Nicholas Bosch MD, MSc
Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine
72 E. Concord Street | (617) 358-2800
Pulmonary, Allergy, Sleep & Critical Care Medicine
Dr. Bosch investigates epidemiology and outcomes in critically ill patients. Using clinical data, Dr. Bosch focuses on provider practice patterns and natural experiments to inform our understanding of the effectiveness of intensive care unit therapies. His research interests include sepsis, cardiovascular and endocrine disease during critical illness, severe alcohol withdrawal, and acute lung injury. Dr. Bosch is the principal investigator for the multicenter randomized controlled trial Awake Prone Position for Early Hypoxemia in COVID-19 (APPEX-19).
Medicine, MD, New York Medical College, 2012
MS, Boston University School of Public Health, 2020
Biological Sciences, BS, University of California, Davis, 2007
Bosch NA, Crable EL, Ackerbauer KA, Clark K, Drainoni ML, Grim V, Ieong MH, Walkey AJ, Murphy J. Implementation of a Phenobarbital-based Pathway for Severe Alcohol Withdrawal: A Mixed-Method Study. Ann Am Thorac Soc. 2021 Oct; 18(10):1708-1716. PMID: 33945771.Published on 9/1/2021
Garcia MA, Rampon GL, Doros G, Jia S, Jagan N, Gillmeyer K, Berical A, Hudspeth J, Ieong M, Modzelewski KL, Schechter-Perkins EM, Ross CS, Rucci JM, Simpson S, Walkey AJ, Bosch NA. Rationale and Design of the Awake Prone Position for Early Hypoxemia in COVID-19 Study Protocol: A Clinical Trial. Ann Am Thorac Soc. 2021 09; 18(9):1560-1566. PMID: 33647225.Published on 9/1/2021
Garcia MA, Rucci JM, Thai KK, Lu Y, Kipnis P, Go AS, Desai M, Bosch NA, Martinez A, Clancy H, Devis Y, Myers LC, Liu VX, Walkey AJ. Association between Troponin I Levels during Sepsis and Postsepsis Cardiovascular Complications. Am J Respir Crit Care Med. 2021 09 01; 204(5):557-565. PMID: 34038701.Published on 8/24/2021
Walkey AJ, Law A, Bosch NA. Lottery-Based Incentive in Ohio and COVID-19 Vaccination Rates. JAMA. 2021 08 24; 326(8):766-767. PMID: 34213530.Published on 6/24/2021
Belok SH, Bosch NA, Klings ES, Walkey AJ. Evaluation of leukopenia during sepsis as a marker of sepsis-defining organ dysfunction. PLoS One. 2021; 16(6):e0252206. PMID: 34166406.Published on 5/11/2021
Bosch NA, Teja B, Wunsch H, Walkey AJ. Practice Patterns in the Initiation of Secondary Vasopressors and Adjunctive Corticosteroids during Septic Shock in the US. Ann Am Thorac Soc. 2021 May 11. PMID: 33975530.Published on 2/5/2021
Bosch NA, Fantasia KL, Modzelewski KL, Alexanian SM, Walkey AJ. Guideline-Concordant Insulin Infusion Initiation Among Critically Ill Patients With Sepsis. Endocr Pract. 2021 Jun; 27(6):552-560. PMID: 33549815.Published on 2/1/2021
Bosch NA, Fantasia KL, Modzelewski KL, Alexanian SM, Walkey AJ. Racial Disparities in Guideline-Concordant Insulin Infusions during Critical Illness. Ann Am Thorac Soc. 2021 02; 18(2):368-371. PMID: 33001705.Published on 12/1/2020
Vail EA, Wunsch H, Pinto R, Bosch NA, Walkey AJ, Lindenauer PK, Gershengorn HB. Use of Hydrocortisone, Ascorbic Acid, and Thiamine in Adults with Septic Shock. Am J Respir Crit Care Med. 2020 12 01; 202(11):1531-1539. PMID: 32706593.Published on 12/1/2020
Wunsch H, Hill AD, Bosch N, Adhikari NKJ, Rubenfeld G, Walkey A, Ferreyro BL, Tillmann BW, Amaral ACKB, Scales DC, Fan E, Cuthbertson BH, Fowler RA. Comparison of 2 Triage Scoring Guidelines for Allocation of Mechanical Ventilators. JAMA Netw Open. 2020 12 01; 3(12):e2029250. PMID: 33315112.
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