “GWAS-identified Alzheimer’s disease risk variants – lessons from neuropathology”
Pathology Resident, Dr. Shoreh Fazeli presented a poster at 31st European Congress of Pathology held in Nice, France on September 11th. Title and authors: “May lesion size impact recognition of biologically aggressive noninvasive follicular thyroid neoplasm with papillary-like nuclear features? Meta-analysis”. Israa Laklouk, Shoreh R Fazeli, Reyhan Gedik, Sandra Cerda
Dr. Shoreh Fazeli at the 31st European Congress of Pathology held in Nice, France
Morgan Thompson, MS gave a poster presentation this past weekend: “Consenting Challenges toward Age, Ethnicity, and Co-Morbidity Matching of Cancer Patient and Control Populations at a Diverse Safety Net Hospital”. American Association for Cancer Research (AACR) Conference for Health Disparities, San Francisco, CA; Sept 20, 2019
Morgan Thompson, MS, at the American Association for Cancer Research (AACR) Conference for Health Disparities, San Francisco, CA
David Sherr, PhD gave a plenary talk at the International Dioxin 2019 meeting in Kyoto, Japan.
Dr. Sherr also recently received an R01 entitled “AHR-mediated immunosuppression in glioblastoma”
- Jain G, Stündl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A: A combined miRNA-piRNA signature to detect Alzheimer’s disease. (Accepted for publication in Translational Psychiatry)
- Canter RG, Choi H, Huang W-C, Wang J, Watson LA, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennet DA, Delalle I*, Chung K*, Tsai L-H* (*corresponding authors): 3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility. (Accepted for publication in Communications Biology)
Pathology & Laboratory Medicine News Items –
Special New News Edition: September 2019
Pathology & Laboratory Medicine News Items – July 2019
Recent Faculty Promotions:
- Mostafa Belghasem, PhD, MA; Assistant Professor of Pathology & Laboratory Medicine
- New Faculty Member Dr. Jonathan Cherry
- New Cytopathology Fellow Dr. Osman Yilmaz
Dr. Mostafa Belghasem has joined the Disease & Therapy (DRx) Curriculum Leadership Team and will serve as the department representative effective April 2109
Dennis Jones, PhD, Assistant Professor of Pathology & Laboratory Medicine, has been awarded the Dahod Assistant Professorship for 2019-2020
Dr. Jones was also featured on the GMS website. http://www.bumc.bu.edu/gms/meet-dennis/
PiBS student Guillermo Arroyo-Ataz has joined the Dennis Jones Lab for his thesis research. Guillermo graduated with an undergraduate degree in biotechnology from the Universidad Francisco de Vitoria. He has two Master's of Science degrees- one in Genes, Drugs and Stem Cells from Imperial College London and the other in Biophysics from the Universidad Autónoma de Madrid.
PiBS Student Thomas Bellio has joined the Lee Goldstein Lab. Thomas graduated from Stonehill College in May 2018 with a B.S. in Neuroscience. He loves to play tennis and am a diehard Toronto Maple Leafs fan. In the Goldstein Lab he is studying the biomechanical underpinnings of concussion and traumatic brain injury in the lab and has received the BU NSF NRT Neurophotonics Fellowship
MD/PhD Student Daniel Kirsch has joined the Ann McKee Lab. He got his BA in biochemistry from The City University of New York-Baruch and is currently in BU's MD/PhD program. In his free time, Daniel enjoys reading, museums, and traveling. Currently, he teaches the gross anatomy lab for Sargent College. Daniel is originally from the Bay Area
- Chandler KB, Leon DR, Kuang J, Meyer RD, Rahimi N, Costello CE. N-glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2). Journal of Biological Chemistry. 2019, In Press
- Rachel Xi-Yeen Ho, Rawan Tahboub, Razie Amraei, Rosana D. Meyer, Nitinun Varongchayakul, Mark Grinstaff, Nader Rahimi. The cell adhesion molecule IGPR-1 is activated by, and regulates responses of endothelial cells to shear stress. Journal of Biological Chemistry, In press, 7/2019
- Shruti Kannan, Laura A. Morgan, Benjamin Liang, McKenzie G. Cheung, Christopher Q. Lin, Dan Mun, Ralph G. Nader, Mostafa E. Belghasem, Joel M. Henderson, Jean M. Francis, Vipul C. Chitalia, Vijaya B. Kolachalama. Segmentation of Glomeruli Within Trichrome Images Using Deep Learning. Kidney International Reports. Published April 15th 2019
- Mostafa Belghasem, Ousama A’amar, Daniel Roth, Joshua Walker, Nkiruka Arinze, Sean Richards, Jean Francis, David Salant, Vipul Chitalia, Irving J Bigio. Towards minimally-invasive, quantitative assessment of chronic kidney disease using optical spectroscopy. Nature Scientific Reports. Published May 9th 2019
- Chimera Lyle, Mostafa Belghasem, Vipul C. Chitalia. c-Cbl: An Important Regulator And A Target In Angiogenesis And Tumorigenesis. Cells. Published May 12th 2019
- Wang Y, Liu CH, Ji T, Mehta M, Wang W, Marino E, Chen J, Kohane DS ; Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles.. Nat Commun. 2019 Feb 18;10(1):804. doi: 10.1038/s41467-019-08690-4. PMID: 30778060
- Zhao C, Liu A, Santamaria CM, Shomorony A, Ji T, Wei T, Gordon A, Elofsson H, Mehta M, Yang R, Kohane DS. Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity. Nat Commun. 2019 Jun 12;10(1):2566. doi: 10.1038/s41467-019-10296-9.PMID: 31189915: This was featured on FOX25 news: Boston Children's researchers believe toxic fish could help solve ...https://www.boston25news.com/news/boston-children-s...believe.../958018795 And Boston Children’s Hospital front page news:http://discoveries.childrenshospital.org/tetrodotoxin-pain/
Pathology & Laboratory Medicine News Items – May-June 2019
- New Faculty Member Dr. Zhichun Lu
- New Resident Dr. Kina Ma
- New Resident Dr. Charitha Vadiamudi
- New PhD Students: Guillermo Arroyo and Thomas Bellio, as well as MD/PhD Student Daniel Kirsch
Recent Faculty Promotions:
- Tiffany Mellott, PhD has been appointed to GMS Faculty
- Dr. Sandra Cerda was an invited guest speaker at the Pathology Grand Rounds in Weill Cornell Medicine Pathology Department, New York. My presentation on May 6 was titled; “Predictive value of thyroid malignancy using ThyroSeq V.2 Multigene Next Generation Sequencing Panel Analysis in Thyroid FNAs with Indeterminate Cytology Diagnosis.”
- New Pathology PiBS student Thomas Bellio and MD/PhD student Kelley Andersen had a poster presentation at the American Association of Neuropathologists meeting on June 7 in Atlanta, GA, entitled: ““Activin Receptor-Like Kinase 1 Expression in Hippocampal Arterioles Decreases in Alzheimer’s Disease and Amyloid Angiopathy” Kelley E.T. Anderson*, Thomas A. Bellio*, Stephanie L. Adams, Emily Aniskovich, Jan K. Blusztajn, and Ivana Delalle
- Both Dr. Nitin Marwaha and Dr. Yachana Kataria have been selected for admission into the Faculty Early Career Development Program
- Second Year Masters Student, Amanda Araujo’s abstract was accepted and she will be presenting in October at Society for Neuroscience!! Her abstract title is: “Visualization and Assessment of Stellate Ganglia Neuronal Remodeling in Association with Myocardial Infarction and Coronary Artery Disease”
- Dr. Anna Belkina was invited to present as a plenary speaker at the annual Canadian Cytometry and Microscopy Association meeting (CCMA 2019 Cytometry & Microscopy Symposium). She presented a talk entitled " Revealing Disease Phenotypes with Computational Analysis of High-Dimensional Flow Cytometry Data" on June 18, 2019. She also conducted a two-hour bootcamp workshop for the symposium attendees entitled: "Right tools for the job, right job for the tools: computational analysis methods for cytometry data"
- Dr. Belkina was also invited by the organizers of the annual ISAC (International Society for the Advancement of Cytometry) international conference to conduct a scientific tutorial at CYTO 2019 conference. The tutorial was presented on June 22, 2019 and entitled: "Best t-SNE on the block: how to achieve a meaningful low-dimensional embedding and interpret it correctly"
- She was asked by the organizers of the annual ISAC (International Society for the Advancement of Cytometry) international conference to present her at at CYTO 2019 conference. Her oral presentation on June 26, 2019 was entitled: "Ditch the ball: automated optimized parameters for t-distributed stochastic neighbor embedding improve visualization and allow analysis of large datasets"
- Also Dr. Belkina's trainee, Riley Pihl, MS has reported the lab's most recent results at the same meeting in an oral presentation entitled: "Multivariate analyses of high parameter spectral flow cytometry and plasma analyte datasets reveal links between gamma delta T cell subsets and plasma markers of systemic inflammation and/or gut permeability with ART-suppressed HIV infection and healthy aging". This is Riley's first oral presentation at a major conference!
- Nitin Marwaha, MD, FASCP has completed the University of Pathology Informatics course of training conducted in joint consideration with ASCP/API
- Dr. Eric Burks has an abstract accepted for an oral presentation at 2019 World Conference on Lung Cancer in Barcelona Spain, September 9, 2019; “Stage I Lung Adenocarcinoma Gene Expression Associated with Aggressive Histologic Features for Guiding Precision Surgery and Therapy”
- Dr. David Sherr recently received 2 new grants, an R21 (1 percentile) and an R01 (2 percentile), on the role of the aryl hydrocarbon receptor as an immune checkpoint in oral and brain cancer respectively.
- Dr. Sherr will also be giving a keynote lecture at this week’s Immuno-oncology Pharma Congress in Boston titled “The AHR in Cancer Immuno-metabolism”
- This Year’s Graduation Dinner was held on Tuesday, June 18th at the newly renovated BU Castle:
- Graduating Resident, Dr. Shoreh Fazeli was awarded the coveted Robert Foley Award at this year’s Graduation Dinner
- PUBLICATIONS: Accepted
- John Kim, Leen Arnout, Daniel Remick; “Hydrocortisone, Ascorbic Acid and Thiamine (HAT) Therapy Decreases Oxidative Stress, Improves Cardiovascular Function and Improves Survival In Murine Sepsis” Shock
- P. Calner, H. Foss, G. Ruiz-Mercado; N. Miller, C. Andry, L. Battisti, K. Scrudder; F. Shea, A. Chan, E. Schechter-Perkins. HCV Screening, Linkage to Care, and Treatment Patterns at Different Sites Across One Academic Medical Center: Accepted for publication in PLOS ONE
- Yachana Kataria, Israa Laklouk; “Utility of Glucose Levels in Penial Blood Sample to Assess Recurrent Priapism” Journal of Clinical Chemistry
- PUBLICATIONS: Published
- Ross AE, Bengani LC, Tulsan R, Maidana DE, Salvador-Culla B, Kobashi H, Kolovou PE, Zhai H, Taghizadeh K, Kuang L, Mehta M, Vavvas D, Kohane DS, Ciolino JB: Topical sustained drug delivery to the retina with a drug-eluting contact lens. Biomaterials 2019; (in press)
- Chao Zhao, Andong Liu, Claudia M. Santamaria, Andre Shomorony, Tianjiao Ji, Tuo Wei, Akiva Gordon, Hannes Elofsson, Manisha Mehta, Rong Yang, Daniel S. Kohane; “Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity.” Nature communications. 12 June 2019
- RamkripaRaghavana Blandine BustamanteHelfrichb Sandra R.Cerdac YuelongJiaIrinaBurdd GuoyingWanga XiumeiHonga LinglingFue ColleenPearsone M.Daniele Fallinf BarryZuckermane XiaobinWangag: “Preterm birth subtypes, placental pathology findings, and risk of neurodevelopmental disabilities during childhood.” Placenta. Now available online: panelRamkripaRaghavanaBlandine BustamanteHelfrichbSandra R.CerdacYuelongJiaIrinaBurddGuoyingWangaXiumeiHongaLinglingFueColleenPearsoneM.Daniele FallinfBarryZuckermaneXiaobinWangag
Recent Faculty Promotions:
- Sandra Cerda, MD, Associate Professor of Pathology & Laboratory Medicine
- Hui Chen, MD, Assistant Professor of Pathology & Laboratory Medicine
On behalf of Dr. Joel Henderson, Residency Program Director: "I am pleased to announce that the ACGME Review Committee for Pathology has decided to continue our status as a fully-accredited pathology residency program, without condition"
At the recent Medical Student Awards Ceremony held on Friday, March 15th is Keefer Auditorium:
- PATHOLOGY AWARDS: Presented by Dr. Joel Henderson:
- The Geoffrey Boughton Award is presented to an outstanding student in Pathology in honor of Dr. Boughton, BUSM class of 1954. Please join me in congratulating: Nisma Mujahid, MD/PhD
- The Leonard and Julius Gottlieb Prize in Pathology Education is awarded to a member of the graduating class who has excelled in pathology. This award was established in 2008 by Mrs. Dorothy Gottlieb in honor of her late husband, Leonard, and his father, Julius. Congratulations to this year’s recipient: Gabriel Lerner
Congratulations to this year’s Graduates!!!
- Dr. Reyhan Gedik, will be moving on to University of California, San Francisco, General Surgical Pathology
- Dr. Israa Laklouk; will enter a fellowship at Massachusetts General Hospital, Head & Neck Pathology
- Dr. Mahmoud Soliman; is going to Beth Israel Deaconess Medical Center, Hematopathology
- Dr. Jing Yang: Jing will be moving on to a surgical pathology fellowship at Brigham and Women's Hospital
- Razie Amraei, MS: Razie will be joining BU’s PiBS/PhD Program in the Fall
- Ekow Ambaah, MS; is seeking a position in industry
- Ellie Bruns, MS: will be staying on with Dr. Blusztajn continuing work on her project
- Nicole Derosia; MS; Nicole is also looking for a situation in industry
- Dr. Yuri Kim, PhD: will be attending medical school after graduation at the American University of the Caribbean, (she is also wait-listed at a DO school
- Sarah Langlois, MS; is also seeking a position in industry
- Dr. Timothy Norman, PhD: is doing a postdoc in the laboratory of Jason Rock, PhD in the Center for Regenerative Medicine focused on bioengineering strategies for lung regeneration
- Joseph Tashjian, MS: has accepted a position with Dr. Joel Henderson’s Lab
- Michelle Wei, MS: will be tacking a tech position in Dr. Remick’s Lab
April 21-27 was Medical Laboratory Professional’s Week 2019. To celebrate and honor our Lab Professionals there were many fun, educational & interesting activities, including:
- Wear Jeans to Benefit the BMC Food Pantry
- Pac-Man Game
- Pipetting Competition
- Continuing Education Webinars
- MLS Student Case Presentations (w/ Continental Breakfast & Refreshments)
- Bake Off Competition
- Lab Photo Booth
- Afternoon Tea
- Pizza Day
- Roche Presentation on HIV
- Team ‘Building’ Activities
- Ice Cream Social
- Donning and Doffing Competition (VHF)
- Bravo to all of our Medical Laboratory Professions for their jobs well done!!
Dr. Remick also organized a symposium at the 2019 Experimental Biology Meeting, Sepsis: Clinical Issues and Research Initiatives
In addition Dr. Remick presented an invited presentation at the 2019 Experimental Biology meeting, Giving and Responding to Criticism of Your Grant. The session was organized by the Diversity and Development Committee of the American Society of Investigative Pathology and was co-sponsored by the American Association of Anatomists
Dr. Carmen Sarita-Reyes has have been appointed to serve as a member of the United States Medical Licensing Examination (USMLE) Pathology and Genetics Test Material Development Committee (TMDC) effective March 2019
New PhD Graduate, Dr. Timothy Norman, was voted to give this year’s PhD Commencement speech!!
- Accepted for publication (4/15/2019) in Clinical Microbiology Reviews, Nancy S. Miller, M.D. contributing author: "A Laboratory Medicine Best Practices Systematic Review and Meta-Analysis of nucleic acid amplification tests (NAAT) and algorithms including NAAT for the diagnosis of Clostridioides (Clostridium) difficile in adults". Paper #CMR00032-18R2. C. Kraft and 23 contributing authors
- Shomorony A, Santamaria CM, Zhao C, Rwei AY, Mehta M, Zurakowski D, Kohane DS: Prolonged duration local anesthesia by combined delivery of capsaicin- and tetrodotoxin-loaded liposomes. Anesth Analg, March 2019; (in press)
- A computational solution to improve biomarker reproducibility during long-term projects Feng Feng , Morgan P. Thompson, Beena E. Thomas, Elizabeth R. Duffy, Jiyoun Kim, Shinichiro Kurosawa, Joseph Y. Tashjian, Yibing Wei, Chris Andry, D. J. Stearns-Kurosawa; PLoS One, April 17, 2019. https://doi.org/10.1371/journal.pone.0209060
- Wong CK., Gromisch C., Ozturk S., Papageorgis P., Abdolmaleky HM., Reinhard BM., Thiagalingam A., and Thiagalingam S. 2019. MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer Cancer Biology & Therapy 2019 Mar 28:1-8. doi: 10.1080/15384047.2019.1595285 [Epub ahead of print]
- Abdolmaleky HM, Gower A, Wong CK, Cox JW, Thiagalingam A, Zhang X, Shafa R, Sivaraman V, Zhou J-R, and Thiagalingam S. 2019. Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain asymmetry in schizophrenia and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2019 Mar;180(2):138-149. doi: 10.1002/ajmg.b.32691. Epub 2018 Nov 23
- Kalli M, Mpekris F, Wong CK, Panagi M, Ozturk S, Thiagalingam S, Stylianopoulos T, and Papageorgis P. 2019. Activin A signaling regulates IL13Rα2 expression to promote breast cancer metastasis. Front. Oncol. 9:32. 2019 Feb 5; doi: 10.3389/fonc.2019.00032
Pathology & Laboratory Medicine News Items – March 2019
Recent Faculty Appointments:
Congratulations to Dr. Dennis Jones on your appointment to GMS Faculty
Congratulations to Ms. Liz Duffy on your appointment to GMS Faculty
Dr. Dennis Jones received a 2019 George K. Michalopoulos Junior Faculty Travel Award. This award is funded by the George K. Michalopoulos Award Fund and will be presented at the American Society for Investigative Pathology 2019 Annual Meeting at the Experimental Biology conference
Dr. Jones will also be giving an oral presentation titled “Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction” at the Experimental Biology conference in April
Dr. Ivana Delalle attended the international conference, AD/PD (Alzheimers’s Disease / Parkinson’s Disease) meeting in Lisbon, Portugal, March 26-31,presenting the results of the study “Methionine Sulfoxide Reductase-B3 risk allele implicated in Alzheimer’s disease associates with increased odds for brain infarcts” we published last month in Journal of Alzheimer’s disease (PMID: 30775993)
Cheryl Spencer was a participant in the 1ST ANNUAL BMC NEWBORN AND PEDIATRIC BEREAVEMENT CONFERENCE and gave an introductory presentation "Reporting fetal death to Decedent Affairs office and office of the Chief of Medical Examiner, fetal disposition by family and hospital, and autopsy permission and points of contact". This conference took place in the Moakley Simulation Center. The Audience was nurses from Labor and Delivery, NICU, pedi-ED, Pediatrics, and OR.
Three of our residents, Israa Laklouk, Artem Shevtsov and Ilyas Yambayev participated in the USCAP 2019 the week of March 18th:
- Israa Laklouk, MD gave a Poster presentation: “Race-ethnicity Associated Disparities of Molecular Genotyping in Classical Papillary Thyroid Carcinoma, Follicular Variant Papillary Thyroid Carcinoma, and Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP): an Institutional Experience, 162 Patients” Authors: Israa Laklouk, Reyhan Gedik, Sandra Cerda
Dr Sandra Cerda was invited as the guest Grand Rounds lecturer at the Department of Pathology in Montefiore, March 7th. Her talk was on “Multigene Next Generation Sequencing Panel Analysis and its application on Cancer Diagnosis in FNA of Thyroid Nodules with Indeterminate Cytology”
From Dr. Nader Rahimi’s Lab: Congratulations to Razie Amraei, a current Pathology Master student and Rachel Ho, a former MAMS student working in Nader Rahimi's laboratory, who have been accepted into Boston University PIBS PhD program
Nancy S. Miller, M.D accepted an invitation to serve on the Ignition Award Review Committee for the Office of Technology Development, Boston University
- Dr. Miller also accepted a 2-year term as a Committee Member for the American Society for Microbiology Distinguished Lecturer Program
- In addition Dr. Miller is invited faculty and presenter at the workshop “Epidemics Within the Opioid Epidemic: The Infectious Disease Consequences” presented at the 4th Joint Meeting of the Northeast Association for Clinical Microbiology and Infectious Disease and Northeast-Branch-American Society for Microbiology with the New Hampshire Department of Health and Human Services and the Massachusetts Department of Public Health, April 8, Portsmouth, NH. Dr. Miller will present “Diagnostic Microbiology in the Ongoing Opioid Epidemic: A case-based approach.”
Yuri Kim, PhD (Lee Quinton’s Lab) successfully defended her Thesis, “Liver-Dependent Protection During Pneumonia and Sepsis” on Thursday, March 28th; Bravo Yuri!!
Pathology & Laboratory Medicine News Items – Winter 2018/2019
Recent Faculty Promotions
Elizabeth Duffy, MA; Assistant Professor of Pathology & Laboratory Medicine
Carolina Lyon de Ana, a former Pathology Masters student in the lab of Dr. Susan Winandy, published her Masters research as part of a first author publication in The Journal of Immunology! Other authors include Ksenia Arakcheeva, Nicole Derosia (a current Pathology Masters student) and Dr. Parul Agnihotri (a former PhD student). Congratulations to all! Check it out online: Lack of Ikaros deregulates inflammatory gene programs in T cells by Carolina Lyon de Ana, Ksenia Arakcheeva, Parul Agnihotri, Nicole Derosia and Susan Winandy. The Journal of Immunology. 202: 1112-1123. The article was chosen as the Editor-In-Chief's pick of the issue and will be featured in the "In This Issue" section, which highlights articles considered to be among the top 10% of articles published The Journal. BRAVO Carolina!!!
Dr. Ivana Delalle was invited as one of 9 international speakers at the symposium held in Boston on Nov 28, 2018 “Longwood extracellular vesicle symposium: from science to therapeutics”
Nancy S. Miller, M.D. was an invited speaker at the TriMark Point of Care/Critical Care Conference, October 12, 2017 in Dedham, MA. Dr. Miller will present: "What's the Point? A Point of View About Point of Care and Diagnostic Microbiology Testing in the U.S.”
Dr. Miller also presented “A point of view about point of care testing for diagnostic microbiology in the U.S.” at the Global Applied Microbiology Conference, October 18-19, Toronto, Ontario, Canada
Dr. Miller was an ASM Distinguished Lecturer at the Southern California Branch-American Society for Microbiology, October 27-28, La Jolla, CA. Also at La Jolla, Dr. Miller was invited to a breakout Educators’ Session and presented, “Clinical Microbiology at the Crossroads: A Potpourri of Challenges and Lessons Learned in this Era of Evolving Technology”
Troy Sanders, a MAMS student in the lab of Dr. Susan Winandy, has been accepted into medical school at UCLA. He has also been awarded the prestigious Geffen Scholarship, which will pay for his tuition and room/board. Congratulations Troy!
Dr. Israa Laklouk won the first place resident research award at the USCAP meeting in Vancouver, for her first author abstract: Impact of racial and ethnic differences on the accurate classification of thyroid nodules using ThyroSeq Next-Generation Sequencing. Coauthors are Cecilia Ponchiardi, David Kindelberger, and Sandra Cerda
In Mid-October one of our new Masters Students, Amanda Araujo, attended and presented at the Northeastern Association of Forensic Sciences (NEAFS) conference in Bolton landing, NY. She presented her undergraduate research in forensic biology/DNA titled “Following the Transfer of Touch DNA in Simulated Carjackings”
Nancy S. Miller, M.D. presented an all-day Medical Mycology Workshop at The John A. Burns School of Medicine, University of Hawai’i at Manoa, February 11, Oahu, Hawai’i.
For Dr. Anna Belkina; https://www.frontiersin.org/articles/10.3389/fimmu.2018.02783/full It’s a # 1 paper in Viral Immunology section (per reads) over last 6 months despite it being online for less than 3 months. She will be talking about this work at a webinar organized by Cytobank on March 20.
Dr. Belkina was also invited to talk at FlowTex 2019 conference at MD Anderson Cancer Center Feb 6-7 as a plenary speaker and have presented a talk entitled “Revealing Disease Phenotypes with Computational Analysis of High-Dimensional Flow Cytometry Data”.
Dr. Dennis Jones was selected to receive pilot funding from the American Cancer Society Pilot Program at the Boston University-Boston Medical Center Cancer Center
Dr. Jones also received a Minority and Minority-Serving Institution Faculty Scholar in Cancer Research Award from the American Association for Cancer Research
Nancy S. Miller, M.D. also presented “Clinical Microbiology Update” at Grand Rounds for the Division of Infectious Diseases, December 13th
Dr. Shinichiro Kurosawa has had his service as a member of the Boston University Laboratory Safety Committee extended through 12/31/2020
Liz Duffy, MA has been appointed as a voting member of the Boston University Laboratory Safety Committee effective immediately. The term of her appointment is through 12/31/2021
Dr. Kazem Azadzoi has received a VA Merit Review grant award for his research proposal entitled "Regulation of Detrusor Overactivity by Cellular Stress in Bladder Ischemia"
Timothy Norman, PhD (Alan Fine Lab) successfully defended his Thesis, “Ontogeny and maturation of the lymphatic endothelium in the lung” on Tuesday, February 26th; Bravo Tim!!
Conner SC, Benayoun L, Himali JJ, Adams SL, Yang Q, DeCarli C, Beiser A, Seshadri S, and Delalle I: Methionine Sulfoxide Reductase-B3 risk allele implicated in Alzheimer’s disease associates with increased odds for brain infarcts. Journal of Alzheimer’s Disease
Shoreh R. Fazeli,Kamyar R. Giglou ,Mahmoud Soliman, Waleed H. Ezzat, Andrew Salama, Qing Zhao. Calcifying Epithelial Odontogenic (Pindborg) Tumor in a Child: A Case Report and Literature Review. Head and Neck Pathology Journal
Reggie Thomasson, MS, MD; International Assessment of Massive Transfusion Protocol Contents and Indications for Activation" was accepted for publication in the journal TRANSFUSION
Wang Y, Liu C-H, Ji T, Mehta M, Wang W, Marino E, Chen J, Kohane DS: Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles. Nat Commun 2019; (in press)
Yang R, Saarinen R, Okonkwo OS, Hao Y,Mehta M, Kohane DS: Trans-tympanic delivery of local anesthetics for pain in acute otitis media. Mol Pharm 2019; (in press)
Anna C. Belkina1,2, Alina Starchenko3, Katherine A. Drake4, Elizabeth A. Proctor3, Riley M. F. Pihl1, Alex Olson5, Douglas A. Lauffenburger3, Nina Lin5† and Jennifer E. Snyder-Capp: Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging. Frontiers of Immunology, 05 December 2018 PRESS RELEASE:https://www.sciencedaily.com/releases/2018/12/181211112944.htm
Latarsha J. Carithers, Rachana Agarwal, Ping Guan, Hana Odeh, Michael C. Sachs, Kelly B. Engel, Sarah R. Greytak, Mary Barcus, Conrado Soria, Chih-Jian (Jason) Lih, P. Mickey Williams, Philip A. Branton, Leslie Sobin, Benjamin Fombonne, Therese Bocklage, Chris Andry,Elizabeth R. Duffy, Gabriel Sica, Rajiv Dhir, Scott Jewell, Nancy Roche, and Helen M. Moore; The Biospecimen Preanalytical Variables Program: A Multiassay Comparison of Effects of Delay to Fixation and Fixation Duration on Nucleic Acid Quality. Archives of Pathology & Laboratory Medicine, Early Online Release
Pathology & Laboratory Medicine News Items – Fall 2018
Recent Faculty Promotions:
- Chris Andry, MPhil, PhD, Professor of Pathology & Laboratory Medicine and Family Medicine
- Lawreen Connors, PhD, Professor of Pathology & Laboratory Medicine
- Rob Pistey, MD, Clinical Associate Professor of Pathology & Laboratory Medicine
Dr. Eric Burks was an Invited Speaker at the 39th International Conference on Screening for Lung Cancer (I-ELCAP)/7th Conference on Research for Early Lung Cancer Treatment (I-ELCART) in Hyde Park NY. - October 16-17, 2018. He presented the following lecture: "Aggressiveness of Stage I Lung Cancer. Size, grade, histology: what do we know?”
- Dr. Burks also gave a Poster Presentation at IASLC 19th World Conference on Lung Cancer 2018, Toronto, Canada, on September 24, 2018. Burks E.J., Sands J.M., Sullivan T., Regis S.M., McKee B.J., McKee A.B., Rieger-Christ K.M. Pathologic Comparison of Prevalent vs. Incident CT Lung Screen Detected Cancer in NCCN High-Risk Subjects: Are The Different?
- Dr. Burks received 20% salary support from the Spira-Lenburg Lab to work with their group on the Pulmonary Precancer Genome Atlas (PCGA) defining the molecular and pathologic changes in a multi-institutional cohort of smokers undergoing sequential autoflorescence bonchoscopic biopsies
Dr. Dennis Jones was recently recognized recently by STAT newspaper. https://www.statnews.com/wunderkinds/
USCAP 2019; United States & Canadian Academy of Pathology’s 108th Annual Meeting in National Harbor, Maryland, March 16-21, 2019
- “Inflammatory Patterns by H&E Stain are Predictive of Recurrence in Resected Stage I Lung Adenocarcinoma.”, abstract number #2175, United States & Canadian Academy of Pathology’s 108th Annual Meeting for presentation in the Stowell-Orbison/Surgical Pathology/Autopsy Award Poster Session. Authors: I Yambayev, A Shevstov, P Moreira, T Sullivan, K Rieger-Christ, K Suzuki, E Burks
- “Distinctive Pulmonary Amyloid Vasculopathy is the Most Common Lung Finding at Autopsy in Patients with AL Amyloidosis.”, abstract number #2148, United States & Canadian Academy of Pathology’s 108th Annual Meeting for presentation in the Stowell-Orbison/Surgical Pathology/Autopsy Award Poster Session. Autors: M Soliman, R Multz (med student), L Connors, H Cui, A Staron, V Sanchorawala, E Burks
- Race-ethnicity Associated Disparities of Molecular Genotyping in Classical Papillary Thyroid Carcinoma, Follicular Variant Papillary Thyroid Carcinoma, and Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP): an Institutional Experience, 162 Patients. Israa Laklouk MD, Reyhan Gedik MD, Sandra Cerda MD
New course offered in the School of Graduate Medical Sciences. Our department will be offering a graduate level histopathology course (PA932) created by Dr. Mostafa Belghasem starting the summer of 2019. The course proposal was very well received by the University’s Academic Policy Committee and no scheduled hearing was required. This new course will fill an unmet need within the graduate school to teach the practical and fundamental skills required of tissue processing, tissue staining, and interpretation of pathologic changes in tissues and organs. The course features several board-certified pathology instructors and the small class size ensures that all students are provided with adequate hands-on time.
Dr. Belghasem also presented an oral abstract during Evans Research Day 2018 titled “Newly Identified Metabolites Connect Colon Cancer to Thrombosis” Mostafa Belghasem, Sean Richards, Joshua Walker, Cristal Thompson, Cheryl Spencer, Chris Andry, Katya Ravid, Vipul Chitalia.
Daniel Remick, M.D., participated on a panel discussion at the PISA 2018 meeting in Ann Arbor Michigan “Maximizing Biospecimen Resources” October 2018
Daniel Remick, M.D., was invited to give the plenary lecture at the Department of Pathology’s Research Day at the University of Iowa on October, 23, 2018. His talk was “Mechanisms of Traumatic Brain Injury Augmenting Innate Immunity”
Max Vaickus, former Masters student in the Department had his paper accepted in the American Journal of Pathology: “Mild traumatic brain injury in mice beneficially alters lung NK1R and structural protein expression to enhance survival after Pseudomonas aeruginosa infection. Max Vaickus, Terry Hsieh, Ekaterina Kintsurashvili, Jiyoun Kim, Daniel Kirsch, George Kasotakis, Daniel Remick
Dr. Anna Belkina was a plenary speaker at the MetroFlow 2018 meeting in New York, NY with a talk entitled: “From Chaos to Chorus: Revealing disease phenotypes with computational analysis of high-dimensional flow cytometry” October 18, 2018
Resident, Dr. Mahmoud Soliman presented his poster the American Society for Clinical Pathologists October 3-5 in Baltimore. "A report of a case of hyalinizing trabecular neoplasm of thyroid gland associated with PAX8-GLIS3 fusion" Authors: Mahmoud Soliman, Artem Shevtsov, Grace Zhao and Sandra Cerda
Resident, Dr. Shoreh Fazeli presented a poster at the Massachusetts Medical Society on Friday, November 30.: “Impact of ThyroSeq v2 Testing on Cytopathology diagnosis, Cost, and Outcome of Management in Patients with Thyroid Nodule” S R. Fazele, B Zehn, D Kindelberger, S Lee, S Cerda
Dr. Chris Andry’s appointment as Co-Chair of the Boston University Laboratory Safety Committee has been renewed through December 2019
Dr. Deborah Stearns-Kurosawa just completed her term as Chair of the Institutional Biosafety Committee. “Her leadership as Committee Chair and her contributions to the program have helped to ensure research at BU has been conducted in a safe and compliant manner, consistent with the highest ethical standards
Our Residency Program Day-After-Thanksgiving International Pot Luck! Program Director, Dr. Joel Henderson had a great time and learned a lot about recipes from all over the world – These were enjoyed by all! Dr. Henderson and our residents appreciated having the opportunity to chat about things without the usual pressures of a typical workday
2018 Residency Program Day After Thanksgiving Thanksgiving
- Browne B.M., Sullivan T.B., Libertino J.A., Burks E.J., Canes D., Rieger-Christ K.M. MicroRNA expression profiles in upper tract urothelial carcinoma differentiate tumor grade, stage and survival: implications for clinical decision-making.” Manuscript accepted to Urology October 2, 2018
- "Lack of Ikaros deregulates inflammatory gene programs in T cells" by Carolina Lyon de Ana, Ksenia Arakcheeva, Parul Agnihotri, Nicole Derosia and Susan Winandy. Accepted by The Journal of Immunology
- Christopher Weldon, Tianjiao Ji, Minh-Thuy Nguyen, Alina Rwei, Weiping Wang, Yi Hao, Chao Zhao, Manisha Mehta, Bruce Y. Wang, Robert P. Marini, and Daniel S. Kohane: “Nanoscale Bupivacaine Formulations to Enhance the Duration and Safety of Intravenous Regional Anesthesia. ACS Nanao, Publication Date (Web): October 23, 2018
- Weiwei Shi, Ram Al-Sabti, Nelson Mantilla-Rey, and Karen Quillen. "Quality Management of massive transfusion protocol incorporating tranexamic acid adherence." Published in Transfusion and Apheresis Science
Pathology & Laboratory Medicine News Items – August/September 2018
Daniel Remick, MD was an invited speaker to the International Sepsis Symposium in Chicago, and participated on the Immunology panel. His talk was titled: Heterogeneity in the Septic Immune Response.
Nick Crossland, DVM, DACVP was an invited speaker on August 7th at Rocky Mountain Laboratories, which hosted a symposium on the Use of Laboratory Animals in Infectious Disease Research. The title of his talk was “The Use of Fluorescent Reporter Viruses to Investigate Measles Pathogenesis”
Resident, Israa Lakloud, MD presented the abstract entitled “Impact of Race/Ethnicity on Oncogenic Driver Mutations Prevalence and Outcomes in Thyroid Nodules” as an Oral Presentation as part of the Scientific Program during the 30th European Congress of Pathology in in Bilbao, Spain from 8 - 12 September 2018. The authors: Israa Laklouk MD., Cecilia Ponchiardi MD., Sandra Cerda MD
A series of manuscripts arising from the Wiggers-Bernard Conference in Vienna have been accepted. Dr. Remick was part of the organizing committee for the conference:
- MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTIPSS): AN INTERNATIONAL EXPERT CONSENSUS INITIATIVE FOR IMPROVEMENT OF ANIMAL MODELING IN SEPSIS. Osuchowski MF, Ayala A, Bahrami S, Bauer M, Boros M, Cavaillon JM, Chaudry IH, Coopersmith CM, Deutschman C, Drechsler S, Efron P, Frostell C, Fritsch G, Gozdzik W, Hellman J, Huber-Lang M, Inoue S, Knapp S, Kozlov AV, Libert C, Marshall JC, Moldawer LL, Radermacher P, Redl H, Remick DG, Singer M, Thiemermann C, Wang P, Wiersinga WJ, Xiao X, Zingarelli B.in press, 2018, Shock. PMID 3016875
- PART II: MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR TYPES OF INFECTIONS AND ORGAN DYSFUNCTION ENDPOINTS. Libert C, Ayala A, Bauer M, Cavaillon JM, Deutschman C, Frostell C, Knapp S, Kozlov AV, Wang P, Osuchowski MF, Remick DG. in press, 2018, Shock. PMID 3016873
- A peer-reviewed paper was published detailing the premise for standardized sepsis models.
- PREMISE FOR STANDARDIZED SEPSIS MODELS. Remick DG, Ayala A, Chaudry I, Coopersmith CM, Deutschman C, Hellman J, Moldawer L, Osuchowski M. in press, 2018, Shock. PMID: 29877959.
- The following manuscripts investigating sepsis have been accepted
- NEUROKININ-1 RECEPTOR DEFICIENCY IMPROVES SURVIVAL IN MURINE POLYMICROBIAL SEPSIS THROUGH MULTIPLE MECHANISMS IN AGED MICE. Juan R. Mella, Arthur F. Stucchi, Elizabeth R. Duffy, Daniel G. Remick in press 2018, Shock PMID 30095600
- MYOCARDIAL REDOX HORMESIS PROTECTS THE HEART OF FEMALE MICE IN SEPSIS. Luptak I, Croteau D, Valentine C, Qin F, Siwik D, Remick D, Colucci WS, Hobai I. in press, 2018, Shock PMID 30102640
One of our new faculty members, Dr. Reggie Thomasson will be presenting a poster at AABB in Boston on October 14th entitled "International Assessment of Massive Transfusion Protocol Types and Activation Indications"
Dr. Thomasson is also giving a talk at the Northeast Laboratory Conference on October 16th in Portland, Maine entitled "Pathogen Inactivation of Blood Components: Impact on Blood Banking and Transfusion Medicine"
Andrew Berens, Assistant Supervisor in Microbiology, recently obtained his MBA from Western Governors University and his specialist in Microbiology ASCP certification. BRAVO!
First Year Masters Student, Kyle de la Cena has graciously volunteered to serve as our program's liaison to Graduate Medical Sciences Student Organization (GMSSO) in GMS for the year
Resident, Weiwei Shi, MD recently accepted a surgpath fellowship offer for 2020-2021 at MSKCC, Memorial Sloan Kettering Cancer Center in New York City and one of the most prestigious cancer centers in the world
Leen Arnaout, a Boston University Undergraduate, is a sophomore in biomedical engineering. Leen, who is conducting research in Dr. Remick’s Lab, has received an UROP Student Research Award
- Schechter-Perkins EM, Mitchell PM, Nelson KP, Liu JH, Shannon A, Ahern J, Orr B, Miller NS. Point-of-care influenza testing does not significantly shorten time to disposition among patients with an influenza-like illness. Am J Emerg Med. 2018 Aug 07. PMID: 30107967
- Hall, G., Kurosawa, S., Stearns-Kurosawa, D.J. “Dextran Sulfate Sodium Colitis Facilitates Colonization with Shiga Toxin-Producing Escherichia coli: a Novel Murine Model for the Study of Shiga Toxicosis”, Infection and Immunity, 86(11): pp, 2018, in press
Pathology & Laboratory Medicine News Items – July 2018
CONGRATULATIONS: The Accreditation Committee of the College of American Pathologists (CAP) has awarded accreditation to the Department of Pathology and Laboratory Medicine based on the results of our recent on-site inspection. We congratulate everyone within our department on a job well done because this is truly a team effort!
Bravo to our own Liz Duffy!
Liz Duffy also gave an oral presentation at the Annual Association of Pathology Chairs in Coronado, CA on July 18th, 2018 on her work “Pathology’s Role in Biospecimen Science: A Study of Preanalytic Variables’ Impact on Thrombosis Biomarkers”
Dr. Zach Hunter, a graduate of our Pathology Masters AND PhD Programs, is now an Instructor of Medicine at Boston’s Dana-Farber Institute. Zach completed his thesis work in the Steven Treon Lab at MGH. Recently :
- Dr. Hunter received the Robert A. Kyle Award, one of the highest honors in his field
- As well as an American Society of Clinical Oncology Scholar Award, regarded as one of the most prestigious awards in hematology
Dr. Susan Winandy was awarded a CTSI pilot grant to study a ""New pathway regulating the harmful inflammatory phenotype of T cells". BRAVO!
Troy Sanders, a Masters student in the MAMS program has joined the Winandy Lab. He will be working on defining a new mechanism underlying the control of the inflammatory program in human T cells
Dr. Anna Belkina just got back from presenting an invited seminar at the University of Washington Department of Immunology Seminar Series on July 12; “Revealing disease phenotypes with computational analysis of high-dimensional flow cytometry data”
Dr. Nader Rahimi and Dr. Daniel Remick were awarded a CTSI pilot grant to study the role of IGPR-1 in sepsis. The goal of this proposed study is to investigate the role of IGPR-1 in the vascular leakage associated with sepsis. Sepsis is the second leading cause of death in non-coronary intensive care units, highlighting a significant unmet clinical need.
Dr. Nickolas Crossland was accepted into the Optical Microscopy & Imaging Course hosted by the Marine Biological Laboratory. This 9-day course to be held August 20-30th is highly competitive and is limited to 24 participants to ensure a truly interactive, hands-on experience. It consists of interrelated lectures, laboratory exercises, demonstrations, and discussions that will enable the participants to obtain and interpret high quality microscope data, to understand and assess potential artifacts, to perform quantitative optical measurements, and to generate digital images for documentation and analysis that accurately present the data. Topics to be covered can be found here (http://www.mbl.edu/education/courses/optical-microscopy-imaging/).
Dr. Daniel Remick was a Participant at the Pathology Advocating for Academic Pathology Discussion Group, Association of Pathology Chairs 2018 Annual Meeting
Dr. Remick was also an Invited Speaker, New Pathology Chairs Bootcamp, When, Why, and How to Transition from Being a Chair Participant, Pathology Advocating for Academic Pathology Discussion Group, Association of Pathology Chairs 2018 Annual Meeting
Also from Dr. Remick:
A Wiggers-Bernard Conference on Pre-clinical models of sepsis was held in Vienna, Austria in May, 2017. Four manuscripts are being published in the peer-reviewed literature detailing the conclusions of the conference. All of the manuscripts were recently accepted for publication in the journal Shock
- MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTIPSS): AN INTERNATIONAL EXPERT CONSENSUS INITIATIVE FOR IMPROVEMENT OF ANIMAL MODELING IN SEPSIS
- Marcin F. Osuchowski, Alfred Ayala, Soheyl Bahrami, Michael Bauer, Mihaly Boros, Jean-Marc Cavaillon, Irshad H. Chaudry, Craig M. Coopersmith, Clifford S. Deutschman, Susanne Drechsler, Philip Efron, Claes Frostell, Gerhard Fritsch, Waldemar Gozdzik, Judith Hellman, Markus Huber-Lang, Shigeaki Inoue, Sylvia Knapp, Andrey V. Kozlov,* Claude Libert, John C. Marshall, Lyle L. Moldawer, Peter Radermacher, Heinz Redl, Daniel G. Remick, Mervyn Singer, Christoph Thiemermann, Ping Wang, W. Joost Wiersinga, Xianzhong Xiao, and Basilia Zingarelli in press, Shock
- PART I: MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR STUDY DESIGN AND HUMANE MODELING ENDPOINTS.
- Basilia Zingarelli, Craig M. Coopersmith, Susanne Drechsler, Philip Efron, John C. Marshall, Lyle Moldawer, W. Joost Wiersinga, Xianzhong Xiao, Marcin F. Osuchowski, Christoph Thiemermann in press, Shock
- PART II: MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR TYPES OF INFECTIONS AND ORGAN DYSFUNCTION ENDPOINTS.
- Claude Libert, Alfred Ayala, Michael Bauer, Jean-Marc Cavaillon, Clifford Deutschman, Claes Frostell, Sylvia Knapp, Andrey V. Kozlov, Ping Wang, Marcin F. Osuchowski, Daniel G. Remick in press, Shock
- PART III: MINIMUM QUALITY THRESHOLD 1 IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR FLUID RESUSCITATION AND ANTIMICROBIAL THERAPY ENDPOINTS.
- Judith Hellman, Soheyl Bahrami, Mihaly Boros, Irshad Chaudry, Gerhard Fritsch, Waldemar Gozdzik, Shigeaki Inoue, Peter Radermacher, Mervyn Singer, Marcin F. Osuchowski, Markus Huber-Lang in press, Shock
Joseph Tashjian, a Pathology master student working with Dr. Mostafa Belghasem, has been selected to participate in “Kidney STARS” 2018 program organized by the American Society of Nephrology (ASN). Joseph also received a $1000 travel grant from ASN to attend Kidney Week 2018.
Dr. Mostafa Belghasem was invited by the Evans Center for Interdisciplinary Biomedical Research to present at the monthly ARC/Cardio seminar on July 24th 2018. The lecture topic:” Murine Models of Renal Disease: Analysis of Thrombotic Tendencies”
Greg Hall, DVM, PhD (Kurosawa Lab) successfully defended his Thesis, “Dextran sulfate sodium colitis facilitates murine colonization by Shiga toxin-producing E. coli: A novel model for the study of Shiga toxicosis” on Tuesday, July 24th; Bravo Greg!!
Gregory Hall, DVM, PhD and his PIs, Dr. Shinichiro Kurosawa and Dr. Deborah Stearns-Kurosawa
Dr. & Mrs. Greg Hall and family, 3-yo Cora and 7-week old Maggie celebrating with dad
Konditor Meister Celebration in Dr. Hall's honor!!!
- Juan R. Mella, Arthur F. Stucchi, Elizabeth R. Duffy, Daniel G. Remick; Neurokinin-1 Receptor Deficiency Improves Survival in Murine Polymicrobial Sepsis Through Multiple Mechanisms in Aged Mice; in press, Shock
- Steinbuck MP, Winandy S. A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells. Front Immunol. 2018 Jun 1;9:1230. doi: 10.3389/fimmu.2018.01230. eCollection 2018. Review
- Kartha VK1,2, Alamoud KA3, Sadykov K3, Nguyen BC3, Laroche F4, Feng H4, Lee J5, Pai SI5, Varelas X6, Egloff AM7, Snyder-Cappione JE8,9, Belkina AC8, Bais MV3, Monti S1,2, Kukuruzinska MA10; “Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer” https://www.ncbi.nlm.nih.gov/pubmed/30029671. Genome Med. 2018 Jul 20;10(1):54. doi: 10.1186/s13073-018-0569-7. PMID: 30029671
- Remick DG, Ayala A, Chaudry I, Coopersmith CM, Deutschman C, Hellman J, Moldawer L, Osuchowski M. Premise for Standardized Sepsis Models. Shock. 2018. doi: 10.1097/SHK.0000000000001164. PubMed PMID: 29877959