Lee J. Quinton PhD
Center Faculty Member, Pulmonary Center
Adjunct Associate Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine
72 E. Concord Street | (617) 358-1087lquinton@bu.edu
Sections
Pulmonary, Allergy, Sleep & Critical Care Medicine
Centers
Pulmonary Center
Evans Center for Interdisciplinary Biomedical Research
Biography
My expertise lies in the areas of the biology of acute pulmonary inflammation and the innate immune response to microorganisms in the lung.
Other Positions
Websites
Pulmonary, Allergy, Sleep & Critical Care Medicine Faculty
Education
Physiology, PhD, Louisiana State University
Microbiology, BS, University of Southern Mississippi
Publications
Korkmaz FT, Quinton LJ. Extra-pulmonary control of respiratory defense. Cell Immunol. 2024; 401-402:104841. PMID: 38878619.
Published on 4/23/2024Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells. Front Immunol. 2024; 15:1382638. PMID: 38715601.
Published on 4/15/2024Gao KM, Chiang K, Jiang Z, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration. Cell Rep. 2024 Apr 23; 43(4):114114. PMID: 38625791.
Published on 9/14/2023Lyon De Ana C, Shenoy AT, Barker KA, Arafa EI, Etesami NS, Korkmaz FT, Soucy AM, Breen MP, Martin IMC, Tilton BR, Devarajan P, Crossland NA, Pihl RMF, Goltry WN, Belkina AC, Jones MR, Quinton LJ, Mizgerd JP. GL7 ligand expression defines a novel subset of CD4+ TRM cells in lungs recovered from pneumococcus. Mucosal Immunol. 2023 Oct; 16(5):699-710. PMID: 37604254.
Published on 7/27/2023Gao KM, Chiang K, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs. bioRxiv. 2023 Jul 27. PMID: 37547024.
Published on 12/8/2022Korkmaz FT, Shenoy AT, Symer EM, Baird LA, Odom CV, Arafa EI, Dimbo EL, Na E, Molina-Arocho W, Brudner M, Standiford TJ, Mehta JL, Sawamura T, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury. JCI Insight. 2022 Dec 08; 7(23). PMID: 36264633.
Published on 3/30/2022Sharma A, Noon JB, Kontodimas K, Garo LP, Platten J, Quinton LJ, Urban JF, Reinhardt C, Bosmann M. IL-27 Enhances ?d T Cell-Mediated Innate Resistance to Primary Hookworm Infection in the Lungs. J Immunol. 2022 Apr 15; 208(8):2008-2018. PMID: 35354611.
Published on 3/8/2022Arafa EI, Shenoy AT, Barker KA, Etesami NS, Martin IM, Lyon De Ana C, Na E, Odom CV, Goltry WN, Korkmaz FT, Wooten AK, Belkina AC, Guillon A, Forsberg EC, Jones MR, Quinton LJ, Mizgerd JP. Recruitment and training of alveolar macrophages after pneumococcal pneumonia. JCI Insight. 2022 Mar 08; 7(5). PMID: 35133985.
Published on 2/9/2022Na E, Allen E, Baird LA, Odom CV, Korkmaz FT, Shenoy AT, Matschulat AM, Jones MR, Kotton DN, Mizgerd JP, Varelas X, Traber KE, Quinton LJ. Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 01; 322(4):L550-L563. PMID: 35137631.
Published on 2/7/2022Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 03 17; 90(3):e0049121. PMID: 35130455.