Sections
Nephrology
Biography
Scientist with expertise in chronic lymphocytic leukemia, Toll-like receptor signaling, Parkinson’s disease and apoptosis.
Proficient in molecular/cell biology, cell culture, flow cytometry, and imaging techniques.
Experience working collaboratively, writing grants, protocols and research reports, training students and technicians.
Education
MD, Tongji Medical University
Child and Adolescent Psychology, PhD, Ludwig-Maximilians-Universität München
Medicine, BS, Tongji Medical University
Publications
Pellerin A, Tan Y, Lu S, Bonegio RG, Rifkin IR. Genetic Reduction of IRF5 Expression after Disease Initiation Reduces Disease in a Mouse Lupus Model by Impacting Systemic and End-Organ Pathogenic Pathways. J Immunol. 2023 Nov 01; 211(9):1308-1319. PMID: 37721418.
Published on 8/9/2021Pellerin A, Yasuda K, Cohen-Bucay A, Sandra V, Shukla P, Jr BKH, Nündel K, Viglianti GA, Xie Y, Klein U, Tan Y, Bonegio RG, Rifkin IR. Monoallelic IRF5 deficiency in B cells prevents murine lupus. JCI Insight. 2021 08 09; 6(15). PMID: 34197340.
Published on 1/1/2015Tan Y, Watkins AA, Freeman BB, Meyers JA, Rifkin IR, Lerner A. Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells. J Immunol. 2015 Jan 1; 194(1):101-12. PMID: 25416804.
Published on 11/6/2011Tan Y, Yu F, Pereira A, Morin P, Zhou J. Suppression of Nrdp1 toxicity by Parkin in Drosophila models. Biochem Biophys Res Commun. 2011 Dec 09; 416(1-2):18-23. PMID: 22086177.
Published on 6/1/2011Tan Y, Yamada-Mabuchi M, Arya R, St Pierre S, Tang W, Tosa M, Brachmann C, White K. Coordinated expression of cell death genes regulates neuroblast apoptosis. Development. 2011 Jun; 138(11):2197-206. PMID: 21558369.
Published on 6/15/2010Wu JN, Nguyen N, Aghazarian M, Tan Y, Sevrioukov EA, Mabuchi M, Tang W, Monserrate JP, White K, Brachmann CB. grim promotes programmed cell death of Drosophila microchaete glial cells. Mech Dev. 2010 Sep-Dec; 127(9-12):407-17. PMID: 20558283.
Published on 1/4/2005Zhong L, Tan Y, Zhou A, Yu Q, Zhou J. RING finger ubiquitin-protein isopeptide ligase Nrdp1/FLRF regulates parkin stability and activity. J Biol Chem. 2005 Mar 11; 280(10):9425-30. PMID: 15632191.
Published on 4/1/2004Tan Y, Merrow M, Roenneberg T. Photoperiodism in Neurospora crassa. J Biol Rhythms. 2004 Apr; 19(2):135-43. PMID: 15038853.
Published on 3/9/2004Tan Y, Dragovic Z, Roenneberg T, Merrow M. Entrainment dissociates transcription and translation of a circadian clock gene in neurospora. Curr Biol. 2004 Mar 09; 14(5):433-8. PMID: 15028220.
Published on 7/1/2003Merrow M, Dragovic Z, Tan Y, Meyer G, Sveric K, Mason M, Ricken J, Roenneberg T. Combining theoretical and experimental approaches to understand the circadian clock. Chronobiol Int. 2003 Jul; 20(4):559-75. PMID: 12916713.