Vanessa Xanthakis PhD

Assistant Professor, Preventive Medicine & Epidemiology

Assistant Professor, Biostatistics

72 E. Concord Street | (617) 358-1304
Vanessa Xanthakis

Preventive Medicine & Epidemiology


Framingham Heart Study

Evans Center for Interdisciplinary Biomedical Research


Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and has a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Boston University School of Medicine and in the Biostatistics Department at Boston University School of Public Health. She is an investigator at the Framingham Heart Study and serves as the biostatistician on several investigations. She also serves as the Program Director for the Boston University T32 Program in Cardiovascular Epidemiology and the Promotion of Research In MEdical Residency (R38) program. She is the Director of Research Training for the Section of Preventive Medicine and Epidemiology. For the last 12 years, Dr. Xanthakis has focused her research on:

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.


Biostatistics, PhD, Boston University School of Public Health, 2011

Applied Mathematics, MS, University of Athens, 2001

Applied Mathematics, BS, University of Athens, 2001


Published on 10/4/2021

Vasan RS, Pan S, Larson MG, Mitchell GF, Xanthakis V. Arteriosclerosis, Atherosclerosis, and Cardiovascular Health: Joint Relations to the Incidence of Cardiovascular Disease. Hypertension. 2021 Nov; 78(5):1232-1240. PMID: 34601961.

Published on 10/4/2021

Vasan RS, Song RJ, Xanthakis V, Mitchell GF. Aortic Root Diameter and Arterial Stiffness: Conjoint Relations to the Incidence of Cardiovascular Disease in the Framingham Heart Study. Hypertension. 2021 Nov; 78(5):1278-1286. PMID: 34601969.

Published on 9/7/2021

Yola IM, Moser C, Duncan MS, Schwedhelm E, Atzler D, Maas R, Hannemann J, Böger RH, Vasan RS, Xanthakis V. Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study. PLoS One. 2021; 16(9):e0254577. PMID: 34492019.

Published on 8/13/2021

Ataklte F, Song RJ, Upadhyay A, Musa Yola I, Vasan RS, Xanthakis V. Association of Mildly Reduced Kidney Function With Cardiovascular Disease: The Framingham Heart Study. J Am Heart Assoc. 2021 Aug 17; 10(16):e020301. PMID: 34387110.

Published on 8/12/2021

Nayor M, Shah RV, Tanguay M, Blodgett JB, Chernofsky A, Miller PE, Xanthakis V, Malhotra R, Houstis NE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD. Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample. Am J Cardiol. 2021 10 15; 157:56-63. PMID: 34391575.

Published on 6/3/2021

Vasan RS, Urbina EM, Jin L, Xanthakis V. Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community. Curr Cardiol Rep. 2021 06 03; 23(7):86. PMID: 34081212.

Published on 5/14/2021

Castro-Diehl C, Ehrbar R, Obas V, Oh A, Vasan RS, Xanthakis V. Biomarkers representing key aging-related biological pathways are associated with subclinical atherosclerosis and all-cause mortality: The Framingham Study. PLoS One. 2021; 16(5):e0251308. PMID: 33989340.

Published on 5/6/2021

Xanthakis V, Sung JH, Samdarshi TE, Hill AN, Musani SK, Sims M, Gharaibeh KA, Liebson PR, Taylor HA, Vasan RS, Fox ER. Erratum. Relations Between Subclinical Disease Markers and Type 2 Diabetes, Metabolic Syndrome, and Incident Cardiovascular Disease: The Jackson Heart Study. Diabetes Care 2015;38:1082-1088. Diabetes Care. 2021 May 06. PMID: 33958426.

Published on 4/19/2021

Lin H, Castro-Diehl C, Short MI, Xanthakis V, Yola IM, Kwan AC, Mitchell GF, Larson MG, Vasan RS, Cheng S. Shared Genetic and Environmental Architecture of Cardiac Phenotypes Assessed via Echocardiography: The Framingham Heart Study. Circ Genom Precis Med. 2021 04; 14(2):e003244. PMID: 33866821.

Published on 3/31/2021

Lee J, Walker ME, Bourdillon MT, Spartano NL, Rogers GT, Jacques PF, Vasan RS, Xanthakis V. Conjoint Associations of Adherence to Physical Activity and Dietary Guidelines With Cardiometabolic Health: The Framingham Heart Study. J Am Heart Assoc. 2021 04 06; 10(7):e019800. PMID: 33784828.

View full list of 111 publications.