Nicole L Spartano PhD

Assistant Professor, Endocrinology, Diabetes, Nutrition & Weight Management

Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)

720 Harrison Ave | (315) 415-2040
spartano@bu.edu

Sections

Endocrinology, Diabetes, Nutrition & Weight Management

Centers

Framingham Heart Study

Evans Center for Interdisciplinary Biomedical Research

Biography

Nicole Spartano, PhD is an Assistant Professor of Medicine in Endocrinology, Diabetes, Nutrition and Weight Management at the Chobanian and Avedisian School of Medicine. She serves as the Director of the Glucose Monitoring Station at the Framingham Heart Study. This study is funded through an R01 from the National Institute of Diabetes and Digestive and Kidney Diseases (Spartano, PI) to use continuous glucose monitors in a non-diabetic population to measure glucose patterns that may predict the development of diabetes. She also serves as the Co-Director of the Physical Activity Station at the Framingham Heart Study, overseeing data collection using accelerometers (fitness trackers). She has received funding from the American Heart Association and Alzheimer's Association to understand the impact of physical activity throughout the lifecourse on brain health and the risk for dementia and Alzheimer's disease.

Dr. Spartano also has a major research interest in using mobile health technology to improve health in underserved patient populations at Boston Medical Center. She is exploring the use of continuous glucose monitors as a tool for enhancing lifestyle interventions in patients with and without diabetes mellitus. She shares a MPI role on a Focused Research Project funded by Boston University’s Hariri Institute, which facilitates collaborations of clinical and computational investigators. This team is developing a software platform that can continuously collect mobile health data from research participants and patients. The goal of creating this platform is to address challenges in privacy and in providing timely communication to medically vulnerable patients.

Dr. Spartano also teaches courses for Boston University Graduate Medical Sciences, School of Public Health, and Sargent College of Health Sciences.

Websites

BU Profile

ResearchGate

Education

PhD, Tufts University

MS, Tufts University

Biology, BS, Syracuse University

Publications

Published on 8/1/2026

Wang N, DiCorpo DA, Zhang Y, Kleinbrink E, Arnett DK, Barnard J, Blangero J, Bowden DW, Carson AP, Chen YI, Chung MK, Curran JE, Darbar D, Duggirala R, Ellinor PT, Fatkin D, Fornage M, Heard-Costa N, He J, Hou L, Kardia SLR, Kooperberg C, Loos RJF, McManus DD, Mitchell BD, Minster RL, North KE, Psaty BM, Raffield LM, Redline S, Rich SS, Roden D, Rotter JI, Shoemaker MB, Smith JD, Van Wagoner DR, Aguet F, Ardlie K, Bis JC, Brody JA, Cade BE, Clish CB, de Vries PS, Floyd JS, Freedman BI, Gabriel S, Gerzsten RE, Goodarzi MO, Gu C, Guo X, Gupta N, Heckbert SR, Hsu S, Hung YJ, Kalyani RR, Kelly TN, Kinney GL, Li C, Liu S, Liu Y, Lloyd-Jones DM, Manson JE, Mathias RA, Mercader JM, Morrison AC, Naseri T, Onengut S, Palmer ND, Peyser PA, Qi Q, Raghavan S, Reiner AP, Rooney MR, Sevilla-Gonzalez M, Sarnowski C, Smith JD, Smith JA, Spartano NL, Tahir U, Taylor KD, Tobias DK, Tracy RP, Viali S, Wang H, Wood AC, Yanek LR, Zhao W, Zheng Y, Dupuis J, Liu CT, Sladek R, Wessel J, Meigs JB, Manning AK. Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. Diabetes. 2026 Aug 01; 75(8):1477-1491. PMID: 42274313.

PubMed

Published on 11/1/2025

Haff MG, Murabito JM, Vasan RS, Spartano NL, Liu CT, Zhang X, Benjamin EJ, Lewis GD, Long MT. Physical Activity by Accelerometer Inversely Associated With Liver Fibrosis; Cross-Sectional Analysis of a Longitudinal Cohort. Liver Int. 2025 Nov; 45(11):e70380. PMID: 41055309.

PubMed

Published on 10/1/2025

Rodriguez JA, Palermo NE, Song W, Lipsitz S, Caballero AE, Samal L, Spartano NL. Lack of Association Between Hemoglobin A1c and Continuous Glucose Monitor Metrics Among Individuals with Prediabetes and Normoglycemia. Diabetes Technol Ther. 2026 Apr; 28(4):381-386. PMID: 41027845.

PubMed

Published on 9/12/2025

Ding H, Brown S, Paquette DR, Orwig TA, Spartano NL, Lin H. Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study. J Med Internet Res. 2025 Sep 12; 27:e72946. PMID: 40939123.

PubMed

Published on 7/31/2025

Bakhshi B, Sultana N, Lin H, Fei D, Vallejo V, Gatanti A, Steenkamp DW, Murabito JM, McKeown NM, Walker ME, Spartano NL. Associations of diet composition and quality with continuous glucose monitor-derived glycemic metrics in a community-based cohort. Am J Clin Nutr. 2025 Oct; 122(4):942-953. PMID: 40749968.

PubMed

Published on 6/20/2025

Rizvi N, Lin H, Beiser AS, Spartano NL. How Do Occupational Sedentary Behavior and Occupational Cognitive Complexity Relate to Cognitive Function? A Cross-Sectional Study. Health Sci Rep. 2025 Jun; 8(6):e70949. PMID: 40547068.

PubMed

Published on 6/3/2025

Wang X, Zhang Y, Pathiravasan CH, Spartano NL, Benjamin EJ, McManus DD, Lewis GD, Larson MG, Vasan RS, Murabito JM, Liu C, Nayor M. Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study. J Am Heart Assoc. 2025 Jun 03; 14(11):e039457. PMID: 40459124.

PubMed

Published on 3/17/2025

Spartano NL, Sultana N, Lin H, Cheng H, Lu S, Fei D, Murabito JM, Walker ME, Wolpert HA, Steenkamp DW. Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes. J Clin Endocrinol Metab. 2025 Mar 17; 110(4):1128-1134. PMID: 39257191.

PubMed

Published on 3/11/2025

Alexanian SM, Cheney MC, Bello Ramos JC, Spartano NL, Wolpert HA, Steenkamp DW. Impact of Meal Insulin Bolus Timing and Bedtime Snacking on Continuous Glucose Monitoring-Derived Glycemic Metrics in Hospitalized Inpatients. Diabetes Technol Ther. 2025 Jul; 27(7):511-516. PMID: 40067436.

PubMed

Published on 2/12/2025

Spartano NL, Prescott B, Walker ME, Shi E, Venkatesan G, Fei D, Lin H, Murabito JM, Ahn D, Battelino T, Edelman SV, Fleming GA, Freckmann G, Galindo RJ, Joubert M, Lansang MC, Mader JK, Mankovsky B, Mathioudakis NN, Mohan V, Peters AL, Shah VN, Spanakis EK, Waki K, Wright EE, Zilbermint M, Wolpert HA, Steenkamp DW. Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes. J Diabetes Sci Technol. 2026 May; 20(3):727-735. PMID: 39936548.

PubMed

View full list of 80 publications.