Matthew G. Nayor MD, MPH

Associate Professor, Cardiovascular Medicine

Assistant Professor, Preventive Medicine & Epidemiology

75 E. Newton St | (617) 638-8771
mnayor@bu.edu

Sections

Cardiovascular Medicine

Preventive Medicine & Epidemiology

Biography

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Websites

BU Profile

Twitter

ResearchGate

ORCID ID: 0000-0002-6993-9396

Education

MD, New York University School of Medicine

MPH, Harvard School of Public Health

History, BA, University of Michigan at Ann Arbor

Publications

Published on 4/23/2026

Qian F, Gajjar P, Prescott B, Mitchell GF, Xanthakis V, Rade JJ, Nayor M. Modifiable Correlates With Systemic Thromboxane Generation and Association With Cardiovascular Outcomes: Results From the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324561. PMID: 42021731.

PubMed

Published on 4/7/2026

Landsteiner I, Stolze LK, Peterson TE, Perry A, Lin P, Sheng Q, Zhao S, Amancherla K, Mi MY, Ikoma T, Cohen LP, Giverts I, Campain J, Lima JAC, Post WS, Taylor KD, Gerszten R, Rich SS, Tracy R, Durda P, Wood AC, Malhotra R, Rotter JI, Clish C, Nayor M, Gamazon ER, Shah RV, Lewis GD. Multi-Organ Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure with Preserved Ejection Fraction. Circulation. 2026 Apr 07; 153(18):1362-84. PMID: 41944041.

PubMed

Published on 4/2/2026

El-Sabawi B, Huang X, Lin P, Anwar MY, Betti M, Kim N, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze LK, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Proteogenomic Analysis of Coronary Artery Calcification in Human Populations. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324171. PMID: 41924874.

PubMed

Published on 3/2/2026

Qian F, Davis DN, Nayor M. Healthy Lifestyle After Hypertension-A Call to Action. JAMA Netw Open. 2026 Mar 02; 9(3):e260927. PMID: 41842902.

PubMed

Published on 2/17/2026

Perry AS, O'Connor C, Pavicic M, Sheng Q, Farber-Eger E, Sarkar A, Lin P, Evans P, Tanriverdi K, Risitano A, Peters AE, Chen H, Upadhya B, Whellan DJ, Pastva A, Mentz RJ, Bertoni A, Semelka C, Brubaker PH, Molina AJA, Newland R, Nelson B, Lane M, Sullivan KA, Townsend A, Vlot A, Nsoh B, Allen PD, Wells Q, Reeves GR, Jacobson D, Kitzman DW, Gamazon ER, Nayor M, Shah RV. A multi-layered approach to elucidate mechanisms of physical function in response to rehabilitation in heart failure with preserved ejection fraction. medRxiv. 2026 Feb 17. PMID: 41757200.

PubMed

Published on 2/12/2026

Davis DN, Gajjar P, Xanthakis V, Lloyd-Jones D, Nayor M. Refined Heart Failure Stages Incorporating Cardiorespiratory Fitness Are Differentially Associated With Heart Failure Risk in the Community. J Am Heart Assoc. 2026 Feb 17; 15(4):e045791. PMID: 41676947.

PubMed

Published on 12/2/2025

Yee T, Gajjar P, Gopal DM, Nayor M. Obesity burden among heart failure patients in an urban safety net hospital: Implications for GLP-1 agonist therapy. Am Heart J Plus. 2026 Jan; 61:100688. PMID: 41439268.

PubMed

Published on 11/12/2025

Robbins JM, Benson M, Verkerke ARP, Tiwari G, Deng S, Rao P, Tahir UA, Avila-Pacheco J, Shi X, Guan Y, Tendoh FG, Barber JL, Miller PE, Perry AS, Hall ME, Wood AC, Taylor KD, Post WS, Rich SS, Nayor M, Wilson JG, Lewis GD, Shah RV, Rotter JI, Summers SA, Raffield LM, Kajimura S, Bouchard C, Clish CB, Sarzynski MA, Gerszten RE. N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness. Circulation. 2026 Jan 06; 153(1):47-58. PMID: 41221589.

PubMed

Published on 10/31/2025

Landman JM, Highland HM, Perry AS, Howard AG, Sheng Q, Lorenz A, Palmer AB, Zhao S, Zhu W, Zhang X, Buchanan VL, Frankel EG, Roshani R, Scartozzi A, Farber-Eger EH, Anwar MY, Sprinkles JK, Breidenbach A, Wang TC, Ballard CA, Nayor M, Tamaroff J, Gutierrez A, Petty LE, Petty AS, Lippi B, Fernandez-Rhodes L, Chen HH, Krishnan M, Graff M, Meyer KA, Lee M, Young KL, Wells Q, Freedman JE, Gamazon ER, McCormick JB, Fisher-Hoch SP, Gordon-Larsen P, Below JE, North KE, Shah RV. Proteomic signatures of pediatric cardiovascular and cardiometabolic traits demonstrate long-term modifiable drivers of adult disease. medRxiv. 2025 Oct 31. PMID: 41282792.

PubMed

Published on 8/23/2025

Jha M, Dong Z, Ruda MM, Prescott B, Xanthakis V, Nayor M, Gajjar P, Larson MG, Benjamin EJ, Vasan RS, Mitchell GF, Tsao CW. Associations of cardiovascular health with arterial health in adults free of cardiovascular disease. Am J Prev Cardiol. 2025 Sep; 23:101083. PMID: 40918934.

PubMed

View full list of 108 publications.