Katrina E. Traber MD, PhD

Assistant Professor, Pulmonary, Allergy, Sleep & Critical Care Medicine

72 E. Concord Street | (617) 638-5214
Katrina Traber
Sections

Pulmonary, Allergy, Sleep & Critical Care Medicine

Centers

Pulmonary Center

Evans Center for Interdisciplinary Biomedical Research

Biography

The long-term goal of the Traber Lab is to identify and develop new strategies to treat severe neutrophil-based sequelae of pneumonia such as ARDS and sepsis. To achieve this goal, we use in vivo and in vitro models of pneumonia to investigate mechanisms of neutrophil dysfunction in acute lung infections. Currently, we have been using two broad approaches to understand neutrophil biology. First, we are examining modulation of the neutrophil transcriptome during neutrophil migration from circulation to the alveolar space. Second, we are investigating how Oncostatin M (OSM), an IL-6 family cytokine produced by neutrophils in many acute and chronic inflammatory settings, including pneumonia, ARDS and sepsis potentiates neutrophil migration to the alveoli during pneumonia.

If you are interested in joining our research group, please contact Dr. Traber at katraber@bu.edu.

Education

Medicine-Internal, MD, New York University School of Medicine, 2007

Medical Sciences & Management, PhD, New York University School of Medicine, 2005

Medical Sciences & Management, MS, New York University School of Medicine, 2003

Cell & Molecular Biology, BA, Wesleyan University, 1997

Publications

Published on 9/1/2021

Traber KE, Center DM. Toward a More Precise Solution to Asthma Therapy. Am J Respir Cell Mol Biol. 2021 09; 65(3):241-242. PMID: 34153196.

Published on 9/1/2021

Odom CV, Kim Y, Burgess CL, Baird LA, Korkmaz FT, Na E, Shenoy AT, Arafa EI, Lam TT, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Liver-Dependent Lung Remodeling during Systemic Inflammation Shapes Responses to Secondary Infection. J Immunol. 2021 Oct 01; 207(7):1891-1902. PMID: 34470857.

Published on 3/17/2021

Traber KE, Dimbo EL, Shenoy AT, Symer EM, Allen E, Mizgerd JP, Quinton LJ. Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia. Infect Immun. 2021 03 17; 89(4). PMID: 33526570.

Published on 2/27/2020

Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Pneumonia recovery reprograms the alveolar macrophage pool. JCI Insight. 2020 02 27; 5(4). PMID: 31990682.

Published on 8/15/2019

Traber KE, Dimbo EL, Symer EM, Korkmaz FT, Jones MR, Mizgerd JP, Quinton LJ. Roles of interleukin-11 during acute bacterial pneumonia. PLoS One. 2019; 14(8):e0221029. PMID: 31415618.

Published on 7/23/2019

Kim Y, Allen E, Baird LA, Symer EM, Korkmaz FT, Na E, Odom CV, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. NF-?B RelA Is Required for Hepatoprotection during Pneumonia and Sepsis. Infect Immun. 2019 08; 87(8). PMID: 31160364.

Published on 9/28/2017

Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017 Oct 05; 21(4):472-488.e10. PMID: 28965766.

Published on 5/18/2017

Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, Mizgerd JP, Quinton LJ. Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L548-L558. PMID: 28522567.

Published on 10/1/2015

Traber KE, Hilliard KL, Allen E, Wasserman GA, Yamamoto K, Jones MR, Mizgerd JP, Quinton LJ. Induction of STAT3-Dependent CXCL5 Expression and Neutrophil Recruitment by Oncostatin-M during Pneumonia. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):479-88. PMID: 25692402.

Published on 9/1/2015

Hilliard KL, Allen E, Traber KE, Yamamoto K, Stauffer NM, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ. The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):378-90. PMID: 25607543.

View full list of 14 publications.