Matthew G. Nayor MD, MPH
Associate Professor, Cardiovascular Medicine
Assistant Professor, Preventive Medicine & Epidemiology
75 E. Newton St | (617) 638-8771mnayor@bu.edu
Sections
Cardiovascular Medicine
Preventive Medicine & Epidemiology
Biography
Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.
Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.
Education
MD, New York University School of Medicine
MPH, Harvard School of Public Health
History, BA, University of Michigan at Ann Arbor
Publications
Jha M, Dong Z, Ruda MM, Prescott B, Xanthakis V, Nayor M, Gajjar P, Larson MG, Benjamin EJ, Vasan RS, Mitchell GF, Tsao CW. Associations of cardiovascular health with arterial health in adults free of cardiovascular disease. Am J Prev Cardiol. 2025 Sep; 23:101083. PMID: 40918934.
Published on 7/26/2025Lindman BR, Perry AS, Lance ML, Amancherla K, Kim N, Sheng Q, Lin P, Pfeiffer RD, Farber-Eger E, Fearon WF, Kapadia S, Kumbhani DJ, Gillam L, Mallugari RR, Gupta DK, Miller FJ, Vatterott A, Jackson N, Su YR, Tomasek K, Absi T, Freedman JE, Nayor M, Das S, Wells QS, Dweck MR, Gerszten RE, Gamazon ER, Tucker NR, Shah R, Elmariah S. Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure. Nat Commun. 2025 Jul 26; 16(1):6889. PMID: 40715126.
Published on 7/3/2025Mi MY, Perry AS, Krishnan V, Nayor M. Epidemiology and Cardiovascular Benefits of Physical Activity and Exercise. Circ Res. 2025 Jul 07; 137(2):120-138. PMID: 40608856.
Published on 6/3/2025Wang X, Zhang Y, Pathiravasan CH, Spartano NL, Benjamin EJ, McManus DD, Lewis GD, Larson MG, Vasan RS, Murabito JM, Liu C, Nayor M. Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study. J Am Heart Assoc. 2025 Jun 03; 14(11):e039457. PMID: 40459124.
Published on 5/31/2025Toro C, Daniels AS, Prescott B, Xanthakis V, Nayor M, Gajjar P, Benjamin EJ, Preis SR. Association of life's essential 8 score with incidence of atrial fibrillation: The Framingham heart study. Am J Prev Cardiol. 2025 Sep; 23:101018. PMID: 40585337.
Published on 5/15/2025El-Sabawi B, Tanriverdi K, Gajjar P, Nayor M, Landman JM, Below JE, Haff M, Long M, Ezpeleta M, Freedman JE, Varady K, Shah R, Perry AS. Circulating Proteomics Identifies a Dynamic Profile of Hepatic Steatosis During Metabolic Intervention. J Am Heart Assoc. 2025 May 20; 14(10):e037100. PMID: 40371575.
Published on 3/7/2025El-Sabawi B, Betti M, Lin P, Huang X, Kim N, Yaser Anwar M, Perry AS, Perera BLA, Gajjar P, Colangelo LA, Amancherla K, Sheng Q, Zhao S, Stolze L, Farber-Eger E, Landman JM, Miller PE, Liu GY, Das S, Wells QS, Terry JG, Lloyd-Jones D, Das S, Khan SS, North KE, Below J, Nayor M, Kalhan R, Carr JJ, Gamazon ER, Shah RV. Molecular architecture of human atherosclerosis revealed through integrative human genetics. medRxiv. 2025 Mar 07. PMID: 40093223.
Published on 2/14/2025Iyer KR, Clarke SL, Guarischi-Sousa R, Gjoni K, Heath AS, Young EP, Stitziel NO, Laurie C, Broome JG, Khan AT, Lewis JP, Xu H, Montasser ME, Ashley KE, Hasbani NR, Boerwinkle E, Morrison AC, Chami N, Do R, Rocheleau G, Lloyd-Jones DM, Lemaitre RN, Bis JC, Floyd JS, Kinney GL, Bowden DW, Palmer ND, Benjamin EJ, Nayor M, Yanek LR, Kral BG, Becker LC, Kardia SLR, Smith JA, Bielak LF, Norwood AF, Min YI, Carson AP, Post WS, Rich SS, Herrington D, Guo X, Taylor KD, Manson JE, Franceschini N, Pollard KS, Mitchell BD, Loos RJF, Fornage M, Hou L, Psaty BM, Young KA, Regan EA, Freedman BI, Vasan RS, Levy D, Mathias RA, Peyser PA, Raffield LM, Kooperberg C, Reiner AP, Rotter JI, Jun G, de Vries PS, Assimes TL. Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants. J Am Heart Assoc. 2025 Feb 18; 14(4):e036499. PMID: 39950338.
Published on 1/7/2025Rade JJ, Kronsberg SS, Kickler TS, Vasan RS, Xanthakis V, Nayor MG, Barton BA. Association of Systemic Thromboxane Generation With Risk of Developing Heart Failure. J Am Coll Cardiol. 2025 Jan 07; 85(1):58-70. PMID: 39779056.
Published on 1/1/2025Florea VV, Gajjar P, Huang S, Tang J, Zhao S, Davenport M, Mi MY, Haff M, Zhang X, Miller PE, Vasan RS, Liu CT, Lewis GD, Shah RV, Long MT, Nayor M. Hepatic Steatosis and Fibrosis, Cardiorespiratory Fitness, and Metabolic Mediators in the Community. Liver Int. 2025 Jan; 45(1):e16147. PMID: 39673712.
Media Mentions
Published on 12/3/2022
How I’m Staying in Shape by Turning My Daily Stroll Into Hard Exercise
Published on 3/9/2022
Exercise Intervention May Slow HF Progression Before Disease Takes Hold
Published on 11/2/2021
How to improve your fitness if you sit down all day, according to experts
Published on 10/18/2021
Published on 9/30/2021
Why researchers say you should pick up the pace during exercise
Published on 9/29/2021
The exercise routine that's 3 times more beneficial than walking, according to researchers
Published on 9/28/2021
This Workout Is Three Times Better For Your Health Than Walking, New Study Says
Published on 9/27/2021
Bouts of moderate to vigorous exercise can drastically improve a person's fitness
Published on 9/26/2021
Moderate, vigorous exercise one of the best exercises for getting fit and staying healthy
Published on 9/24/2021
Intense workouts boost fitness 3x more than 10,000 steps a day
View full list of 14 media mentions.