Markus Bosmann MD

Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine

Professor, Pathology & Laboratory Medicine

72 E. Concord Street | (617) 358-1225
mbosmann@bu.edu

Sections

Pulmonary, Allergy, Sleep & Critical Care Medicine

Centers

Pulmonary Center

Evans Center for Interdisciplinary Biomedical Research

Biography

Markus Bosmann is an immunologist whose research focuses on elucidating the mechanisms underlying infection-associated inflammation and tissue injury in pneumonia, acute lung injury and sepsis. Dr. Bosmann leads a multidisciplinary research team that collaborates with academic and industry partners and employs advanced molecular biology and immunology approaches, including transgenic in vivo models, human biospecimens, and transcriptomic and proteomic analyses supported by advanced bioinformatics.

Other Positions

Websites

BU Profile

Pulmonary, Allergy, Sleep, and Critical Care Medicine Faculty

UROP

Education

Medicine, MD, Goethe University Frankfurt

Publications

Published on 6/15/2026

Vasilew K, Jayaraman A, Platten J, Xu S, Josinsky S, Roewe J, Mimmler M, Kilroy J, Echahidi F, Kaya Z, Zamboni DS, Reinhardt C, Bosmann M. Polyphosphates Attenuate Interleukin-12 Production in Macrophages Infected With Legionella pneumophila. FASEB J. 2026 Jun 15; 40(11):e71954. PMID: 42219888.

PubMed

Published on 4/6/2026

Garo LP, Brueck K, Walachowski S, Jayaraman A, Strueve M, Xu S, Yang H, Helmkamp M, Choi SH, Reinhardt C, Bosmann M. Proton-activated chloride channel 1 is essential for innate host defense against bacterial sepsis. Proc Natl Acad Sci U S A. 2026 Apr 14; 123(15):e2515768123. PMID: 41941636.

PubMed

Published on 1/28/2026

Garo LP, Brueck K, Walachowski S, Jayaraman A, Strueve M, Xu S, Yang H, Helmkamp M, Choi SH, Reinhardt C, Bosmann M. Proton-Activated Chloride Channel 1 (PACC1) is essential for innate host defense against bacterial sepsis. bioRxiv. 2026 Jan 28. PMID: 41509271.

PubMed

Published on 1/5/2026

Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Francis C, Elsadawi M, Wu Wong DJ, Kenney D, Douam F, Bosmann M, Whelan SA, Cabral H, Burks EJ, Zhao G, Kolachalama VB, Ravid K, Chitalia VC. Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2. Blood Vessel Thromb Hemost. 2026 Feb; 3(1):100128. PMID: 41743170.

PubMed

Published on 2/25/2025

Soucy AM, Brune JE, Jayaraman A, Shenoy AT, Korkmaz FT, Etesami NS, Hiller BE, Martin IM, Goltry WN, Ha CT, Crossland NA, Campbell JD, Beach TG, Traber KE, Jones MR, Quinton LJ, Bosmann M, Frevert CW, Mizgerd JP. Transcriptomic responses of lung mesenchymal cells during pneumonia. JCI Insight. 2025 Feb 25; 10(7). PMID: 39998887.

PubMed

Published on 2/4/2025

Subramaniam S, Jose A, Kenney D, O'Connell AK, Bosmann M, Douam F, Crossland N. Challenging the notion of endothelial infection by SARS-CoV-2: insights from the current scientific evidence. Front Immunol. 2025; 16:1443932. PMID: 39967675.

PubMed

Published on 1/30/2025

Subramaniam S, Napoleon MA, Lotfollahzadeh S, Kamal MH, Kurniawan H, Elsadawi M, Kenney D, Douam F, Bosmann M, Whelan S, Cabral H, Burks EJ, Zhao G, Kolachalama V, Ravid K, Chitalia V. Tryptophan metabolism reprogramming contributes to the prothrombotic milieu in mice and humans infected with SARS-CoV-2. bioRxiv. 2025 Jan 30. PMID: 39896681.

PubMed

Published on 11/19/2024

Walachowski S, Garo L, Sharma A, Jayaraman A, Noon J, Reinhardt C, Bosmann M. Disruption of the C5a/C5aR1 axis confers protection against hookworm infection in lung. Front Immunol. 2024; 15:1475165. PMID: 39628481.

PubMed

Published on 10/18/2024

Riehl DR, Sharma A, Roewe J, Reinhardt C, Schäfer K, Bosmann M. Reply to Chong et al.: Investigating TGFß1 biological activities using genetically engineered mouse strains. Proc Natl Acad Sci U S A. 2024 Oct 29; 121(44):e2408647121. PMID: 39423253.

PubMed

Published on 8/27/2024

Jayaraman A, Walachowski S, Bosmann M. The complement system: A key player in the host response to infections. Eur J Immunol. 2024 Nov; 54(11):e2350814. PMID: 39188171.

PubMed

View full list of 89 publications.