Vijaya B. Kolachalama PhD, FAHA

Associate Professor, Computational Biomedicine

Assistant Professor, Computing & Data Sciences Administration

72 East Concord Street | (617) 358-7253
vkola@bu.edu

Sections

Computational Biomedicine

Centers

Whitaker Cardiovascular Institute

Evans Center for Interdisciplinary Biomedical Research

Biography

We are a highly interdisciplinary research group, bringing together trainees and scientists from computer science, neuroscience, bioinformatics, physics, computing and data sciences, electrical and computer engineering, and medicine. We actively collaborate with clinicians and domain experts across diverse specialties and institutions globally. This unique convergence of disciplines has enabled us to publish across the full spectrum of scientific inquiry, from top-tier journals like Nature Medicine to premier computer science venues such as the International Conference on Machine Learning (ICML). Our mission is to create methods to fit the science and not make science fit the methods. Together, we are advancing impactful science at the intersection of AI and human health.

Websites

BU Profile

Kolachalama Laboratory

GitHub

Education

BS, Indian Institute of Technology, Kharagpur, India

PhD, University of Southampton, UK

Publications

Published on 4/23/2025

Napoleon MA, Yang X, Zhang Y, Morrissey A, Krinsky S, Lazowski A, Bouchouari H, Brahim AM, Sellinger I, Edwards T, Jose A, Lotfolhzadeh S, Almiron R, Yin W, Siracuse JJ, Francis J, Lokau J, Garbers C, Del Carmen PM, Kolachalama VB, Dries R, Nazarian RM, Nigwekar SU, Chitalia VC. Activation and targetability of TYMP-IL-6-TF signaling in the skin microenvironment in uremic calciphylaxis. Sci Transl Med. 2025 Apr 23; 17(795):eadn5772. PMID: 40267216.

PubMed

Published on 4/22/2025

Ding H, Madan S, Searls E, McNulty M, Low S, Li Z, Ho K, Rahman S, Igwe A, Popp Z, Hwang PH, De Anda-Duran I, Kolachalama VB, Mez J, Alosco ML, Thomas RJ, Au R, Lin H. Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform. Sleep Med. 2025 Jul; 131:106532. PMID: 40306226.

PubMed

Published on 4/11/2025

Gunes I, Bernstein EJ, Cowper SE, Panse G, Pradhan N, Camacho LD, Page N, Bundschuh E, Williams A, Carns M, Aren K, Fantus S, Volkmann ER, Bukiri H, Correia C, Kolachalama VB, Wilson FP, Mawe S, Mahoney JM, Hinchcliff M. Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis. Arthritis Res Ther. 2025 Apr 11; 27(1):85. PMID: 40217251.

PubMed

Published on 3/28/2025

Laudon A, Wang Z, Zou A, Sharma R, Ji J, Tan W, Kim C, Qian Y, Ye Q, Chen H, Henderson JM, Zhang C, Kolachalama VB, Lu W. Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy. Biol Methods Protoc. 2025; 10(1):bpaf024. PMID: 40223818.

PubMed

Published on 3/17/2025

Jasodanand VH, Kowshik SS, Puducheri S, Romano MF, Xu L, Au R, Kolachalama VB. AI-driven fusion of neurological work-up for assessment of biological Alzheimer's disease. medRxiv. 2025 Mar 17. PMID: 40166530.

PubMed

Published on 2/1/2025

Ahangaran M, Dawalatabad N, Karjadi C, Glass J, Au R, Kolachalama VB. Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment. Alzheimers Dement. 2025 Feb; 21(3):e70032. PMID: 40084735.

PubMed

Published on 1/30/2025

Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Elsadawi M, Kenney D, Douam F, Bosmann M, Whelan S, Cabral H, Burks EJ, Zhao G, Kolachalama V, Ravid K, Chitalia V. Tryptophan metabolism reprogramming contributes to the prothrombotic milieu in mice and humans infected with SARS-CoV-2. bioRxiv. 2025 Jan 30. PMID: 39896681.

PubMed

Published on 12/16/2024

Lauber MV, Bellitti M, Kapadia K, Jasodanand VH, Au R, Kolachalama VB. Global amyloid burden enhances network efficiency of tau propagation in the brain. J Alzheimers Dis. 2024 Dec 16; 13872877241294084. PMID: 39686595.

PubMed

Published on 11/28/2024

PubMed

Published on 11/18/2024

Ding H, Gifford K, Shih LC, Ho K, Rahman S, Igwe A, Low S, Popp Z, Searls E, Li Z, Madan S, Burk A, Hwang PH, Anda-Duran I, Kolachalama VB, Au R, Lin H. Exploring the Perspectives of Older Adults on a Digital Brain Health Platform Using Natural Language Processing: Cohort Study. JMIR Form Res. 2024 Nov 18; 8:e60453. PMID: 39556805.

PubMed

View full list of 111 publications.