Subunit Vaccine for Nipah and Hendra Viruses Shows Protection

Nipah and Hendra viruses are newly recognized zoonotic paramixoviruses that have resulted in numerous outbreaks in Australia and Southeast Asia, and are highly lethal in humans. In a recent study published in Science Translational Medicine, Katharine Bossart and colleagues report that a vaccine using a soluble viral G glycoprotein afforded complete protection again Nipah virus challenge in a nonhuman primate model, bolstering support for human clinical trials. See commentary in Science.