S. Reza Jafarzadeh DVM, MPVM, PhD
Associate Professor, Rheumatology
650 Albany St | (617) 358-9665srjafarz@bu.edu
Sections
Rheumatology
Centers
Arthritis & Autoimmune Diseases Research Center
Biography
I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.
I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.
Education
DVM, University of Tehran
MPVM, University of California, Davis
PhD, University of California, Davis
Publications
Myers LC, Bosch NA, Soltesz L, Daly KA, Campbell CI, Schwager E, Salvati E, Stevens JP, Wunsch H, Rucci JM, Jafarzadeh SR, Liu VX, Walkey AJ. Opioid Administration Practice Patterns in Patients With Acute Respiratory Failure Who Undergo Invasive Mechanical Ventilation. Crit Care Explor. 2024 Jul 01; 6(7):e1123. PMID: 39018285.
Published on 6/3/2024Myers LC, Soltesz L, Bosch N, Daly KA, Devis Y, Rucci J, Stevens J, Wunsch H, Jafarzadeh SR, Campbell CI, Liu VX, Walkey AJ. Intravenous Opioid Administration During Mechanical Ventilation and Use After Hospital Discharge. JAMA Netw Open. 2024 Jun 03; 7(6):e2417292. PMID: 38874921.
Published on 4/17/2024Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Stefanik JJ, Corrigan P, Segal NA, Lewis CE, Nevitt MC, Kumar D. Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Jul; 76(7):984-992. PMID: 38523250.
Published on 3/22/2024Bosch NA, Law AC, Shi Z, Jafarzadeh SR, Walkey AJ. A novel measure to summarize blood transfusion practice during critical illness. Transfusion. 2024 May; 64(5):784-788. PMID: 38515390.
Published on 1/1/2024Bosch NA, Myers LC, Jafarzadeh SR, Wunsch H, Stevens JP, Liu VX, Walkey AJ. Temporal Trends in Use of Opioids for Patients with Acute Respiratory Failure following "Analgesia-First" Sedation Guidelines. Ann Am Thorac Soc. 2024 Jan; 21(1):179-183. PMID: 37847821.
Published on 12/28/2023Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar; 76(3):403-408. PMID: 37750238.
Published on 10/15/2023Liew JW, Jarraya M, Guermazi A, Lynch J, Wang N, Rabasa G, Jafarzadeh SR, Nevitt M, Torner J, Lewis CE, Felson DT, Neogi T. Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study. Arthritis Rheumatol. 2023 Dec; 75(12):2161-2168. PMID: 37410792.
Published on 5/1/2023Bosch NA, Teja B, Law AC, Pang B, Jafarzadeh SR, Walkey AJ. Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock. JAMA Intern Med. 2023 May 01; 183(5):451-459. PMID: 36972033.
Published on 3/31/2023Corrigan P, Neogi T, Frey-Law L, Jafarzadeh SR, Segal N, Nevitt MC, Lewis CE, Stefanik JJ. Relation of pain sensitization to self-reported and performance-based measures of physical functioning: the Multicenter Osteoarthritis (MOST) study. Osteoarthritis Cartilage. 2023 Jul; 31(7):966-975. PMID: 37003421.
Published on 3/3/2023Costello KE, Felson DT, Jafarzadeh SR, Guermazi A, Roemer FW, Segal NA, Lewis CE, Nevitt MC, Lewis CL, Kolachalama VB, Kumar D. Gait, physical activity and tibiofemoral cartilage damage: a longitudinal machine learning analysis in the Multicenter Osteoarthritis Study. Br J Sports Med. 2023 Aug; 57(16):1018-1024. PMID: 36868795.
Media Mentions
Published on 5/19/2024
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View full list of 3 media mentions.