Vijaya B. Kolachalama PhD, FAHA

Associate Professor, Computational Biomedicine

Assistant Professor, Computing & Data Sciences Administration

72 East Concord Street | (617) 358-7253
Vijaya Kolachalama
Sections

Computational Biomedicine

Centers

Whitaker Cardiovascular Institute

Evans Center for Interdisciplinary Biomedical Research

Biography

Our mission is to create methods to fit the science and not make science fit the methods.

Specifically, we are interested in the following questions that have clinical relevance:
Neurodegeneration – How can we develop software frameworks that can assist dementia screening in various settings?
Digital pathology – How can we build clinical-grade software tools to complement the pathologist workflow?

We are also interested in the following frameworks that have computational relevance:
Domain generalization – Development of deep neural networks that can generalize well across multiple data cohorts
Representation learning – Construction of efficient neural models on high resolution data to process local and contextual information

Education

BS, Indian Institute of Technology, Kharagpur, India

PhD, University of Southampton, UK

Publications

Published on 3/3/2023

Costello KE, Felson DT, Jafarzadeh SR, Guermazi A, Roemer FW, Segal NA, Lewis CE, Nevitt MC, Lewis CL, Kolachalama VB, Kumar D. Gait, physical activity and tibiofemoral cartilage damage: a longitudinal machine learning analysis in the Multicenter Osteoarthritis Study. Br J Sports Med. 2023 Mar 03. PMID: 36868795.

Published on 1/30/2023

Zhang M, Lotfollahzadeh S, Elzinad N, Yang X, Elsadawi M, Gower A, Belghasem M, Shazly T, Kolachalama VB, Chitalia V. Alleviating iatrogenic effects of paclitaxel via anti-inflammatory treatment. Res Sq. 2023 Jan 30. PMID: 36778300.

Published on 12/23/2022

Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Segal NA, Lewis CE, Nevitt MC, Kumar D. Relation of gait measures with mild unilateral knee pain during walking using machine learning. Sci Rep. 2022 Dec 23; 12(1):22200. PMID: 36564397.

Published on 10/27/2022

Zheng Y, Gindra RH, Green EJ, Burks EJ, Betke M, Beane JE, Kolachalama VB. A Graph-Transformer for Whole Slide Image Classification. IEEE Trans Med Imaging. 2022 Nov; 41(11):3003-3015. PMID: 35594209.

Published on 7/7/2022

Shazly T, Torres WM, Secemsky EA, Chitalia VC, Jaffer FA, Kolachalama VB. Understudied factors in drug-coated balloon design and evaluation: A biophysical perspective. Bioeng Transl Med. 2023 Jan; 8(1):e10370. PMID: 36684110.

Published on 7/7/2022

Amini S, Hao B, Zhang L, Song M, Gupta A, Karjadi C, Kolachalama VB, Au R, Paschalidis IC. Automated detection of mild cognitive impairment and dementia from voice recordings: A natural language processing approach. Alzheimers Dement. 2022 Jul 07. PMID: 35796399.

Published on 7/1/2022

Griffith KN, Schwartzman DA, Pizer SD, Bor J, Kolachalama VB, Jack B, Garrido MM. Local Supply Of Postdischarge Care Options Tied To Hospital Readmission Rates. Health Aff (Millwood). 2022 Jul; 41(7):1036-1044. PMID: 35787076.

Published on 6/20/2022

Qiu S, Miller MI, Joshi PS, Lee JC, Xue C, Ni Y, Wang Y, De Anda-Duran I, Hwang PH, Cramer JA, Dwyer BC, Hao H, Kaku MC, Kedar S, Lee PH, Mian AZ, Murman DL, O'Shea S, Paul AB, Saint-Hilaire MH, Alton Sartor E, Saxena AR, Shih LC, Small JE, Smith MJ, Swaminathan A, Takahashi CE, Taraschenko O, You H, Yuan J, Zhou Y, Zhu S, Alosco ML, Mez J, Stein TD, Poston KL, Au R, Kolachalama VB. Multimodal deep learning for Alzheimer's disease dementia assessment. Nat Commun. 2022 Jun 20; 13(1):3404. PMID: 35725739.

Published on 5/4/2022

Kolachalama VB. Machine learning and pre-medical education. Artif Intell Med. 2022 Jul; 129:102313. PMID: 35659392.

Published on 2/28/2022

De Anda-Duran I, Alonso CF, Libon DJ, Carmichael OT, Kolachalama VB, Suglia SF, Au R, Bazzano LA. Carotid Intima-Media Thickness and Midlife Cognitive Function: Impact of Race and Social Disparities in the Bogalusa Heart Study. Neurology. 2022 May 03; 98(18):e1828-e1836. PMID: 35228334.

View full list of 65 publications.