Noyan Gokce MD
Professor, Cardiovascular Medicine
75 E. Newton St | (617) 414-1565gokce@bu.edu
noyan.gokce@bmc.org

Sections
Cardiovascular Medicine
Centers
Whitaker Cardiovascular Institute
Boston Nutrition Obesity Research Center
Evans Center for Interdisciplinary Biomedical Research
Biography
Dr. Noyan Gokce, MD is Professor of Medicine at Chobanian and Avedisian School of Medicine and Director of Echocardiography at Boston Medical Center. He is a Fellow of the American College of Cardiology (FACC), American Society of Echocardiography (FASE), and a member of the American Society for Clinical Investigation (ASCI). He is board certified in Cardiovascular Diseases and Adult Echocardiography. He is recipient of the “Excellence in Clinical Teaching” award in 2006, 2011, 2017, and 2019 in the Cardiovascular Division. He has been awarded the “Collaborator of the Year” award in Clinical/Translational Sciences at BMC, as well as First Prize in Clinical Research at the Evans Memorial Dept. of Medicine 100th Anniversary Celebration. Dr. Gokce’s translational research focuses on elucidating mechanisms of vascular dysfunction in obesity and metabolic diseases, using both basic and clinical approaches. His laboratory has been NIH funded for 20 consecutive years and he is currently the principal investigator on several NIH R01 grants that study the relationships between dysfunctional adipose tissue in human fat stores and cardiometabolic dysfunction. These studies also seek to characterize pathogenic links between obesity, perivascular adipose remodeling, insulin resistance, inflammation, endothelial dysfunction, and angiogenesis, and investigate how medical and bariatric surgical weight loss interventions regulate adipose tissue metabolism and micro- and macro-vascular phenotypes.
Education
Medicine-Internal, MD, Tufts University School of Medicine
Biology, BA, Brandeis University
Publications
Ahmed B, Farb MG, Gokce N. Cardiometabolic implications of adipose tissue aging. Obes Rev. 2024 Nov; 25(11):e13806. PMID: 39076025.
Published on 4/25/2024Schlezinger JJ, Gokce N. Perfluoroalkyl/Polyfluoroalkyl Substances: Links to Cardiovascular Disease Risk. Circ Res. 2024 Apr 26; 134(9):1136-1159. PMID: 38662859.
Published on 10/18/2023Ahmed B, Farb MG, Karki S, D'Alessandro S, Edwards NM, Gokce N. Pericardial Adipose Tissue Thrombospondin-1 Associates With Antiangiogenesis in Ischemic Heart Disease. Am J Cardiol. 2024 Jan 01; 210:201-207. PMID: 37863116.
Published on 9/19/2023Chavkin NW, Vippa T, Jung C, McDonnell S, Hirschi KK, Gokce N, Walsh K. Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans. Front Cardiovasc Med. 2023; 10:1264479. PMID: 37795485.
Published on 1/1/2023Balakrishnan B, Gupta A, Basri R, Sharma VM, Slayton M, Gentner K, Becker CC, Karki S, Muturi H, Najjar SM, Loria AS, Gokce N, Puri V. Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction. Diabetes. 2023 Jan 01; 72(1):19-32. PMID: 36256836.
Published on 8/11/2022Gupta A, Balakrishnan B, Karki S, Slayton M, Jash S, Banerjee S, Grahn THM, Jambunathan S, Disney S, Hussein H, Kong D, Lowell BB, Natarajan P, Reddy UK, Gokce N, Sharma VM, Puri V. Human CIDEC transgene improves lipid metabolism and protects against high-fat diet-induced glucose intolerance in mice. J Biol Chem. 2022 Sep; 298(9):102347. PMID: 35963433.
Published on 7/1/2021Gokce N, Karki S, Dobyns A, Zizza E, Sroczynski E, Palmisano JN, Mazzotta C, Hamburg NM, Pernar LI, Carmine B, Carter CO, LaValley M, Hess DT, Apovian CM, Farb MG. Association of Bariatric Surgery With Vascular Outcomes. JAMA Netw Open. 2021 07 01; 4(7):e2115267. PMID: 34251443.
Published on 6/22/2021Chavkin NW, Sano S, Wang Y, Oshima K, Ogawa H, Horitani K, Sano M, MacLauchlan S, Nelson A, Setia K, Vippa T, Watanabe Y, Saucerman JJ, Hirschi KK, Gokce N, Walsh K. The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. J Am Heart Assoc. 2021 07 06; 10(13):e019904. PMID: 34155901.
Published on 1/28/2021Mazzotta C, Basu S, Gower AC, Karki S, Farb MG, Sroczynski E, Zizza E, Sarhan A, Pande AN, Walsh K, Dobrilovic N, Gokce N. Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250. PMID: 33504180.
Published on 6/7/2019Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 08 06; 140(6):487-499. PMID: 31170826.
Media Mentions
Published on 7/12/2021
Vascular Function: Another Benefit of Bariatric Surgery
View full list of 1 media mentions.