Matthew G. Nayor MD, MPH

Associate Professor, Cardiovascular Medicine

Associate Professor, Preventive Medicine & Epidemiology

75 E. Newton St | (617) 638-8771
Matthew Nayor
Sections

Cardiovascular Medicine

Preventive Medicine & Epidemiology

Biography

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Education

MD, New York University School of Medicine

MPH, Harvard School of Public Health

History, BA, University of Michigan at Ann Arbor

Publications

Published on 11/1/2026

Bakhshi B, Lin H, Sultana N, Healey E, Queen H, Gao G, Claudel SE, Minetti ET, Mitchell GF, Murabito JM, Lloyd-Jones DM, Cheney MC, Steenkamp DW, Nayor M, Xanthakis V, Walker ME, Spartano NL. Beyond Traditional Glycemic Measures: CGM Glycemic Profiles Reveal Associations With Cardiometabolic Risk in Individuals Without Diabetes. Diabetes Care. 2026 Nov 01; 49(11):2040-2049. PMID: 42752803.

Published on 10/8/2026

Qian F, Nayor M, Shah RV. Metabolic Insights Into Dynamic Glucose Trajectories: Importance of Perturbation. Circ Res. 2026 Oct 09; 139(9):e329600. PMID: 42848865.

Published on 9/28/2026

Bakhshi B, Sultana N, Nayor M, Lin H, Ma J, Steenkamp DW, Long MT, Spartano NL, Walker ME. Dynamic Measures of Glycemia in Relation to Hepatic Features in Adults Without Diabetes. medRxiv. 2026 Sep 28. PMID: 42856390.

Published on 9/11/2026

Landman JM, Highland HM, Perry AS, Howard AG, Sheng Q, Lorenz A, Palmer AB, Zhao S, Zhu W, Zhang X, Buchanan VL, Frankel EG, Roshani R, Scartozzi A, Farber-Eger EH, Anwar MY, Sprinkles JK, Breidenbach A, Wang TC, Ballard CA, Nayor M, Tamaroff J, Gutierrez A, Petty LE, Petty AS, Lippi B, Fernandez-Rhodes L, Chen HH, Krishnan M, Graff M, Meyer KA, Lee M, Young KL, Wells Q, Tanriverdi K, Freedman JE, Gamazon ER, McCormick JB, Fisher-Hoch SP, Gordon-Larsen P, Below JE, North KE, Shah RV. Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes. Nat Metab. 2026 Sep; 8(9):2007-2022. PMID: 42728365.

Published on 8/18/2026

Krishnan V, Ravichandran S, Gajjar P, Perry AS, Miller PE, Vasan RS, Shah RV, Lewis GD, Kiel DP, Nayor M. Body Composition, Obesity, and Cardiorespiratory Fitness in the Community. Med Sci Sports Exerc. 2026 Aug 18. PMID: 42611635.

Published on 8/3/2026

Davis DN, Aghi A, Gajjar P, Miller P, Holder EX, Nayor M, Palmer JR. Psychosocial Stressors and Heart Failure Risk Among Black Women in the US. JAMA Netw Open. 2026 Aug 03; 9(8):e2629320. PMID: 42611516.

Published on 6/6/2026

Barnard ME, Xu NN, Holder EX, Jones D, Nayor M, Ko NY, Palmer JR. Hypertension, use of antihypertensive medications and breast cancer survival among Black women. Breast Cancer Res. 2026 Jun 06; 28(1). PMID: 42251447.

Published on 4/23/2026

Qian F, Gajjar P, Prescott B, Mitchell GF, Xanthakis V, Rade JJ, Nayor M. Modifiable Correlates With Systemic Thromboxane Generation and Association With Cardiovascular Outcomes: Results From the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324561. PMID: 42021731.

Published on 4/7/2026

Landsteiner I, Stolze LK, Peterson TE, Perry A, Lin P, Sheng Q, Zhao S, Amancherla K, Mi MY, Ikoma T, Cohen LP, Giverts I, Campain J, Lima JAC, Post WS, Taylor KD, Gerszten R, Rich SS, Tracy R, Durda P, Wood AC, Malhotra R, Rotter JI, Clish C, Nayor M, Gamazon ER, Shah RV, Lewis GD. Multi-Organ Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure with Preserved Ejection Fraction. Circulation. 2026 Apr 07; 153(18):1362-84. PMID: 41944041.

Published on 4/2/2026

El-Sabawi B, Huang X, Lin P, Anwar MY, Betti M, Kim N, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze LK, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Proteogenomic Analysis of Coronary Artery Calcification in Human Populations. Arterioscler Thromb Vasc Biol. 2026 Jun; 46(6):e324171. PMID: 41924874.

View full list of 115 publications.