Vijaya B. Kolachalama PhD, FAHA

Associate Professor, Computational Biomedicine

Assistant Professor, Computing & Data Sciences Administration

72 East Concord Street | (617) 358-7253
vkola@bu.edu

Sections

Computational Biomedicine

Centers

Whitaker Cardiovascular Institute

Evans Center for Interdisciplinary Biomedical Research

Biography

Our mission is to create methods to fit the science and not make science fit the methods.

Specifically, we are interested in the following questions that have clinical relevance:
-- Neurodegeneration: How can we develop software frameworks that can assist neurology practitioners in various real-world settings?
-- Digital pathology: How can we build clinical-grade software tools to complement the pathologist workflow?

We are also interested in the following frameworks that have computational relevance:
-- Multimodal machine learning: Efficient design of AI agents for multimodal data processing with incomplete information.
-- Representation learning: Construction of efficient neural networks on high resolution data to process local and contextual information.

Websites

BU Profile

Kolachalama Laboratory

GitHub

Education

BS, Indian Institute of Technology, Kharagpur, India

PhD, University of Southampton, UK

Publications

Published on 1/30/2025

Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Elsadawi M, Kenney D, Douam F, Bosmann M, Whelan S, Cabral H, Burks EJ, Zhao G, Kolachalama V, Ravid K, Chitalia V. Tryptophan metabolism reprogramming contributes to the prothrombotic milieu in mice and humans infected with SARS-CoV-2. bioRxiv. 2025 Jan 30. PMID: 39896681.

PubMed

Published on 12/16/2024

Lauber MV, Bellitti M, Kapadia K, Jasodanand VH, Au R, Kolachalama VB. Global amyloid burden enhances network efficiency of tau propagation in the brain. J Alzheimers Dis. 2024 Dec 16; 13872877241294084. PMID: 39686595.

PubMed

Published on 11/28/2024

Ahangaran M, Dawalatabad N, Karjadi C, Glass J, Au R, Kolachalama VB. Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment. medRxiv. 2024 Nov 28. PMID: 39649616.

PubMed

Published on 11/18/2024

Ding H, Gifford K, Shih LC, Ho K, Rahman S, Igwe A, Low S, Popp Z, Searls E, Li Z, Madan S, Burk A, Hwang PH, Anda-Duran I, Kolachalama VB, Au R, Lin H. Exploring the Perspectives of Older Adults on a Digital Brain Health Platform Using Natural Language Processing: Cohort Study. JMIR Form Res. 2024 Nov 18; 8:e60453. PMID: 39556805.

PubMed

Published on 11/2/2024

Kapadia K, Ruwali S, Malav T, Seshadri S, Seidmann A, Press DZ, Kolachalama VB. Enhancing Efficiency with an AI-Augmented Clinician in Neurology. Aging Dis. 2024 Nov 02. PMID: 39500349.

PubMed

Published on 10/25/2024

Ding H, Ho K, Searls E, Low S, Li Z, Rahman S, Madan S, Igwe A, Popp Z, Burk A, Wu H, Ding Y, Hwang PH, Anda-Duran I, Kolachalama VB, Gifford KA, Shih LC, Au R, Lin H. Assessment of Wearable Device Adherence for Monitoring Physical Activity in Older Adults: Pilot Cohort Study. JMIR Aging. 2024 Oct 25; 7:e60209. PMID: 39454101.

PubMed

Published on 10/15/2024

Gunes I, Bernstein E, Cowper SE, Panse G, Pradhan N, Camacho LD, Page N, Bundschuh E, Williams A, Carns M, Aren K, Fantus S, Volkmann ER, Bukiri H, Correia C, Wang R, Kolachalama V, Wilson FP, Mawe S, Mahoney JM, Hinchcliff M. Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis. Res Sq. 2024 Oct 15. PMID: 39483897.

PubMed

Published on 9/4/2024

Zheng Y, Conrad RD, Green EJ, Burks EJ, Betke M, Beane JE, Kolachalama VB. Graph Attention-Based Fusion of Pathology Images and Gene Expression for Prediction of Cancer Survival. IEEE Trans Med Imaging. 2024 Sep; 43(9):3085-3097. PMID: 38587959.

PubMed

Published on 7/12/2024

Jia S, Bit S, Searls E, Claus LA, Fan P, Jasodanand VH, Lauber MV, Veerapaneni D, Wang WM, Au R, Kolachalama VB. MedPodGPT: A multilingual audio-augmented large language model for medical research and education. medRxiv. 2024 Jul 12. PMID: 39040167.

PubMed

Published on 7/4/2024

Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Alvin Ang TF, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. AI-based differential diagnosis of dementia etiologies on multimodal data. Nat Med. 2024 Oct; 30(10):2977-2989. PMID: 38965435.

PubMed

View full list of 105 publications.