Previous Trainee Seminars and Journal Clubs

Spring 2021
January 25 STUDENT SEMINARS (Remote only presentations)
“Uncovering the Pro-viral Function of the Aedes aegypti Protein AAEL002675.”
Alexander Gold, Douam Lab
and
“Innate Immune Response to SARS-CoV-2 in Macrophages”
Sallieu Jalloh, Gummuluru Lab
February 1 JOURNAL CLUB (Remote only presentation)
Nelde, A. et al. SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition. Nature Immunology 22:74-85, 2021. https://pubmed.ncbi.nlm.nih.gov/32999467/
Presenter: David Bean
February 8 NO SEMINAR
February 22 JOURNAL CLUB (Remote only presentation)
Leist, S.R., et al., A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell, 2020. 183(4): p. 1070-1085.e12.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510428/
Presenter: Nathan Sanders
March 1 JOURNAL CLUB (Remote only presentation)
Wahl, Al, LE Gralinski, CE Johnson, et al. SARS-CoV-2 Infection is Effectively Treated and Prevented by EIDD-2801. Nature (2021) https://doi.org/10.1038/s41586-021-03312-w.
Presenter: Devin Kenney
March 15 STUDENT SEMINARS (Remote only presentations)
“Potential involvement of cellular protein PABP in respiratory syncytial virus mRNA polyadenylation”
Victoria Kleiner, Fearns Lab
and
Immunological Consequences of Defective HIV Infection in Macrophages”
Jeffrey Kuniholm, Henderson Lab
March 22 STUDENT SEMINARS (Remote only presentations)
“Investigation of Effects of Opioids on HIV Replication and Latency”
Binita Basukala, Henderson Lab
and
“Biomarkers of Mortality in Lassa Fever”
Jamie Strampe, Connor Lab
March 29 POSTDOC/RESEARCH SCIENTIST SEMINARS (Remote only presentations)
“Modeling SARS-CoV-2 Infection with Human Pluripotent Stem Cell-Derived Intestinal Organoids Reveals a Common Epithelial Inflammatory Response”
Adam Hume, Mühlberger Lab
and
“No way to Escape: CD169 and Pathogenic Viruses”
Judith Olejnik, Mühlberger Lab
Tuesday, March 30, at 11:00 am DISSERTATION DEFENSE SEMINAR
“Linoleic Acid-mediated Regulation of T Cell Cytokine-subset Composition in Type 1 Diabetes”
Jaileene Hernandez Escalante
April 5 JOURNAL CLUB (Remote only presentation)
McCarthy, K.R. et al. Recurrent Deletions in the SARS-CoV-2 Spike Glycoprotein Drive Antibody Escape. Science 371(6534):1139-1142, 2021. https://science.sciencemag.org/content/371/6534/1139
Presenter: Brianna Close
April 12 JOURNAL CLUB (Remote only presentation)
Banadyga, L., et al. Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment is Associated with Glycoprotein Mutations within the Fusion Loop. mBio 12(1):e01438-20, 2021.
https://mbio.asm.org/content/12/1/e01438-20.long
Patrick
 Keiser, Davey Lab
April 26 STUDENT SEMINARS (Remote only presentations)
Josiane Fofana
, Gummuluru Lab
and
“Functional Characterization of the Expanded PD-1+TIGIT+ CD4+ T Cell Population in Systemic Sclerosis”
Victoria Volfson Sedletsky, Dooms Lab
Friday, April 30
@ 2:00 pm
DISSERTATION DEFENSE SEMINAR
“Induced Pluripotent Stem Cell Based Modeling of Gastrointestinal Disease using Human Intestinal Organoids”
Aditya Mithal
July 28 DISSERTATION DEFENSE SEMINAR
“Investigating the Role of Antibody-Dependent Cellular Cytotoxicity in the Prevention of Mother-to-Child Transmission of HIV-1 Through Breastfeeding”
Allison Thomas
Fall 2020
Tuesday,
September 8,
1:00 PM
DISSERTATION DEFENSE SEMINAR
Eric Brownhill
“Compromised Metabolic Function and Dysregulated Induction of Type 1 Interferon Promote Susceptibility in a Model for Tuberculosis Infection”
September 21 STUDENT SEMINARS
“Pluripotent Stem Cell Derived Organoid-Based Modeling of Intestinal SARS-CoV2 Infection”
Aditya Mithal, Mostoslavsky Lab
and
“An ELISA Protocol with Resolution at High Sample Concentration Reveals Reactive Antibodies to SARS-CoV-2 in Unexposed Individuals”
Rachel Yuen, Cappione Lab
Thursday,
September 24,
11:00 AM
DISSERTATION DEFENSE SEMINAR
“The Establishment and Function of Lung Resident Memory B Cells after Bacterial Respiratory Infection”
Kimberly Barker
September 28 NO SEMINAR
October 5 STUDENT QUALIFYING EXAM SEMINARS
“Characterizing the Trafficking and Fusion of Ebola Virus in the Endolysosomal System”
Callie Donahue
and
“Comparative Analysis of Cellular Stress Responses in Filovirus Infections”
Ellen Suder
October 12 NO SEMINAR
October 19 NO SEMINAR
October 26 STUDENT SEMINARS
“Effects of Liver Activity on the Lung Immune Landscape”
Christine Odom, Quinton Lab
and
“Antibody Dependent Cellular Cytotoxicity (ADCC) as a Correlate of Protection against Mother-to-Child Transmission of HIV-1”
Allison Thomas, Sagar Lab
November 2 STUDENT SEMINARS
“Data Wrangling, Making Sense of Giant Data”
Fumiaki Aihara, Kepler Lab
and
“Lung Resident Memory B Cell Dynamics in Response to Pneumococcal Infection”
Neelou Etesami, Mizgerd Lab
November 9 JOURNAL CLUB
Li, X., et al. 2018. H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2. Cell Research 28:157-171.
Presenter: Stephen Ross
November 16 STUDENT SEMINARS
“Recombinant RSV Containing a Cre Recombinase: A Tool to Study Previous Infection”
Michael Breen, Fearns Lab
and
“Determining the Role of IL-7 Signaling in Type I Diabetes”
Albert Jones, Dooms Lab
November 23 SENIOR RESEARCH SCIENTIST
“Establishment and Characterization of a SARS-CoV-2 Infection Model of iPSC-Derived Alveolar Type 2 Cells”
Adam Hume, Mühlberger Lab
November 30 JOURNAL CLUB
Schultz, P. et al. 2018. MicroRNA-122 Amplifies Hepatitis C Virus Translation by Shaping the Structure of the Internal Ribosomal Entry Site. Nat. Comm. 9:2613.
Presenter: Elizabeth Chavez
December 7 STUDENT SEMINARS – REMOTE ONLY
“Investigating the Role of Active Tuberculosis Co-Infection on Plasma Breadth and Potency in Chronic HIV-1 Patients”
Bukola Adeoye, Sagar Lab
and
“T-Cell Landscape of Heterotypic Immune Lungs”
Carolina Lyon De Ana, Mizgerd Lab
December 14 STUDENT SEMINARS
“Development of a Sudan Virus Minigenome System to Study Nucleoprotein Mutations”
Laura Avena, Griffiths Lab
and
“Characterizing the Sudan ebolavirus Variant Swarm during Serial Passage”
Jacquelyn Turcinovic, Connor Lab
Spring 2020
January 27 STUDENT SEMINARS
“The Influence of The Lung Virome on Pulmonary B cells”
Fumiaki Aihara, Kepler Lab
and
Characterizing the Lung B Memory Cell Population After Respiratory Viral Infection”
Michael Breen, Fearns Lab
February 3 JOURNAL CLUB
Callie Donahue, Davey Lab
Martini, F., Arone, C., Hasset, A., Hall, W. W. & Sheehy, N. The ESCRT-0 Protein HRS Interacts with the Human T Cell Leukemia Virus Type 2 Antisense Protein APH-2 and Suppresses Viral Replication. J. Virol. 94, e01311-19, 2019. PMID: 31597781
February 10 QUALIFYING EXAM SEMINAR
“Characterization of PD-1+TIGIT+ CD4+ T Conventional Cells in Systemic Sclerosis and Their Contribution to Fibrosis”
Victoria Volfson Sedletsky, Dooms Lab
February 24 JOURNAL CLUB
Josiane Fofana, Gummuluru Lab
Thurs, Feb 27
@ 9:00 AM
Location: TBA
DISSERTATION DEFENSE SEMINAR
“Discovery, Characterization, and Ligand Specificity Engineering of a Novel Bacterial Transcription Factor Inducible by Progesterone”
R Cooper Baer
March 2 STUDENT SEMINARS
“Investigating the Role of Tuberculosis Disease on Humoral Immunity in Ugandans Living with HIV-1”
Bukola Adeoye, Sagar Lab
and
“STAT3-Induced Liver Activity Remodels the Lung Landscape to Fortify Pulmonary Disease”
Christine Odom, Quinton Lab
March 16 ***C A N C E L E D***
POSTDOC/RESEARCH SCIENTIST SEMINARS
“Characterizing a Clinically Identified Mutation in the Ebola Virus Glycoprotein”
Scott Seitz, Connor Lab
and
“Filovirus Glycoproteins and TLR4”
Judith Olejnik, Mühlberger Lab
March 23 MOVED TO MAY 4
March 30 JOURNAL CLUB
Victoria Volfson Sedletsky, Dooms Lab
Taylor, DK et al. T Follicular Helper-Like Cells Contribute to Skin Fibrosis. Sci. Transl. Med. 10(431):eaaf5307, 2018. PMID 29514998
April 6 STUDENT SEMINARS
“The Function of Extracellular Vesicles and their Cargo during Dengue Virus Infection”
Alexander Gold, Colpitts Lab
and
“Memory CD4+ T Cell Landscape after Lung Recovery from Pneumococcal Pneumonia”
Carolina Lyon de Ana, Mizgerd Lab
April 13 STUDENT/RESEARCH TECHNICIAN SEMINARS
“Investigation of Effect of Chronic Opioid Misuse on HIV Pathogenesis and Latency Establishment”
Binita Bashukala, Henderson Lab
and
“Distinct Roles of Gamma Delta T Cell Subsets in HIV and Aging-Associated Inflammation”
Riley Pihl, Flow Core
April 27 NO SEMINAR
May  4 STUDENT SEMINARS
“Mechanisms of HIV-1 RNA-Induced Activation of Microglia”
Sallieu Jalloh
, Gummuluru Lab
and
“Regulation of Autoreactive T Cell Fitness and Cytokine-Subset Distribution by n-6 Polyunsaturated Fatty Acids”
Jaileene Hernandez Escalante, Dooms Lab
Tuesday, May 12
@ 12:00 pm
DISSERTATION DEFENSE SEMINAR
“Ebola Virus Induces a Type I Interferon Response in Induced Pluripotent Stem Cell-Derived Hepatocytes”
Whitney Manhart
Thursday,
June 25
@ 1:00 pm
DISSERTATION DEFENSE SEMINAR
“Cell-to-Cell Transmission and Intrinsic Mechanisms that Influence HIV Infection”
Kyle Pedro
Fall 2019
Thurs, Sept 12
@ 1:00 PM
in L110
DISSERTATION DEFENSE SEMINAR
Alexander Barron
“Perivascular Fibroblast Activation States in Human Skin Diseases”
September 23 JOURNAL CLUB
Carolina Lyon de Ana
Vesely, M.C.A. et al. 2019. Effector TH17 Cells Give Rise to Long-Lived TRM Cells that are Essential for an Immediate Response Against Bacterial Infection. Cell 178:1176-1188.
September 30 STUDENT SEMINARS
Whitney Manhart, Mostoslavsky and Mühlberger Labs
“Comparison of Human and Rousettus aegyptiacus Host Responses to Filovirus Infection”
and
Aditya Mithal, Mostoslavsky Lab
“iPSC modeling of Tissue Resident Macrophage Function in Crohn’s Disease Pathogenesis”
October 7 NO SEMINAR
October 21 STUDENT SEMINARS
Kimberly Barker, Mizgerd Lab
“Resident Memory B Cells are an Important Component of Lung Adaptive Immunity”
and
Allison Thomas, Sagar Lab
“A New Cell Line more Amenable to Access HIV-1 Antibody Dependent Cellular Cytotoxicity Against Broad Range of Variants”
October 28 JOURNAL CLUB
Victoria Kleiner
Gilman, M.S.A. et al. 2019. Structure of the Respiratory Syncytial Virus Polymerase Complex. Cell 179:193-204.
November 4 STUDENT SEMINARS
Albert Jones, Dooms Lab
“Determining the Role of IL-7 Signaling in Type 1 Diabetes”
and
Sarah Nodder, Gummuluru Lab
“HIV-2 Vpr Suprpresses a Type III IFN Response in Monocyte-Derived Dendritic Cells”
Friday, Nov 15
@ 12:30 PM
in L110
DISSERTATION DEFENSE SEMINAR
Tessa Cressey
“RNA Synthesis Initiation by the Nonsegmented Negative-Sense RNA Virus Polymerases”
November 18 JOURNAL CLUB
Ellen Suder
Nikolic, J. et al. 2017. Negri Bodies are Viral Factories with Properties of Liquid Organelles. Nat. Comm. 8:58-70
Friday, Nov 22
@ 12:00 PM
DISSERTATION DEFENSE SEMINAR
Molly Braun
“Multifunctional Roles of the Respiratory Syncytial Virus Transcription and Genome Replication Machinery”
November 25 STUDENT SEMINARS
Eric Brownhill, Kramnik Lab
“Dysregulation of Type 1 Interferon Compromises Metabolic Function and Promotes Susceptibility in an in vitro Model of Tuberculosis Infection”
and
Rachel Yuen, Wetzler Lab
“TLR-Based Adjuvant Enhancement of the Germinal Center Reaction”
December 9 POSTDOC/RESEARCH SCIENTIST
Adam Hume, Mühlberger Lab
“Ender’s Game: Finding Functional Lloviu Virus Genome Ends”
and
Rebecca Johnson, Griffiths Lab
“Characterization of Ebola Virus Defective Genomes”
Spring 2019
February 4 Journal Club Alexander Gold Beerli, C., et al. 2018. Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility. Nat. Microbiol. [Epub ahead of print].
11 Student Seminars Whitney Manhart
(Mostoslavsky and
Mühlberger Labs)
and
Aditya Mithal
(Mostoslavsky Lab)
“Development of an Ebola Virus Infection Model using iPSC-Derived Hepatocytes”
and
“iPSC Modeling of Tissue Resident Macrophage Function in Crohn’s Disease Pathogenesis”
18 No Seminar
25 Journal Club Sallieu Jalloh Daniels, B.P. et al. 2019. The nucleotide sensor ZBP1 and kinase RIPK3 induce the enzyme IRG1 to promote an antiviral metabolic state in neurons. Immunity 50:64-76.
March 4 No Seminar
11 Journal Club Christine Odom Pillponsky, A.M. et al. 2019. Basophil-Derived tumor necrosis factor can enhance survival in a sepsis model in mice. Nat. Immunol. 20:129-140.
18 Student Seminars Michael Breen
(Fearns Lab)
and
Allison Thomas
(Sagar Lab)
“Characterizing the Lung B Memory Cell Population after Respiratory Viral Infection”
and
“Investigating the Role of ADCC in the Prevention of Mother-To-Child Transmission of HIV-1”
Friday,
Mar 22, 12 PM in L110
Dissertation Defense
Seminar
Matthew Gagne “Cellular Mechanisms that Establish HIV-1 Latency in CD4+ T Cells and the Potential for their Manipulation as a Therapeutic Strategy”
25 Journal Club Laura Avena Santiana, M. et al. 2018. Vesicle-Cloaked Virus Clusters are Optimal Units for Inter-organismal Viral Transmission. Cell Host Microbe 24(2):208-220.
April 1 Journal Club Bukola Adeoye Castellano, P. et al. 2019. HIV Infection and Latency Induce a Unique Metabolic Signature in Human Macrophages. Sci. Rep. 9(1):3941-3954.
8 No Seminar
15 No Seminar
22 Student Seminars Fumiaki Aihara
(Kepler Lab)
and
Albert Jones
(Dooms Lab)
“The Influence of the Lung Virome on Pulmonary B Cells”
and
“Determining the Role of IL-7 Signaling in Type 1 Diabetes”
29 Journal Club Neelou Etesami Velazquez, E., et al. 2019. Endogenous Enterobacteriaceae Underlie Variation in Susceptibility to Salmonella Infection. Nat. Microbiol. [epub ahead of print].
June 12  at
11:00 a.m.
Qualifying Exam Seminars Sallieu Jalloh
and
Alexander Gold
“Elucidating the Mechanism and Consequences of HIV-1-Induced Innate Immune Activation in Microglia”
and
“The Role of Exosomes in Human to Mosquito Transmission of Dengue Viruses”
14 at
11:00 a.m.
Qualifying Exam Seminars Neelou Etesami,
Jeffrey Kuniholm,
and
Carolina Lyon de Ana
“Characterization of Outer Membrane Vesicles and PorB1B as Novel Gonococcal Vaccine Candidates,”

“The Effects of TLR Ligand Vaccine Adjuvants on T Cell Memory”
and
“The T Cell Landscape of Heterotypic Immune Lungs”

July 1 Qualifying Exam Seminar Christine Odom “Hepatocyte STAT3-Dependent Mechanisms of Limiting Pneumonia Susceptibility During Sepsis”
10 Qualifying Exam Seminar Bukola Adeoye Mycobacterium tuberculosis (MTB) Infection Impacts Human Immunodeficiency Virus-1 (HIV-1) Specific Humoral Responses in HIV-1/MTB Coinfection”
Fall 2018
September 17 Student Seminars Alexander Barron
(Browning Lab)
and
Matthew Gagne
(Henderson Lab)
“T Cell Accumulation Accompanies Vascular Adventitial Fibroblast Specialization in the Inflamed Human Dermis”
and
“Strength of T Cell Signaling Regulates HIV-1 Replication and Establishment of Latency”
24 No Seminar
October 1 Student Seminar R Baer
(Galagan Lab)
“Development of a Cell-Based Steroid Biosensor for Directed Evolution of a Bacterial Progesterone Sensitive Transcription Factor”
8 No Seminar
15 Journal Club Jaileene Hernandez Escalante Akondy, R.S., et al. 2017. Origin and Differentiation of Human Memory CD8 T Cells after Vaccination. Nature 552:362-367.
22 Student Seminars Tessa Cressey
(Fearns and Mühlberger Labs)
and
Kyle Pedro
(Henderson Lab)
“Structural Determinants of the RSV Polymerase Involved in Coordinating the RNA Synthesis Initiation Complex”
and
“Investigating the Role of Novel HIV-2 Transcription Factors”
29 Journal Club Fumiaki Aihara Onder, L. et al. 2017. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity 47:80-92.
November 5 Student Seminars Molly Braun
(Fearns Lab)
and
Rachel Yuen
(Wetzler Lab)
“RNA Binding Properties and Localizations of the RSV Transcription Elongation Factor, M2-1”
and
“T Follicular Helper Cell and Germinal Center B Cell Responses Induced by TLR-Based Adjuvants”
12 No Seminar
19 Journal Club Jeffrey Kuniholm Zhang, Q. et al. 2018. Blockade of the Checkpoint Receptor TIGIT Prevents NK cell Exhaustion and Elicits Potent Anti-Tumor Immunity. Nat. Immunol. 19:723-732.
26 Student Seminars Kimberly Barker
(Mizgerd Lab)
and
Sarah Nodder
(Gummuluru Lab)
“Pneumococcal Exposures Elicit Lung Plasma Cells and Memory B Cells Poised to Secrete Class-Switched Antibodies”
and
“Investigating the Role of HIV-2/SIVmac Vpr in Monocyte-Derived Dendritic Cells”
December 3 Journal Club Aditya Mithal De Schepper, S. et al. 2018. Self-Maintaining Gut Macrophages are Essential for Intestinal Homeostasis. Cell 175:400-415.
10 Student Seminars Eric Brownhill
(Kramnik Lab)
and
Jaileene Hernandez Escalante
(Dooms Lab)
Interferon Immunopathology: Evaluating the Role of RNA-Dependent Protein Kinase (PKR) in Susceptibility to Tuberculosis”
and
“Regulatino of IL-10 Producing T cells by Polyunsaturated Fatty Acids”
Spring 2018
January 29 Microbiology Journal Club Michael Breen McCarthy, K.R. et al. 2018. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses are Abundant in Adult Human Repertoires. Immunity 48(1):174-184.
February 5 Immunology Journal Club Fumiaki Aihara Grist, J.T. et al. 2018. Extracellular Lactate: A Novel Measure of T Cell Proliferation. J. Immunol.  
12 No Seminar
Friday,
Feb 16,
12:00 PM
in X714
Dissertation Defense Seminar Ludy Registre “Examination of the Role of Envelope Directed Antibodies on Co-Receptor Usage in HIV-1B Infection”
19 No Seminar
Tuesday,
Feb 20,
1:00 PM
Dissertation Defense Seminar Michelle Fleury “Expression and Function of Co-Inhibitory Receptors PD-1, TIGIT, TIM-3, and LAG-3 in Systemic Sclerosis”
26 Student Seminars Whitney Manhart
(Mostoslavsky and Mühlberber Labs)
and
Rachel Yuen
(Wetzler Lab)
“Investigating a Virus that Doesn’t Exist: Generating a Minigenome System for Lloviu Virus”
and
“The Effect of Adjuvants on the Germinal Center Response and Development of Humoral  Immunological Memory”
March 5 Microbiology Journal Club Allison Thomas Turner, D.L. et al. 2018. Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma. J. Immunol. 200(5):1561-1569.
12 Student Seminars Eric Brownhill
(Kramnik Lab)
and
Jaileene Hernandez Escalante
(Dooms Lab)
“Interferon Immunopathology: Evaluating the Drivers of Susceptibility to M. tuberculosis Infection”
and
“Investigating the Influence of Fatty Acids on T1D Autoreactive Prone T Cells”
19 No Seminar
26 Student Seminars Kimberly Barker
(Mizgerd Lab)
and
Sarah Nodder
(Gummuluru Lab)
“Investigating B Cell Contributions to Heterotypic Anti-Pneumococcal Immunity”
and
“Unintegrated HIV DNA: Dead End or Secret Reservoir?”
April 2 No Seminar
Tuesday, Apr 3,
10:00 AM
Dissertation Defense Seminar Ian Francis “The Characterization of Novel Transgenic Murine Models of Neisseria Gonorrhoeae Infection and Development of a Natural Outer Membrane Vesicle Anti-Gonococcal Vaccine Candidate”
Thursday, Apr 5,
11:00 AM
Dissertation Defense Seminar Stephanie Pavlovich “Genomic Analysis and Examination of Innate Antiviral Immunity in the Egyptian Rousette Bat”
9 Immunology Journal Club Alexander Barron Viera, S.M. et al. Translocation of a gut Pathobiont Drives Autoimmunity in Mice and Humans. Science 359(6380):1156-1161.

Accompanying Perspective Article
Citi, S. Intestinal Barriers Protect Against Disease. Science 359(6380):1097-1098.

16 No Seminar
23 Postdoctoral Seminars John Ruedas
(Connor Lab)
and
Barbara Ludeke
(Fearns Lab)
“Change is Happening: Investigation of a Series of Growth-Adaptive Mutations Emerging in the Ebola Makona Glycoprotein”
and
“Building Blocks for a Non-Isotopic Assay for RSV RNA Polymerase Activity”
Wednesday,
Apr 25,
2:00 PM
Dissertation Defense Seminar Sila Ataca “Biophysical Characterization of Affinity Maturation in the Human Response to Anthrax Vaccine”
30
May 14 Qualifying Exam Seminars Albert Jones
and
Aditya Mithal,
and
Allison Thomas
“Impacts of IL-7 Signaling Inhibition on Type 1 Diabetes”
and
“Defective Macrophages- Investigating a New Paradigm of Crohn’s Disease Pathogenesis”
and
“Investigating the Role of Antibodies Capable of Mediating Cellular Cytotoxicity in Mother-to-Child-Transmission of HIV-1”
Tuesday,
May 15,
12:00 PM
in L112
Qualifying Exam Seminars Fumiaki Aihara
and
Michael Breen
“The Influence of the Lung Virome on Pulmonary B Cells”
and
“Characterizing the Lung B Memory Cell Population after Respiratory Viral Infection”
Fall 2017
September 25 Microbiology Journal Club Matthew Gagne Foster TL, et al. 2016. Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction. Cell Host Microbe. 20(4):429-442.
October 2 Student Seminars Alexander Barron
(Browning Lab)
and
Matthew Gagne
(Henderson Lab)
“VCAM Expression by Vascular Adventitial Fibroblasts Correlates with Perivasicular T Cell Accummulation in Human Skin Diseases”
and
“The Effects of Differential T Cell Signaling on HIV Transcription and Latency”
9 No Seminar
16 Immunology Journal Club Whitney Manhart Jaitin DA, et al. 2016. Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq. Cell 167(7):1883-1869.
23 No Seminar
30 Inflammation Journal Club Molly Braun Takata, MA et al. 2017. CG Dinucleotide Suprpression Enables Antiviral Defence Targeting non-self RNA. Nature 550(7674):124-127.
November 6 Student Seminars Tessa Cressey
(Fearns/Muhlberger Labs)
and
Kyle Pedro
(Henderson Lab)
“Initiation Mechanisms of the RSV Polymerase”
and
“The Contribution of DC-Mediated and T Cell Receptor Signaling to HIV trans-infection”
13 Microbiology Journal Club Albert Jones Naik, S et al. 2017. Inflammatory Memory Sensitizes Skin Epithelial Stem Cells to Tissue Damage. Nature 26:550(7677):475-480.
20 Postdoctoral Seminars Leena Panneerseelan-Bharath
(Microbiology)
and
Antoine Guillon
(Pulmonary)
“Metformin Treatment for Aging-Induced Immune Cell Dysfunction”
and
“Are Tissue-Resident Lung Macrophages Remodeled or Reprogrammed by Heterotopic Immunity?”
27 Immunology Journal Club Gregory Hall Rosshart, SP et al. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance. Cell , Volume 171 , Issue 5 , 1015 – 1028.e13.
December 4 Student Seminars R Baer
(Galagan Lab)
and
Molly Braun
(Fearns Lab)
“Discovery and Characterization of a Novel Progesterone Sensitive Bacterial Transcription Factor”
and
“Factors Affecting RNA Elongation by the RSV Polymerase”
11 Inflammation Journal Club Eric Brownhill Lachmandas E et al. Microbial Stimulation of Different Toll-like Receptor Signalling Pathways Induces Diverse Metabolic Programmes in Human Monocytes. Nat. Microbiol. 2:16246.
Spring 2017
January 9 Microbiology Journal Club Sila Ataca Briney, B. et al. 2016. Tailored Immunogens Direct Affinity Maturation Toward HIV Neutralizing Antibodies. Cell 166:1459-1470.
16 No Seminar
23 Immunology Journal Club Kyle Pedro Park, R.J. et al. 2016. A Genome-Wide CRISPR Screen Identifies a Restricted set of HIV Host Dependency Factors. Nat. Genetics [Epub ahead of print].
30 Inflammation Journal Club Christina Lisk Hutton, A.J. et al. 2017. Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells. J. Immunol. 198:110-118.
February 6 Postdoctoral Fellow Seminars John Ruedas
(Connor Lab)
and
Sarah Shearer
(Fearns Lab)
“Common Occurrence of Tissue-Culture Adapted Ebola Viruses Caused by a Single Mutation in the Glycoprotein Fusion Loop”
and
“Initiation of Respiratory Syncytial Virus Transcription and Replication”
13 Student Seminars Molly Braun
(Fearns Lab)
and
Matthew Gagne
(Henderson Lab)
“The Multifunctional Role of a Domain in the RSV Polymerase”
and
“The Effects of Differential T Cell Stimulation on HIV Infection and Reactivation”
20 No Seminar
27 Microbiology Journal Club Rachel Yuen Deriu, E. et al. 2016. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS Pathogens 12(5): e1005572.
March 6 Immunology Journal Club Matthew Gagne Druzd, D. et al. 2017. Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses. Immunity 46:120-132.
13 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
20 Postdoctoral Fellow Seminar Dequina Nicholas
(Nikolajczyk Lab)
and
Judith Olejnik
(Mühlberger Lab)
“Fatty Acid Uptake Unexpectedly Supports a Th17 Cytokine Signature in Type 2 Diabetes (T2D) Inflammation”
and
“Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Response in Human Macrophages”
27 Student Seminars Tessa Cressey
(Fearns and Muhlberger Labs)
and
Ludy Registre
(Sagar Lab)
“Relating Polymerase Structure to Initiation of RNA Synthesis”
and
“CXCR4 Variants are Neutralization Resistant Compared to CCR5-Using Viruses in HIV-1B”
April 3 Microbiology Journal Club Kimberley Barker Zipperer, A. et al. 2016. Human Commensals Producing a Novel Antibiotic Impair Pathogen Colonization. Nature 353:511-529.
10 Immunology Journal Club Ian Francis Gury-BenAri, M., et al. 2016. The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome. Cell 166(5):1231-1246.
17 No Seminar
24 Student Seminars R Baer
(Galagan Lab)
and
Kyle Pedro
(Henderson Lab)
“Discovery and Characterization of a Novel Steroid-Sensing Transcription Factor from a Bacterium”
and
“The Contribution of DC-Mediated and T Cell Receptor Signaling to HIV trans-infection”
May 1 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
8 Postdoctoral Fellow Seminars Luis Agosto
(Henderson Lab)
and
Michael Reiser
(Wetzler Lab)
“HIV Latency after Cell-to-Cell Transmission to Restin gCD4+ T Cells”
and
“The TLR Ligand Based Adjuvant, Neisserial Porin PorB, and its Mechanism of Adjuvant Activity”
Monday
May 22 @ 10:00 a.m.
Dissertation Defense Seminar Kaitlin Sawatzki “Examination of the Immunoglobulin Repertoire Before and After Anthrax Vaccine Adsorbed Immunization”
Tuesday
May 23 @ 10:00 a.m.
Qualifying Exam Seminars Jaileene Hernandez-Escalante
and
Rachel Yuen
“Investigating the Lipid Metabolic Dysregulation of T1D Autoreactive T Cells”
and
“Investigating the Role of Adjuvants in the Development of Humoral Immunological Memory”
Thursday May 25 @ 1:00 p.m. Qualifying Exam Seminars Eric Brownhill
and
Whitney Manhart
“Macrophages in TB: A Study in Stress Management”
and
“Development of an Ebola Virus Pathogenesis Model using iPSC-Derived Hepatocytes”
Thursday June 1 @ 10:00 a.m. Qualifying Exam Seminar Sarah Nodder “Investigating Vpr-Mediated DNA Damage Responses during HIV Infection”
Thursday June 22 @ 12:00 p.m. Qualifying Exam Seminar Kimberly Barker “Investigating B Cell Contributions to Naturally-Acquired Heterotypic Immunity to Pneumococcus”
Fall 2016
September 26 at
11:30 AM
Microbiology Student Qualifying Exam Seminar Alexander Barron
(Browning Lab)
“Regulation of Inflammation-Stimulated Protein Transport in Dermal Fibroblasts by Doublecortin-Like Kinase 1”
October 3 Microbiology Journal Club Whitney Manhart Chuong, E.B. et al. 2016. Regulatory Evolution of Innate Immunity Through Co-Option of Endogenous Retroviruses. Science 351:1083-1087.
10 No Seminar
17 Student Seminars Michelle Fleury
(Dooms Lab)
and
Ian Francis
(Wetzler Lab)
“Characterizing Immune Dysfunction in Systemic Sclerosis”
and
“Host Response to Neisseria gonorrhoeae Infection in Female Wild Type Mice is Dictated by the Dominant Sex Hormone”
24 Inflammation Journal Club Cari Meisel Li, W.A. et al. 2016. The Effect of Surface Modification of Mesoporous Silica Micro-Rod Scaffold on Immune Cell Activation and Infiltration. Biomaterials 83:249-256.
31 Immunology Journal Club Emad Arafa Xiong, H. et al. 2016. Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance. Cell 165:679-689.
November 7 Student Seminars Sila Ataca
(Kepler Lab)
and
Stephanie D’Souza
(Kepler Lab)
“Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine”
and
“Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir”
14 Microbiology Journal Club Sarah Nodder Muenchhoff, M et al. 2016. Nonprogressing HIV-infected Children Share Fundamental Immunological Features of Nonpathogenic SIV Infection. Sci Transl Med 8:358ra125.Supplementary Materials.
21 Postdoctoral Seminar Michelle Olsen
(Connor Lab)
and
Kristen Peters
(Connor Lab)
“Mechanisms of Ebolavirus Dependence on Polyamines and Hypusinated-eIF5A”
and
“Early Term Placental Explants as an ex vivo Model of Zika Virus Infection”
28 Inflammation Journal Club Jaileene Hernandez Bengsch, B. et al. 2016. Bioenergetic Insufficiencies due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 are an Early Driver of CD8+ T Cell Exhaustion. Immunity 45:1-16.
December 5 Sr. Research
Scientist
Hisashi Akiyama “Role of Myeloid Cells in HIV-1 Pathogenesis”
12 Immunology Journal Club Gregory Hall Meyer zu Horste, G. et al. 2016. RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression. Cell Reports 16:392-404.
Spring 2016
February 1 Microbiology Journal Club Tessa Cressey Long, J.S. et al. 2016. Species difference in ANP32A underlies influenza A virus polymerase host restriction. Nature, 529(7584), 101–104.
8 No Seminar
Friday, Feb 12 @ 12:00 PM DISSERTATION DEFENSE SEMINAR Krishna Moody “Attenuation of BCR-TLR Responses by FcγRIIB”
15 No Seminar
22 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
29 Student Seminars Michelle Fleury
and
Ludy Registre
“Role of Immunoregulatory Pathways in Systemic Sclerosis”
and
“Neutralization Differences Between CCR5 and CXCR4 Tropic Viruses in HIV-1B Infection”
March Friday, Mar 4 @ 12:00 PM DISSERTATION DEFENSE SEMINAR Emily Nelson “Examination of the Cellular Stress Response and Post-transcriptional Regulation of RNA during Ebola Virus Infection”
7 Inflammation Journal Club Christina Lisk Weisel, F.J. et al. 2016.  A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells. Immunity  44: 116-130.
14 No Seminar
21 Immunology Journal Club Barry Horne Lood, C., et al. 2015. Neutrophil Extracellular Traps Enriched in Oxidized Mitochondrial DNA are Interferogenic and Contribute to Lupus-like Disease. Nat. Med. 22:146-153.
Friday, Mar 25 @ 11:00 AM DISSERTATION DEFENSE SEMINAR Gregory Wasserman “A Discrete Population of Ciliated Cells Express the piRNA Binding Protein MIWI2 to Regulate Lung Inflammation”
28 Student Seminars Matthew Gagne
and
Grace Olinger
“Effects of Differential T Cell-associated Signals on HIV Infection”
and
“Investigating the Duplication Within the Attachment Glycoprotein Gene of Human Respiratory Syncytial Virus (HRSV)”
April 4 Microbiology Journal Club R Baer Westerman, A.J. et al. 2016. Dual RNA-seq Unveils Noncoding RNA Functions in Host-pathogen Interactions. Nature 529:496-501.
11 No Seminar
18 No Seminar
25 No Seminar
May 2 Inflammation Journal Club Margaret Baker Almeida et al. 2015. The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity 43:264-276.
Thursday, May 5 @ 1:00 PM DISSERTATION DEFENSE SEMINAR Munir Mosaheb “Immunological Responses and Mechanisms of Action of the TLR2-ligand Neisserial PorB Vaccine Adjuvant”
9 Immunology Journal Club Matthew Gagne Wang, Z. et al. 2016. CRISPR/Cas9-derived Mutations both Inhibit HIV-1 Replication and Accelerate Viral Escape. Cell Reports 15:481-489.
June Wednesday,
June 1 @ 12:00 PM
Qualifying Exam Seminars Kyle Pedro “The Impact of Signaling from the Infectious Synapse on HIV-1 Infection and the Establishment of Latency”
6 Qualifying Exam Seminars R Baer
and
Molly Braun
and
Tessa Cressey
“Characterization and Directed Evolution of Hormone Sensitive Bacterial Transcription Factors for use in Biosensing Applications”
and
“Factors Affecting Viral Transcription during Respiratory Syncytial Virus Infection”
and
“Investigating Filovirus Replication and Transcription Mechanisms”
13 Trainee Travel Award Seminars Matthew Gagne
and
Kaitlin Sawatzki
Cold Spring Harbor Meeting on Retrovirus
and
Gordon Conference on Antibody Biology and Engineering
Fall 2015
September
NOTE:
Seminar is
12:00-1:30 pm
21 Microbiology Student Qualifying Exam Seminars Sila Ataca “Biophysical Characterization of Immunoglobulins during Affinity Maturation in the Human Response to Anthrax Vaccine”
Stephanie D’Souza “Immunogenomics of the Egyptian Fruit Bat, an Important Viral Reservoir”
Ian Francis “Evaluation of Neisseria gonorrhoeae outer Membrane Vesicles as a Vaccine Candidate for Gonococcal Infection using a Novel Transgenic Mouse Model”
28 Immunology Journal Club Caitlin Miller Grow E.J. et al. Intrinsic Retroviral Reactivation in Human Preimplantation Embryos and Pluripotent Cells. Nature 522(7555):221-225, 2015.
Tuesday
29 @ 11:00 AM
DISSERTATION DEFENSE Fadie Coleman “Influence of Macrophage NF-kB Activation on Pneumococcal Pneumonia”
October 5 Microbiology Journal Club Molly Braun Leung, D.W. et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports 11(3):376-389, 2015.
11 No Seminar
19 Research Scientist Seminar Hisashi Akiyama “Role of CD169/Siglec-1 in HIV-1 Dissemination and Evasion from Antiviral Immune Responses”
26 No Seminar
November 2 Inflammation Journal Club George Papadopoulos Warnatsch, A. et al. Neutrophil Extracellular Traps License Macrophages for Cytokine Production in Atherosclerosis. Science 349:316-320, 2015.
9 Immunology Journal Club Alexander Barron Brunham, R.D. A Chlamydia Vaccine on the Horizon. Science 348:1322-1323, 2015.Stary, G. et al. Vaccines. A Mucosal Vaccine Against Chlamydia trachomatis Generates two Waves of Protective Memory T Cells. Science 348:aaa8205
16 Student Seminars Kaitlin Sawatzki
and
Gregory Wasserman
“Non-Specific Activation of Autoreactive B Cells after Anthrax Vaccination Delays Protection”
and
“Miwi2 Exerts piRNA Independent Regulation of Innate Immunity during Bacterial Pneumonia”
23 Research Scientist Seminar Adam Hume “Marburg Virus VP35 Function in Human and Bat Cells”
30 Inflammation Journal Club Christina Lisk Gaudet, R.G. et al. Cytosolic Detection of the Bacterial Metabolite HBP Activates TIFA-Dependent Innate Immunity. Science 348:1251-1256, 2015.
December 7 No Seminar
14 No Seminar
Spring 2015
January 26 Outside speaker for Microbial Pathogenesis, Inflammation, and Immunology Training Program Seminar
February 9 Immunology Journal Club Cancelled – Snow
16 No Seminar
23 Microbiology Journal Club Grace Olinger Hotard, A.L. et al. 2015. Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein that Modulates Fusion Activity and Pathogenesis. J. Virol. 89:512-522
March 2 Microbiology Journal Club Matthew Gagne Gardner, M.R. et al. 2015. AAV-Expressed eCD4-Ig Provides Durable Protection from Multiple SHIV Challenges. Nature [Epub ahead of print].
9 Student Seminar Kaitlin Sawatzki
(Kepler Lab)
“An Assessment of Immunoglobulin Repertoire Sequencing: Getting Real with Big Data”
16 Immunology Journal Club Raquel Rodriguez Nice, T.J. et al. 2015. Interferon-gamma Cures Persistent Murine Norovirus Infection in the Absence of Adaptive Immunity. Science 347:269-73.
23 Postdoctoral Seminar Anna Belkina
(Snyder-Cappione Lab)
“New Insights into Immune Exhaustion Using 16-Color Flow Cytometry”
30 Microbiology Journal Club Stephanie D’Souza Selinger, C. et al. 2014. Cytokine Systems Approach Demonstrates Differences in Innate and Pro-Inflammatory host Responses Between Genetically Distinct MERS-CoV Isolates. BMC Genomics 15:1161-1176.
April 6 Student Seminars Michelle Fleury
(Dooms Lab)
and
Ludy Registre
(Sagar Lab)
“Role of Immune Cell Dysfunction in Scleroderma Pathogenesis”
and
“The Role of Anti-V3 Loop Neutralizing Antibodies on the Emergence of CXCR4 Tropism in HIV-1B”
13 Microbiology Journal Club Kaitlin Sawatzki McHeyzer-Williams, L.J. et al. 2015. Class-Switched Memory B cells Remodel BCRs within Secondary Germinal Centers. Nat. Immunol. 16:296-307.
20 No Seminar
27 Postdoctoral Seminar Tathagat Ray
(Ingalls Lab)
“Cross Talk Between Complement System and Toll-like Receptors: Implication in Inflammation and Immunity”
May 4 Immunology Journal Club Alicia Wooten Li, D. et al. 2014. IL-33 Promotes ST2-Dependent Lung Fibrosis by the Induction of Alternatively Activated Macrophages and Innate Lymphoid Cells in Mice. J. Allergy Clin. Immunol.  134:1422-1432
11 Postdoctoral Seminar Luis Agosto
(Henderson Lab)
“HIV Replication in Macrophages during P. gingivalis Co-Infection”
13 DISSERTATION DEFENSE Kristie Hilliard “The Functional Significance of the Lung-Liver Axis During Pneumonia”
27 Qualifying Exam Seminars Matthew Gagne
and
Grace Olinger
and Sila Ataca
“Interrogating the Effects of Differential Signaling on HIV Transcription using a Tunable System”
and
“Investigating the Effects of Duplications within the Attachment Glycoprotein Gene of Clinically Isolated Human Respiratory Syncytial Virus (HRSV) Strains”
and
“Characterization of Antibodies during Affinity Maturation in the Human Response to Anthrax Vaccine”
July 16 10:00 AM DISSERTATION DEFENSE Suzanne Kijewski “Mechanistic Differences in Interactions of HIV-1 and HIV-2 with Dendritic Cells”