Michael F. Holick MD, PhD

Professor, Endocrinology, Diabetes, Nutrition & Weight Management

Professor, Pharmacology, Physiology & Biophysics

85 E. Newton St | (617) 638-4546
mfholick@bu.edu

Sections

Endocrinology, Diabetes, Nutrition & Weight Management

Centers

Evans Center for Interdisciplinary Biomedical Research

Biography

Dr. Holick has made numerous contributions to the field of the biochemistry, physiology, metabolism, and photobiology of vitamin D for human nutrition. Dr. Holick has established global recommendations advising sunlight exposure as an integral source of vitamin D. He has helped increase awareness in the pediatric and medical communities regarding vitamin D deficiency pandemic, and its role in causing not only metabolic bone disease, and osteoporosis in adults, but increasing risk of children and adults developing preeclampsia, common deadly cancers, schizophrenia, infectious diseases including TB and influenza, autoimmune diseases including type 1 diabetes and multiple sclerosis, type 2 diabetes, stroke and heart disease.

Dr. Holick is a Diplomate of the American Board of Internal Medicine, a Fellow of the American College of Nutrition, and a member of the American Association of Physicians. He is the recipient of numerous awards and honors, including the General Clinical Research Centers Program Award for Excellence in Clinical Research from NIH, American College of Nutrition’s Communication Media Award, Best Docs in America, the Linus Pauling Functional Medicine Award from the Institute for Functional Medicine and the Linus Pauling Prize for Human Nutrition. Dr. Holick serves on a number of national committees and editorial boards and has organized and/or co-chaired several international symposia. He served as the chair for the Endocrine Society’s Practice Guidelines on Vitamin D. He has authored more than 400 peer-reviewed publications, and written more than 200 review articles, as well as numerous book chapters. He has acted as editor and/or co-editor on 13 books, and has written The UV Advantage in 2004 and The Vitamin D Solution in 2010 and helped develop the dminder.info app.

Other Positions

Websites

BU Profile

Vitamin D, Skin, and Bone Research Laboratory

The Vitamin D Solution

Boston Medical Center Provider Profile

ResearchGate

Education

MD, University of Wisconsin Madison

PhD, University of Wisconsin Madison

MS, University of Wisconsin Madison

BS, Seton Hall University

Publications

Published on 2/20/2026

Slominski AT, Tuckey RC, Slominski RM, Holick MF, Jetten AM. On the role of cholesterol, vitamin D, lumisterol, and tachysterol signaling in psoriasis. J Invest Dermatol. 2026 Apr; 146(4):887-889. PMID: 41718524.

PubMed

Published on 12/31/2025

Slominski AT, Slominski RM, Kamal M, Holick MF, Tuckey RC, Reiter RJ, Li W, Jetten AM. Is Vitamin D Signaling Regulated by and Does It Regulate Circadian Rhythms? FASEB J. 2025 Dec 31; 39(24):e71321. PMID: 41396154.

PubMed

Published on 12/19/2025

Shah R, Das L, Bansal D, Sachdeva N, Holick MF, Dutta P, Medenica S, Marwaha RK. An open-label interventional study on efficacy and safety of 25 µg of daily calcifediol capsule versus 100 µg of cholecalciferol sachets in apparently healthy volunteers. J Nutr Sci. 2026; 15:e1. PMID: 41541626.

PubMed

Published on 9/20/2025

Uçar N, Shirvani A, Holick MF. Peripheral Thermoregulatory Modulation for Hot Flash Management: Efficacy of Novel Wrist Cooling Device in Cancer Treatment-Induced and Menopausal Vasomotor Symptoms. AACE Endocrinol Diabetes. 2025; 12(4):276-285. PMID: 41467131.

PubMed

Published on 8/1/2025

Shirvani A, Holick MF. Effectiveness of SOLIUS UVB Light System in Enhancing Serum 25-Hydroxyvitamin D Concentrations: A Randomized Controlled Trial. Anticancer Res. 2025 Aug; 45(8):3327-3339. PMID: 40750396.

PubMed

Published on 7/7/2025

Pludowski P, Wójcik M, Jaworski M, Ochocinska A, Grant WB, Holick MF. Least Significant Change (LSC) for Serum Concentrations of 25-Hydroxyvitamin D. Nutrients. 2025 Jul 07; 17(13). PMID: 40647349.

PubMed

Published on 6/25/2025

Uçar N, Pickering RT, Mueller PM, Deeney JT, Morales Suárez-Varela M, Soriano JM, Holick MF. Vitamin D3, 25-Hydroxyvitamin D3, and 1,25-Dihydroxyvitamin D3 Uptake in Cultured Human Mature Adipocytes. Nutrients. 2025 Jun 25; 17(13). PMID: 40647210.

PubMed

Published on 5/21/2025

Alansari K, Davidson BL, Holick MF. A randomized comparison of intramuscular high-dose versus oral maintenance vitamin D to prevent severe exacerbations in deficient/insufficient asthmatic children. J Allergy Clin Immunol Glob. 2025 Aug; 4(3):100497. PMID: 40529482.

PubMed

Published on 2/22/2025

Nikooyeh B, Holick MF, Abdollahi Z, Rasekhi H, Amini M, Ghodsi D, Yari Z, Rabiei S, Kalayi A, Zahedirad M, Yazdani H, Rismanchi M, Neyestani TR. Effectiveness and Potential Toxicity of Bread Fortification With Vitamin D in General Population: A Predictive Modeling Study. J Nutr. 2025 Apr; 155(4):1268-1277. PMID: 39993476.

PubMed

Published on 2/19/2025

Shirvani P, Shirvani A, Holick MF. Mitochondrial Dysfunction and Its Potential Molecular Interplay in Hypermobile Ehlers-Danlos Syndrome: A Scoping Review Bridging Cellular Energetics and Genetic Pathways. Curr Issues Mol Biol. 2025 Feb 19; 47(2). PMID: 39996855.

PubMed

View full list of 661 publications.