Viral Molecular Biology
Virus/Host interaction; viral domination of protein synthesis; antiviral compounds, systems biology of viral hemorrhagic fever, novel approaches to virus detection.
Host factor-based therapy development and infection mechanism for filoviruses and other high containment viruses
Enveloped Virus Entry Mechanisms; Innate Immune Evasion Mechanisms; Inflammation & HIV; Nanotherapeutics
Hemorrhagic fever viral pathogenesis, animal model development, utilization of implantable telemetry for real-time physiologic data, advanced development of medical countermeasures
Host response to filovirus infection; molecular mechanisms of filovirus replication and transcription
HIV transmission pathogenesis and role of antibodies in protecting against infection
Molecular biology of HIV-1; the role of virus-host cell interactions in pathogenesis